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Corresponding author: Blaine A. Mathison ( blaine.mathison@aruplab.com ) Academic editor: Matthew Wayland
© 2021 Blaine A. Mathison, Sarah G. H. Sapp.
This is an open access article distributed under the terms of the CC0 Public Domain Dedication.
Citation:
Mathison BA, Sapp SGH (2021) An annotated checklist of the eukaryotic parasites of humans, exclusive of fungi and algae. ZooKeys 1069: 1-313. https://doi.org/10.3897/zookeys.1069.67403
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The classification of “parasites” in the medical field is a challenging notion, a group which historically has included all eukaryotes exclusive of fungi that invade and derive resources from the human host. Since antiquity, humans have been identifying and documenting parasitic infections, and this collective catalog of parasitic agents has expanded considerably with technology. As our understanding of species boundaries and the use of molecular tools has evolved, so has our concept of the taxonomy of human parasites. Consequently, new species have been recognized while others have been relegated to synonyms. On the other hand, the decline of expertise in classical parasitology and limited curricula have led to a loss of awareness of many rarely encountered species. Here, we provide a comprehensive checklist of all reported eukaryotic organisms (excluding fungi and allied taxa) parasitizing humans resulting in 274 genus-group taxa and 848 species-group taxa. For each species, or genus where indicated, a concise summary of geographic distribution, natural hosts, route of transmission and site within human host, and vectored pathogens are presented. Ubiquitous, human-adapted species as well as very rare, incidental zoonotic organisms are discussed in this annotated checklist. We also provide a list of 79 excluded genera and species that have been previously reported as human parasites but are not believed to be true human parasites or represent misidentifications or taxonomic changes.
Acanthocephalans, arthropods, cestodes, leeches, nematodes, parasitology, protozoa, trematodes
The online Oxford English dictionary defines a parasite as: ‘an organism that lives in or on an organism of another species (its host) and benefits by deriving nutrients at the other’s expense’ (LEXICO 2020). From a strictly biological perspective, this definition can cover a wide variety of organisms, including, but not limited to, bacteria, viruses, fungi, helminths (worms), protozoans, cnidarians, tardigrades, rotifers, mollusks, and arthropods. However, in the historical concept of the medical community, the term ‘parasite’ refers to animals and other eukaryotic organisms with animal-like affinities, and is usually limited to the protozoans, helminths, and arthropods.
Historically, human parasites have been classified within the broad Linnaean kingdom of ‘Animals’ and divided into taxa with formal categorical names (phylum, class, order, family, etc.). While traditional Linnaean taxa are still commonly used for helminths and arthropods, it is becoming more common to use clade-based systems devoid of formal designations, especially with the taxa collectively called protozoans. Much of this work comes from a better understanding of the evolutionary relationships of organisms based on both morphological and molecular analyses (
Currently, eukaryotes are classified into two domains, Amorphea and Diaphoretickes, as well as additional large clades that do not fit into either of those domains. Within domains are large clades commonly referred to as supergroups. Eukaryotic parasitic organisms fall into five supergroups within these domains: SAR, Archaeplastida, Excavates, Amoebozoa, and Opisthokonta (
The Amoebozoa include many of the human parasites historically referred to as amebae, including the intestinal amebae Entamoeba, Endolimax, and Iodamoeba, and several of the ‘free-living’ amebae such as Balamuthia and Acanthamoeba (
The SAR (which commonly refers to Stramenopiles-Alveolates-Rhizaria) includes parasitic coccidians (e.g., Toxoplasma, Cyclospora, Cystoisospora), gregarines (Cryptosporidium), piroplasmids (Babesia), haemosporidians (Plasmodium), ciliophores (Balantioides, formerly Balantidium), and the stremenopile Blastocystis (
Within the SAR, the coccidians, gregarines, piroplasmids, and hemosporidians are obligate parasites and part of the clade Apicomplexa that are characterized by a structure called an apical complex that is used for penetration of the host cell. Motility is usually by gliding or body flexion and feeding is by pinocystosis (ingestion by budding of small vesicles from the cell membrane). Apicomplexans may have one or two hosts and reproduce by sexual reproduction, the end result of which is an oocyst that when mature contains sporozoites that are the infectious stage for a new host (
The only human parasitic ‘ciliate’ is Balantioides (formerly Balantidium, syn. Neobalantidium). Movement is by numerous cilia and feeding is by phagocytosis. It forms an environmentally-hardy cyst that is the infectious stage for a new host (
Blastocystis is an enigmatic organism that has historically been variably classified among coccidians, fungi, and algae. The life cycle is still not completely understood, but it has been proposed that it reproduces by binary fission of vacuolar forms within the host and infects a new host via environmentally hardy cysts. Both vacuolar forms and cysts can be detected in stool specimens, and the variability in morphology of the former has created numerous descriptive terms. It has also been suggested it has a third form, an amoeboid form, that is responsible for pathogenesis in the host, but this hypothesis is not yet broadly accepted (
The Excavates includes the traditional ‘flagellates’, such as Giardia, Trypanosoma, Dientamoeba, Chilomastix, Leishmania, and Trichomonas, as well as amoeboflagellates, such as Naegleria (
The Opisthokonta includes the arthropods, leeches, and helminths, all within the clade Metazoa (
The cestodes are obligate parasites that usually reside in the small intestine of their definitive host. Most have multiple-host life cycles, and the definitive host becomes infected after ingestion of a larval stage encysted in the tissues of an intermediate host. Adults are long, ribbon-like organisms that have three main body regions: scolex (for attachment to the intestinal mucosa of the definitive host), neck (the base of the strobila), and the strobila (the main body, which is made of up individual segments called proglottids). Historically, cestodes that parasitize humans were divided into two categories: Pseudophyllidea (Dibothriocephalus, Adenocephalus, Diphyllobothrium), and Cyclophyllidea (Taenia, Dipylidium, Hymenolepis, several others). However, Pseudophyllidea has been abandoned in favor of two broad groups, Bothriocephalidea and Diphyllobothriidea, the latter of which contains human parasites (
The trematodes that infect humans are all within Digenea and are also obligate parasites with multi-host life cycles. All parasitic species of humans have a snail as a first intermediate host, and many digeneans have second intermediate hosts or paratenic hosts that may comprise a variety of animals; in some species, infective stages are encysted in the environment, including on the surface of plants. Adults are usually hermaphroditic, apart from the schistosomes which are dioecious but live in copula. Adults have two muscular suckers, an oral sucker for attachment and feeding and a ventral sucker (acetabulum) for attachment. Infection of the human host is either by direct penetration of the cercaria larval stage (Schistosoma) or ingestion of the metacercaria larval stage in an intermediate animal host or on contaminated plants (
The acanthocephalans are zoonotic parasites in humans. While superficially similar to nematodes, they are more closely related to the rotifers, or possibly nested within Rotifera, proper (
The nematodes are a large and diverse group of organisms, most of which are free-living, although some major parasitic lineages are of great public health importance. Despite their diversity in nature, few species parasitize humans with any regularity. Two major clades of human parasites are Dorylaimia and Chromadoria, which vary greatly in their biology, route of transmission, and morphology. Most nematodes have six developmental stages: egg, four larval stages (L1-L4), and adult (L5); some larviparous species do not lay eggs. For most parasitic nematodes of humans, the infectious stage is the L3 larva, this fact is often called the ‘Rule of the Infective Third State’. Notable exceptions are members of the Trichinellida, for which the infectious stage is the L1 larva, and Eustrongylides for which the infectious stage is believed to be the precocious L4 (
The arthropods are the largest group of Metazoa, but relatively few species are adapted to parasitism on humans. Two main clades are the Chelicerata and Mandibulata, which can be broadly separated by the structure of their mouthparts. The Chelicerata includes the mites and ticks. The Mandibulata includes Pancrustacea, which contains the clades Crustacea (crustaceans) and Hexapoda (insects). The only parasitic crustaceans of humans are zoonotic pentastomids (tongueworms). The pancrustacean clade Hexapoda includes parasitic insects such as lice, fleas, beg bugs, triatomine (kissing) bugs, and myiasis-causing flies. Arthropods are characterized by a jointed exoskeleton containing chitin. Development is variable and can be gradual (hemimetabolous) or complete (holometabolous). Holometabolous insects have morphologically and biologically markedly different life cycles stages including larvae, pupae, and adults (
Here we provide an updated checklist of the parasitic protozoans, helminths, annelids, and arthropods of humans, nearly 20 years since the last such endeavor (
The bulk of this manuscript is an annotated checklist of protozoan, helminthic, annelid, and arthropod parasites reported from the human host, based on extensive literature searches through April 2021. A systematic literature search of the PubMed database (U.S. National Library of Medicine National Institutes of Health; https://www.ncbi.nlm.nih.gov/pubmed), Google Scholar (https://scholar.google.com/) and Google (https://www.google.com) was also performed using the keyword search phrases using various taxa in combination with human infection and case reports. We aimed to include all protozoan and helminthic parasites known to be reported from humans. The leeches and arthropods, however, provided a special challenge, as an exhaustive list of every sanguinivorous species that may feed on a human host would be large and beyond the scope of the audience. For the arthropods, the focus is on ectoparasites that spend prolonged time on the human host (lice, sarcoptid and demodecid mites, hard ticks, myiasis-causing flies, Tunga fleas) and visceral parasites (pentastomids). For leeches and arthropods that are short-term blood feeders or biters, such as non-Tunga fleas, soft ticks, zoonotic biting mites, bed bugs, and triatomine bugs, the focus is on those species that are commonly associated with humans and/or vector medically-important pathogens. Sanguinivorous flies (mosquitoes, black flies, deer flies, etc.) are not included, nor are those flies and other insects (e.g., cockroaches) that may passively transmit pathogens. Arthropods that are considered medically important due to envenomation, stings, or urticarial and allergic reactions are also not included.
Suprageneric taxa are listed in a hierarchal system lacking formal designations, following Adl et al. (
For organisms traditionally classified as protozoans (Amoebozoa, Excavates, and SAR), clades above the traditional ‘family’ level follow Adl and colleagues (
Species, and genera for which isolates from human cases have not been characterized at the species level, have at least four bullet-points of information: 1) Geographic distribution, 2) Natural hosts, 3) Route of infection, and 4) Site in/on human host. In addition, many of the arthropods and leeches also have an additional bullet-point, 5) Vectored pathogens.
Geographic distribution. This is the known geographic distribution of a given species or genus. For widespread organisms, the distribution is presented generally (e.g., Worldwide, North America, Circumtropical). For organisms that are more geographically restricted, the information is presented at the country level.
Natural hosts. These are the hosts that are part of the parasite’s natural life cycle. For multi-host parasites, the hosts are presented in developmental order, starting with the first intermediate host and finishing with the definitive host. Hosts for species or genera with broad host ranges are presented generally (e.g., mammals, carnivores, birds), while hosts for parasites that are more host specific are presented at a more granular level (e.g., mosquitoes in the genus Anopheles).
Route of infection. This is route through which the human host becomes infected or colonized.
Site in/on human host. This is where the parasite resides in the human host, and includes both the typical site as well as common sites of ectopic infection.
Vectored pathogens. This bullet-point is for all the arthropods, except for the pentastomids and most of the myiasis-causing fly larvae, and leeches. It provides information on infectious agents (bacteria, viruses, parasites) that are pathogenic for the human host that are transmitted by the given arthropod. It includes agents that are believed to be vectored by a given arthropod in a natural setting and does not include agents that have simply been detected in an arthropod using molecular surveillance or in experimental models.
For all taxonomic levels, select synonyms are presented, especially for names that show up frequently in the literature regarding human cases.
Lastly, a list of excluded species is presented. These are species that have been reported as human parasites but are either not believed to be true parasites in the human host, represent data based on misidentifications, or are invalid names. The excluded species are presented alphabetically.
Genus Vermamoeba Smirnov et al., 2011
Vermamoeba vermiformis (Page, 1967)
Geographic distribution. Worldwide (
Natural host. None; occurs in natural freshwater environments, surface water, soil, and biofilms. Humans are incidental hosts (
Route of infection. Presumably environmental exposure into eyes, mucus membranes, and wounds (
Site in human host. Skin and soft tissues, eye (
Notes. Previous records of Harmannella from human clinical specimens probably refer to this species.
●●● Euamoebida Lepşi, 1960 sensu Smirnov et al., 2011
●●●● Hartmannellidae Volkonsky, 1931
Genus Hartmannella Alexeiff, 1912
Geographic distribution. Worldwide.
Natural host. None (environmental); humans are incidental hosts (
Route of infection. Unknown; presumed environmental exposure and contamination (
Site in human host. Intestinal tract (
Notes. Most extraintestinal reports of human infection with Hartmanella apply to H. vermiformis Page, which is now in the genus Vermamoeba.
●●● Entamoebida Cavalier-Smith, 1993
●●●● Entamoebidae Chatton, 1925
Genus Endolimax Kuenen & Swellengrebel, 1913
Endolimax nana (Wenyon et O’Connor, 1917)
Geographic distribution. Worldwide (
Natural host. Humans (
Route of infection. Ingestion of mature cysts in fecally contaminated water, food, fomites(
Site in human host. Large intestine, cecum, colon (
Genus Entamoeba Casagrandi & Barbagallo, 1895
Entamoeba bangladeshi Royer et al., 2012
Geographic distribution. Southeast Asia, sub-Saharan Africa (
Natural host. Humans (
Route of infection. Ingestion of mature cysts in fecally contaminated water, food, fomites (
Site in human host. Large intestine, cecum, colon (
Entamoeba coli (Grassi, 1879)
Entamoeba hominis Casagrandi & Barbagallo, 1897
Entamoeba loeschi Lesage, 1908
Councilmania lafleuri Kofoid & Swezy, 1921
Geographic distribution. Worldwide (
Natural hosts. Humans, monkeys (
Route of infection. Ingestion of mature cysts in fecally contaminated water, food, fomites (
Site in human host. Large intestine, cecum, colon (
Entamoeba chattoni Swellengrebel, 1914
Geographic distribution. Africa (
Natural hosts. Non-human primates. Zoonotic in humans (
Route of infection. Ingestion of mature cysts in fecally contaminated water, food, fomites (
Site in human host. Large intestine, cecum, colon (
Entamoeba dispar Brumpt, 1925
Geographic distribution. Worldwide (
Natural hosts. Humans, chimpanzee, baboons, macaques (
Route of infection. Ingestion of mature cysts in fecally contaminated water, food, fomites (
Site in human host. Large intestine, cecum, colon (
Entamoeba gingivali s (Gros, 1849)
Amoeba buccalis Steinberg, 1862
Amoeba dentalis Grassi, 1879
Amoeba kartulis Doflein, 1901
Entamoeba maxillaris Kartulis, 1906
Entamoeba canibuccalis Smith, 1938
Endamoeba confusa Craig, 1916
Entamoeba equibuccalis Simitch, 1938
Entamoeba suigingivalis Tumka, 1959
Geographic distribution. Worldwide (
Natural hosts. Humans, horses, pigs, cats, monkeys (
Route of infection. Person-to-person contact (
Site in human host. Oral cavity; ectopic colonization of urogenital tract (
Entamoeba hartmanni Von Prowazek, 1912
Entamoeba histolytica, small race
Entamoeba minuta Woodcock & Penfold, 1916
Entamoeba tenuis Kuenen & Swellengrebel, 1917
Entamoeba minutissima Brug, 1917
Geographic distribution. Worldwide (
Natural host. Humans (
Route of infection. Ingestion of mature cysts in fecally contaminated water, food, fomites (
Site in human host. Large intestine, cecum, colon (
Entamoeba histolytica Schaudinn, 1903
Amoeba coli Lösch, 1875
Amoeba dysenteriae Councilman & Lafleur, 1891
Entamoeba africana Hartmann & Von Prowazek, 1907
Entamoeba schaudinii Lesage, 1908
Entamoeba minuta Elmassian, 1909
Entamoeba nipponica Koidzumi, 1909
Entamoeba brasiliensis Aragao, 1912
Entamoeba venaticum Darling, 1915
Entamoeba caudata Carini & Reichenow, 1949
Geographic distribution. Worldwide; endemic areas of clinical amebiasis include Central and South America, Africa, Southeast Asia (
Natural host. Humans (
Route of infection. Ingestion of mature cysts in fecally contaminated water, food, fomites; oral-anal sex (
Site in human host. Large intestine, cecum, colon; ectopic colonization of liver, skin, lungs, brain (
Entamoeba moshkovskii (Tshalaia, 1941)
Entamoeba histolytica, Laredo strain
Entamoeba histolytica, Huff strain
Geographic distribution. Presumed worldwide; high areas of endemicity include Australia, India, Bangladesh, Tanzania, Pakistan, Iran (
Natural host. Humans (
Route of infection. Ingestion of mature cysts in fecally contaminated water, food, fomites (
Site in human host. Large intestine, cecum, colon (
Entamoeba nuttalli (Castellani, 1908)
Loeschia duboscqi Mathis, 1913
Amoeba ateles Eichhorn & Gallagher, 1916
Loeschia cynomolgi Brug, 1923
Geographic distribution. Native to Southeast Asia, probably worldwide in zoos and from the animal trade (
Natural hosts. Non-human primates. Zoonotic in humans (
Route of infection. Ingestion of mature cysts in fecally contaminated water, food, fomites.
Site in human host. Large intestine, cecum, colon (
Entamoeba polecki (Von Prowazek, 1912)
Entamoeba debliecki Nieschulz, 1923
Geographic distribution. Worldwide; spots of high endemicity include Venezuela, Iran, Southeast Asia, Papua New Guinea (
Natural hosts. Pigs, monkeys. Zoonotic in humans (
Route of infection. Ingestion of mature cysts in fecally contaminated water, food, fomites (
Site in human host. Large intestine, cecum, colon (
Genus Iodamoeba Dobell, 1919
Iodamoeba buetschlii (Von Prowazek, 1912)
Geographic distribution. Worldwide (
Natural host. Human (
Route of infection. Ingestion of mature cysts in fecally contaminated water, food, fomites (
Site in human host. Large intestine, cecum, colon (
●●● Thecamoebida Schaeffer, 1926, emend. Smirnov et al., 2011
●●●● Thecamoebidae Schaeffer, 1926, emend. Smirnov et al., 2011
Genus Sappinia Dangeard, 1896
Sappinia pedata Dangeard, 1896
Geographic distribution. Presumed worldwide (
Natural host. None (environmental); humans are incidental hosts
Route of infection. Presumably by the entry of cysts or trophozoites through mucous membranes (e.g., nasal passages) or broken skin (
Site in human host. Central nervous system (CNS) (
●●● Acanthopodida Page, 1976
●●●● Acanthamoebidae Sawyer & Griffin, 1975
Genus Acanthamoeba Volonsky, 1931
Notes. Clinically, Acanthamoeba species are usually characterized by their genotypes rather than traditional Linnaean binominal nomenclature (
Acanthamoeba Genotype T1
Geographic distribution. Presumed worldwide (
Natural host. None (environmental); humans are incidental hosts.
Route of infection. Entry of environmental trophozoites or cysts through mucous membranes (e.g., eye, nasal passages) or broken skin (
Site in human host. CNS (
Acanthamoeba Genotype T2
Geographic distribution. Presumed worldwide (
Natural host. None (environmental); humans are incidental hosts.
Route of infection. Entry of environmental trophozoites or cysts through mucous membranes (e.g., eye, nasal passages) (
Site in human host. Eye (
Acanthamoeba Genotype T3
Geographic distribution. Presumed worldwide (
Natural host. None (environmental); humans are incidental hosts.
Route of infection. Entry of environmental trophozoites or cysts through mucous membranes (e.g., eye, nasal passages) (
Site in human host. Eye (
Acanthamoeba Genotype T4
Geographic distribution. Worldwide (
Natural host. None (environmental); humans are incidental hosts.
Route of infection. Entry of environmental trophozoites or cysts through mucous membranes (e.g., eye, nasal passages) or broken skin (
Site in human host. Eye, skin, lung, brain, sinus cavity, disseminated infection (
Acanthamoeba Genotype T5
Geographic distribution. Presumed worldwide (
Natural host. None (environmental); humans are incidental hosts.
Route of infection. Entry of environmental trophozoites or cysts through mucous membranes (e.g., eye, nasal passages) (
Site in human host. Eye (
Acanthamoeba Genotype T6
Geographic distribution. Presumed worldwide (
Natural host. None (environmental); humans are incidental hosts.
Route of infection. Entry of environmental trophozoites or cysts through mucous membranes (e.g., eye, nasal passages) (
Site in human host. Eye (
Acanthamoeba Genotype T8
Geographic distribution. Presumed worldwide (
Natural host. None (environmental); humans are incidental hosts
Route of infection. Entry of environmental trophozoites or cysts through mucous membranes (e.g., eye, nasal passages) (
Site in human host. Eye (
Acanthamoeba Genotype T10
Geographic distribution. Presumed worldwide (
Natural host. None (environmental); humans are incidental hosts
Route of infection. Entry of environmental trophozoites or cysts through mucous membranes (e.g., eye, nasal passages) or broken skin (
Site in human host. CNS, eye (
Acanthamoeba Genotype T11
Geographic distribution. Presumed worldwide (
Natural host. None (environmental); humans are incidental hosts.
Route of infection. Entry of environmental trophozoites or cysts through mucous membranes (e.g., eye, nasal passages) (
Site in human host. Eye (
Acanthamoeba Genotype T12
Geographic distribution. Presumed worldwide (
Natural host. None (environmental); humans are incidental hosts.
Route of infection. Entry of environmental trophozoites or cysts through mucous membranes (e.g., eye, nasal passages) or broken skin (
Site in human host. CNS (
Acanthamoeba Genotype T13
Geographic distribution. Presumed worldwide (
Natural host. None (environmental); humans are incidental hosts.
Route of infection. Entry of environmental trophozoites or cysts through mucous membranes (e.g., eye, nasal passages) (
Site in human host. Eye (
Acanthamoeba Genotype T15
Geographic distribution. Presumed worldwide (
Natural host. None (environmental); humans are incidental hosts.
Route of infection. Entry of environmental trophozoites or cysts through mucous membranes (e.g., eye, nasal passages) (
Site in human host. Eye (
●●●● Balamuthiidae Cavalier-Smith et al., 2004
Genus Balamuthia Visvesvara et al., 1993
Balamuthia mandrillaris Visvesvara et al., 1993
Geographic distribution. Worldwide (
Natural host. None (environmental); humans are incidental hosts.
Route of infection. Entry of environmental trophozoites or cysts through mucous membranes (e.g., eye, nasal passages) or broken skin (
Site in human host. Disseminated infection with predilection for CNS (
●●● Opalozoa Cavalier-Smith, 1991, emend. Cavalier-Smith et al., 2006
●●●● Opalinata Wenyon, 1926, emend. Cavalier-Smith, 1997
Genus Blastocystis Alexeieff, 1911
Notes. As the molecular epidemiology is becoming better understood, it is becoming less common to recognize Blastocystis by traditional Linnaean binominal nomenclature but rather by their genetic subtypes (
Blastocystis subtype 1
Geographic distribution. Worldwide (
Natural hosts. Various mammals. Zoonotic in humans (
Route of infection. Ingestion of cyst-forms and/or vacuolar-forms in contaminated food, water, fomites (
Site in human host. Large intestine (
Blastocystis subtype 2
Geographic distribution. Worldwide (
Natural hosts. Non-human primates, pigs. Zoonotic in humans (
Route of infection. Ingestion of cyst-forms and/or vacuolar-forms in contaminated food, water, fomites (
Site in human host. Large intestine (
Blastocystis subtype 3
Geographic distribution. Worldwide (
Natural hosts. Humans (
Route of infection. Ingestion of cyst-forms and/or vacuolar-forms in contaminated food, water, fomites (
Site in human host. Large intestine (
Blastocystis subtype 4
Geographic distribution. Worldwide (
Natural hosts. Rodents. Zoonotic in humans (
Route of infection. Ingestion of cyst-forms and/or vacuolar-forms in contaminated food, water, fomites (
Site in human host. Large intestine (
Blastocystis subtype 5
Geographic distribution. Worldwide (
Natural hosts. Pigs, cattle. Zoonotic in humans (
Route of infection. Ingestion of cyst-forms and/or vacuolar-forms in contaminated food, water, fomites (
Site in human host. Large intestine (
Blastocystis subtype 6
Geographic distribution. Worldwide (
Natural hosts. Birds. Zoonotic in humans (
Route of infection. Ingestion of cyst-forms and/or vacuolar-forms in contaminated food, water, fomites (
Site in human host. Large intestine (
Blastocystis subtype 7
Geographic distribution. Worldwide (
Natural hosts. Birds. Zoonotic in humans (
Route of infection. Ingestion of cyst-forms and/or vacuolar-forms in contaminated food, water, fomites (
Site in human host. Large intestine (
Blastocystis subtype 8
Geographic distribution. Worldwide (
Natural hosts. Monkeys, birds. Zoonotic in humans (
Route of infection. Ingestion of cyst-forms and/or vacuolar-forms in contaminated food, water, fomites (
Site in human host. Large intestine (
Blastocystis subtype 9
Geographic distribution. Worldwide (
Natural hosts. Unknown; presumed zoonotic in humans (
Route of infection. Ingestion of cyst-forms and/or vacuolar-forms in contaminated food, water, fomites (
Site in human host. Large intestine (
Blastocystis subtype 12
Geographic distribution. Worldwide (
Natural hosts. Goats, cattle. Zoonotic in humans (
Route of infection. Ingestion of cyst-forms and/or vacuolar-forms in contaminated food, water, fomites (
Site in human host. Large intestine (
●●● Colpodellidae Simpson & Patterson, 1996
Genus Colpodella Cienkowski, 1865
Geographic distribution. Worldwide (
Natural hosts. None; free-living predators of other protozoans. Humans are incidental hosts (
Route of infection. Unknown, proposed transmission via the bite of ticks in the genus Ixodes (
Site in human host. Blood (
Notes. In nature, Colpodella species are free-living predators of other protozoans. Copodella-like organisms have been diagnosed twice in patients from China, one from blood (
●●● Aconoidasida Mehlhorn et al., 1980
Hematazoa Vivier, 1982
●●●● Haemospororida Danilewsky, 1885
●●●●● Plasmodiidae Mesnil, 1903
Genus Plasmodium Marchiafava & Celli, 1885
Plasmodium brasilianum Gonder et von Berenberg-Gossler, 1908
Geographic distribution. Brazil, Venezuela, Colombia , Panama, Peru (
Natural hosts. Intermediate hosts are New World monkeys. Arthropod vector and definitive hosts are mosquitoes in the genus Anopheles. Zoonotic in humans as an intermediate host (
Route of infection. Introduction of sporozoites via the bite of infected Anopheles mosquito (
Site in human host. Liver (initial infection), blood (
Notes. It has been suggested that P. brasilianum is conspecific with P. malariae and that P. malariae adapted to non-human primates in Latin America after being introduced from Africa (
Plasmodium coatneyi Eyles et al., 1962
Geographic distribution. Peninsular Malaysia, Philippines (
Natural hosts. Intermediate host is the crab-eating macaque (Macaca fascicularis). Arthropod vector and definitive hosts are mosquitoes in the genus Anopheles. Zoonotic in humans as an intermediate host (
Route of infection. Introduction of sporozoites via the bite of infected Anopheles mosquito (
Site in human host. Liver (initial infection), blood (
Plasmodium cynomolgi Mayer, 1907
Geographic distribution. Southeast Asia (
Natural hosts. Intermediate hosts are macaques. Arthropod vector and definitive hosts are mosquitoes in the genus Anopheles. Zoonotic in humans as an intermediate host (
Route of infection. Introduction of sporozoites via the bite of infected Anopheles mosquito (
Site in human host. Liver (initial infection, chronic sequestration), blood (
Plasmodium falciparum (Welch, 1897)
Oscillaria malariae Laveran, 1881
Haemamoeba praecox Feletti & Grassi, 1890
Haemamoeba immaculata Grassi, 1891
Haemamoeba laverani Labbe, 1894
Haemosporidium sedecimanae Lewkowicz, 1897
Haemosporidium vigesimotertianae Lewkowicz, 1897
Geographic distribution. Circumtropical; sub-Saharan Africa, Asia, Latin America, Caribbean (
Natural hosts. Intermediate hosts are humans. Arthropod vector and definitive hosts are mosquitoes in the genus Anopheles (
Route of infection. Introduction of sporozoites via the bite of infected Anopheles mosquito (
Site in human host. Liver (initial infection), blood, CNS (cerebral malaria) (
Plasmodium inui Helberstaedter & Von Prowazek, 1907
Geographic distribution. Southeast Asia (
Natural hosts. Intermediate hosts are Old World monkeys. Arthropod vector and definitive hosts are mosquitoes in the genus Anopheles. Zoonotic in humans as an intermediate host (
Route of infection. Introduction of sporozoites via the bite of infected Anopheles mosquito (
Site in human host. Liver (initial infection), blood (
Plasmodium knowlesi Sinton & Mulligan, 1932
Geographic distribution. Southeast Asia (
Natural hosts. Intermediate hosts are macaques. Arthropod vector and definitive hosts are mosquitoes in the genus Anopheles. Zoonotic in humans as an intermediate host (
Route of infection. Introduction of sporozoites via the bite of infected Anopheles mosquito (
Site in human host. Liver (initial infection), blood (
Plasmodium malariae (Grassi & Feletti, 1890)
Plasmodium quartanae Celli & Sanfelice, 1891
Haematosporidium tertianae Labbe, 1894
Geographic distribution. Sub-Saharan Africa, Southeast Asia, Indonesia, Pacific Islands, Amazonian South America (
Natural hosts. Intermediate hosts are humans; non-human primates in Latin America are reservoir hosts. Arthropod vector and definitive hosts are mosquitoes in the genus Anopheles (
Route of infection. Introduction of sporozoites via the bite of infected Anopheles mosquito (
Site in human host. Liver (initial infection), blood (
Plasmodium ovale curtisi Sutherland et al., 2010
Geographic distribution. Western sub-Saharan Africa, Southeast Asia (
Natural hosts. Intermediate hosts are humans. Arthropod vector and definitive hosts are mosquitoes in the genus Anopheles (
Route of infection. Introduction of sporozoites via the bite of infected Anopheles mosquito (
Site in human host. Liver (initial infection, chronic sequestration), blood (
Notes. With the separation of P. ovale into the subspecies P. ovale curtisi and P. o. wallikeri, the epidemiology of the two species in not well understood. Both subspecies are sympatric at the country level in several African countries, but their individual distributions in Southeast Asia are not well defined (
Plasmodium ovale wallikeri Sutherland et al., 2010
Geographic distribution. Western sub-Saharan Africa, Southeast Asia (
Natural hosts. Intermediate hosts are humans. Arthropod vector and definitive hosts are mosquitoes in the genus Anopheles (
Route of infection. Introduction of sporozoites via the bite of infected Anopheles mosquito (
Site in human host. Liver (initial infection, chronic sequestration), blood (
Notes. With the separation of P. ovale into the subspecies P. ovale curtisi and P. o. wallikeri, the epidemiology of the two species in not well understood. Both subspecies are sympatric at the country level in several African countries, but their individual distributions in Southeast Asia are not well defined (
Plasmodium schwetzi Brumpt, 1938
Geographic distribution. Tropical Africa (
Natural hosts. Intermediate hosts are gorillas and chimpanzees. Arthropod vector and definitive hosts are mosquitoes in the genus Anopheles. Zoonotic in humans as intermediate hosts (
Route of infection. Introduction of sporozoites via the bite of infected Anopheles mosquito (
Site in human host. Liver (initial infection, presumed chronic sequestration), blood (
Plasmodium simiovale Dissanaike, Nelson & Garnham, 1965
Geographic distribution. Sri Lanka, Malaysia (
Natural hosts. Intermediate hosts is the toque macaque (Macaca sinica). Arthropod vector and definitive hosts are mosquitoes in the genus Anopheles. Zoonotic in humans as intermediate hosts (
Route of infection. Introduction of sporozoites via the bite of infected Anopheles mosquito (
Site in human host. Liver (initial infection, chronic sequestration), blood (
Plasmodium simium Fonseca, 1951
Geographic distribution. Brazil (
Natural hosts. Intermediate hosts are howler monkeys and capuchins. Arthropod vector and definitive hosts are mosquitoes in the genus Anopheles. Zoonotic in humans as intermediate hosts (
Route of infection. Introduction of sporozoites via the bite of infected Anopheles mosquito (
Site in human host. Liver (initial infection, chronic sequestration), blood (
Notes. It has been suggested P. simium is conspecific with P. vivax, and that P. vivax adapted to non-human primates in Latin America after being introduced by humans (
Plasmodium vivax (Grassi & Feletii, 1890)
Haemamoeba malariae Feletti & Grassi, 1890, in part
Haemosporidium tertianae Lewkowicz, 1897
Plasmodium camarense Ziemann, 1915
Geographic distribution. Africa (east, Horn of Africa, and Madagascar), Central and South America, Central Asia, Indian Subcontinent, Southeast Asia, Korean Peninsula (
Natural hosts. Intermediate hosts are humans; non-human primates can serve as reservoir hosts. Arthropod vector and definitive hosts are mosquitoes in the genus Anopheles (
Route of infection. Introduction of sporozoites via the bite of infected Anopheles mosquito (
Site in human host. Liver (initial infection, chronic sequestration), blood, CNS (
●●●● Piroplasmorida Wenyon, 1926
●●●●● Babesiidae Poche, 1913
Genus Babesia Starcovivi, 1893
Babesia divergens M’Fadyean & Stockman, 1911
Geographic distribution. Europe (
Natural hosts. Intermediate hosts are primarily cattle. Arthropod vector and definitive hosts are ticks in the genus Ixodes, primarily I. ricinus. Zoonotic in humans as intermediate hosts (
Route of infection. Introduction of sporozoites via the bite of the Ixodes tick vector; person-to-person transmission via blood and solid organ transplants (
Site in human host. Blood (
Babesia duncani
Babesia strain WA1
Babesia strain WA2
Babesia strain CA5
Babesia strain CA6
Geographic distribution. Western and northern North America (
Natural hosts. Intermediate hosts are suspected as being mule deer (Odocoileus hemionus). Arthropod vector and definitive host is believed to be the tick Dermacentor albipictus. Zoonotic in humans (
Route of infection. Introduction of sporozoites via the bite of the presumptive tick vector; possibly also via blood transfusion and solid organ transplants (
Site in human host. Blood.
Babesia microti (França, 1910)
Geographic distribution. Northeastern North America, Australia (
Natural hosts. Intermediate hosts are rodents, primarily white-footed mice (Peromyscus leucopus), and deer, primarily white-tailed deer (Odocoileus virginianus). Arthropod vector and definitive hosts are ticks in the genus Ixodes, primarily I. scapularis. Zoonotic in humans as intermediate hosts (
Route of infection. Introduction of sporozoites via the bite of infected tick, blood transfusion, and solid organ transplants (
Site in human host. Blood (
Babesia motasi Wenyoun, 1926
Babesia sp. Strain KO-1
Babesia ovis-like
Geographic distribution. Eurasia (
Natural hosts. Intermediate hosts are sheep. Definitive hosts are ticks in the genus Haemaphysalis. Zoonotic in humans as intermediate hosts (
Route of infection. Introduction of sporozoites via the bite of infected tick (
Site in human host. Blood (
Babesia odocoilei Emerson & Wright, 1970
Geographic distribution. Eastern North America (
Natural hosts. Intermediate hosts are cervids, primarily white-tailed deer (Odocoileus virginianus). Arthropod vector and definitive host is the tick Ixodes scapularis; birds may serve as reservoir hosts for larvae or nymphs. Zoonotic in humans as intermediate hosts (
Route of infection. Introduction of sporozoites via the bite of infected tick (
Site in human host. Blood (
Babesia venatorum
Babesia strain EU1
Geographic distribution. Europe (
Natural hosts. Intermediate hosts are red deer (Cervus elaphus); roe deer, sheep, dogs, cats, and other mammals may serve as reservoir hosts. Arthropod vectors and definitive hosts are ticks in the genus Ixodes, primarily I. ricinus. Zoonotic in humans as intermediate hosts (
Route of infection. Introduction of sporozoites via the bite of infected Ixodes tick; possibly also via blood transfusion and solid organ transplants (
Site in human host. Blood (
Babesia sp. Strain MO-1
Babesia divergens-like
Geographic distribution. Central and Pacific Northwest USA (
Natural hosts. Unknown; presumed intermediate hosts are unknown and presumed arthropod vector and definitive hosts are ticks in the genus Ixodes. Zoonotic in humans as intermediate hosts (
Route of infection. Introduction of sporozoites via the bite of infected tick; possibly also via blood transfusion and solid organ transplantation (
Site in human host. Blood (
Notes. This strain was originally described from Missouri, USA. It has since been described from the states of Washington, Kentucky, and Arkansas (
Babesia sp. crassa -like
Geographic distribution. Undefined; human cases known from China and Slovenia (
Natural hosts. Unknown; presumed intermediate hosts are sheep, goats, presumed arthropod vector and definitive hosts are ticks in the genera Haemaphysalis and/or Ixodes. Zoonotic in humans as intermediate hosts (
Route of infection. Introduction of sporozoites via the bite of infected tick; possibly also via blood transfusion and solid organ transplantation (
Site in human host. Blood (
●●●●● Anthemosomatidae Levine, 1981
Genus Anthemosoma Landau et al., 1969
Anthemosoma garnhami Landau et al., 1969
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Intermediate hosts are rodents, including spiny mice (Acomys). Arthropod vector and definitive hosts are unknown but presumed to be ixodid ticks. Zoonotic in humans (
Route of infection. Presumably by introduction of sporozoites via the bite of an infected tick (
Site in human host. Blood (
●●● Conoidasida Levine, 1988
●●●● Coccidia Leuckart, 1879
●●●●● Eimeriorina Léger, 1911
●●●●●● Eimeriidae Minchin, 1903
Genus Cyclospora Schneider, 1881
Cyclospora cayetanensis Ortega et al., 1994
Geographic distribution. Nearly worldwide, hot spots of endemicity include Latin America, the Caribbean, Middle East, and Southeast Asia (
Natural host. Human (
Route of infection. Ingestion of sporulated oocysts in fecally contaminated produce and water (
Site in human host. Small intestine (
●●●●●● Sarcocystidae Poche, 1913
Genus Cystoisospora Frenkel, 1977
Cystoisospora belli (Wenyon, 1923)
Geographic distribution. Nearly worldwide, more prevalent in tropics and subtropics (
Natural host. Human (
Route of infection. Ingestion of sporulated oocysts in fecally contaminated water, food, fomites (
Site in human host. Small intestine (
Genus Sarcocystis Lankester, 1882
Sarcocystis heydorni
Geographic distribution. Europe, China (
Natural hosts. Cattle are intermediate hosts. Humans are the definitive hosts (
Route of infection. Ingestion of cysts (bradyzoites) in undercooked beef (
Site in human host. Small intestine (
Sarcocystis hominis (Railiet & Lucet, 1891)
Sarcocystis bovihominis Heydorn et al., 1975
Geographic distribution. Nearly worldwide, more prevalent in tropics and subtropics (
Natural hosts. Intermediate hosts are cattle. Definitive hosts are humans and non-human primates (
Route of infection. Ingestion of cysts (bradyzoites) in undercooked beef (
Site in human host. Small intestine (
Sarcocystis nesbitti Mandour, 1969
Geographic distribution. Southeast Asia (
Natural hosts. Unknown. Natural intermediate host is unknown, non-human primates can serve as intermediate or reservoir hosts. Definitive hosts are presumed to be snakes or other reptiles. Zoonotic in humans as incidental intermediate hosts (
Route of infection. Ingestion of fully-sporulated oocysts in contaminated food, water, fomites (
Site in human host. Skeletal muscle (
Sarcocystis suihominis Heydorn, 1977
Geographic distribution. Nearly worldwide, more prevalent in tropics and subtropics (
Natural hosts. Intermediate hosts are pigs. Definitive hosts are humans and non-human primates (
Route of infection. Ingestion of cysts (bradyzoites) in undercooked pork (
Site in human host. Small intestine (
Genus Toxoplasma Nicolle & Manceaux, 1909
Toxoplasma gondii (Nicolle & Manceaus, 1908)
Geographic distribution. Worldwide (
Natural hosts. Wild and domestic felids. Many mammals and birds can serve as reservoir hosts; zoonotic in humans as dead-end hosts (
Route of infection. Ingestion of fully sporulated oocysts in food, water, fomites contaminated with cat feces; ingestion of cysts (bradyzoites) in infected paratenic hosts; blood transfusion or solid organ transplantation; transplacentally from mother to fetus (
Site in human host. Disseminated infection, common sites are skeletal muscle, myocardium, brain, and eyes; can be transmitted transplacentally from mother to fetus (
●●●● Gregarinasina Dufour, 1828
●●●●● Cryptogregarinorida Cavalier-Smith, 2014, emend.
●●●●●● Cryptosporidiidae Leger, 1911
Genus Cryptosporidium Tyzzer, 1910
Cryptosporidium andersoni Lindsay et al., 2000
Geographic distribution. Worldwide (
Natural hosts. Cattle, camels, sheep, goats, horses. Zoonotic in humans (
Route of infection. Ingestion of sporulated oocysts in water, food, fomites contaminated with animal feces (
Site in human host. Unknown, presumed stomach.
Cryptosporidium bovis Barker & Carbonell, 1974
Geographic distribution. Worldwide (
Natural hosts. Cattle. Zoonotic in humans (
Route of infection. Ingestion of sporulated oocysts in water, food, fomites contaminated with cattle feces (
Site in human host. Duodenum and small intestine.
Cryptosporidium canis
Geographic distribution. Worldwide (
Natural hosts. Dogs. Zoonotic in humans (
Route of infection. Ingestion of sporulated oocysts in water, food, fomites contaminated with dog feces (
Site in human host. Duodenum and small intestine
Cryptosporidium cuniculus Inman & Takeuchi, 1979
Geographic distribution. Undefined, most human cases from Europe and Australia (
Natural hosts. Rabbits, kangaroos. Zoonotic in humans (
Route of infection. Ingestion of sporulated oocysts water, food, fomites contaminated with rabbit/animal feces (
Site in human host. Duodenum and small intestine.
Cryptosporidium ditrichi Čondlová et al., 2018
Geographic distribution. Europe (
Natural hosts. Field mice (Apodemus spp.). Zoonotic in humans (
Route of infection. Ingestion of sporulated oocysts in water, food, fomites contaminated with rodent feces (
Site in human host. Duodenum and small intestine
Cryptosporidium erinacei
Cryptosporidium hedgehog genotype
Geographic distribution. Europe (
Natural hosts. Hedgehogs, horses. Zoonotic in humans (
Route of infection. Ingestion of sporulated oocysts in water, food, fomites contaminated with animal feces (
Site in human host. Duodenum and small intestine
Cryptosporidium fayeri
Geographic distribution. Australia (
Natural hosts. Marsupials. Zoonotic in humans (
Route of infection. Ingestion of sporulated oocysts in water, food, fomites contaminated with marsupial feces (
Site in human host. Duodenum and small intestine
Cryptosporidium felis Iseki, 1979
Geographic distribution. Worldwide (
Natural hosts. Cats, foxes, horses, cattle. Zoonotic in humans (
Route of infection. Ingestion of sporulated oocysts in fecally contaminated water, food, fomites contaminated with cat/animal feces (
Site in human host. Duodenum and small intestine
Cryptosporidium hominis Morgan-Ryan et al., 2002
Geographic distribution. Worldwide (
Natural hosts. Humans, non-human primates (
Route of infection. Ingestion of sporulated oocysts in water, food, fomites contaminated with human feces (
Site in human host. Duodenum and small intestine, disseminated infections in immunocompromised patients (
Cryptosporidium meleagridis Slavin, 1955
Geographic distribution. Worldwide
Natural hosts. Birds. Zoonotic in humans (
Route of infection. Ingestion of sporulated oocysts in fecally contaminated water, food, fomites contaminated with bird feces (
Site in human host. Duodenum and small intestine, disseminated infections in immunocompromised patients (
Cryptosporidium muris Tyzzer, 1910
Geographic distribution. Worldwide (
Natural hosts. Rodents, ruminants, horses, non-human primates, carnivores. Zoonotic in humans (
Route of infection. Ingestion of sporulated oocysts in water, food, fomites contaminated with animal feces (
Site in human host. Unknown, presumed stomach (
Cryptosporidium occultus Kváč et al., 2018
Cryptosporidium parvum VF383
Geographic distribution. Worldwide (
Natural hosts. Rodents. Zoonotic in humans (
Route of infection. Ingestion of sporulated oocysts in water, food, fomites contaminated with rodent feces (
Site in human host. Duodenum and small intestine
Cryptosporidium parvum Tyzzer, 1912
Geographic distribution. Worldwide (
Natural hosts. Cattle, sheep, goats, and other ruminants, rodents. Zoonotic in humans (
Route of infection. Ingestion of sporulated oocysts in water, food, fomites contaminated with human and animal feces (
Site in human host. Duodenum and small intestine, disseminated infections in immunocompromised patients (
Cryptosporidium ryanae
Cryptosporidium deer-like genotype
Geographic distribution. XX (
Natural hosts. Cattle. Zoonotic in humans (
Route of infection. Ingestion of sporulated oocysts in water, food, fomites contaminated with cattle feces (
Site in human host. Duodenum and small intestine.
Cryptosporidium scrofarum
Cryptosporidium pig genotype II
Geographic distribution. Worldwide (
Natural hosts. Pigs. Zoonotic in humans (
Route of infection. Ingestion of sporulated oocysts in water, food, fomites contaminated with pig feces (
Site in human host. Duodenum and small intestine.
Cryptosporidium suis
Geographic distribution. Worldwide (
Natural hosts. Pigs. Zoonotic in humans (
Route of infection. Ingestion of sporulated oocysts in water, food, fomites contaminated with pig feces (
Site in human host. Duodenum and small intestine
Cryptosporidium tyzzeri Ren et al., 2012
Cryptosporidium mouse genotype I
Geographic distribution. Presumed worldwide (
Natural hosts. Rodents, horses may serve as reservoir hosts. Zoonotic in humans (
Route of infection. Ingestion of sporulated oocysts in water, food, fomites contaminated with rodent feces (
Site in human host. Duodenum and small intestine
Cryptosporidium ubiquitum Fayer et al., 2010
Cryptosporidium cervine genotype
Geographic distribution. Worldwide (
Natural hosts. Many mammal species, including ruminants, rodents, and carnivores; presumed zoonotic in humans (
Route of infection. Ingestion of sporulated oocysts in water, food, fomites contaminated with animal feces (
Site in human host. Duodenum and small intestine
Cryptosporidium viatorum Elwin et al., 2012
Geographic distribution. Worldwide (
Natural hosts. Rodents. Zoonotic in humans (
Route of infection. Ingestion of sporulated oocysts in water, food, fomites contaminated with rodent and human feces (
Site in human host. Duodenum and small intestine.
●●● Postodesmatophora Gerassimova & Seravin, 1976
●●●● SAL (Spirotrichea-Lamellicorticata-Armophorea) Gentekaki et al., 2014
●●●●● Litostomatea Small & Lynn, 1981
●●●●●● Trichostomatia Bütschli, 1889
●●●●●●● Balantidiidae Reichenow in Doflein & Reichenow, 1929
Genus Balantioides Alexeieff, 1931
Neobalantidium Pomajbíková et al., 2013
Balantioides coli (Malmsten, 1857)
Geographic distribution. Worldwide; high areas of endemicity include the Altiplano region of Bolivia, Philippines, New Guinea, Middle East (
Natural hosts. Pigs, rodents. Zoonotic in humans (
Route of infection. Ingestion of mature cysts in fecally contaminated water, food, fomites (
Site in human host. Large intestine (
●●● Diplomonadida Wenyon, 1926
●●●● Hexamitidae Kent, 1880
Genus Enteromonas da Fonseca, 1915
Enteromonas hominis da Fonseca, 1915
Tricercomonas intestinalis Wenyon et O’Connor, 1917
Geographic distribution. Worldwide (
Natural host. Humans (
Route of infection. Ingestion of mature cysts in fecally contaminated water, food, fomites (
Site in human host. Large intestine (
Genus Giardia Künstler, 1882
Giardia duodenalis Stiles, 1902
Cercomonas intestinalis Lambl, 1859
Giardia lamblia Kofoid & Christiansen, 1915
Giardia enterica Kofoid & Christiansen, 1920
Geographic distribution. Worldwide (
Natural hosts. Two genetic assemblages implicated in human disease: A and B. Both have been found in humans and numerous non-human mammals and birds (
Route of infection. Ingestion of mature cysts in fecally contaminated water, food, fomites; sexual transmission via oral-anal route (
Site in human host. Duodenum, small intestine (
●●● Retortamonadida Grassé, 1952
●●●● Retortamonadidae Wenrich, 1932
Genus Chilomastix Alexeieff, 1912
Chilomastix mesnili (Wenyon, 1910)
Geographic distribution. Worldwide (
Natural hosts. Humans, non-human primates (
Route of infection. Ingestion of mature cysts in fecally contaminated water, food, fomites (
Site in human host. Large intestine (
Genus Retortamonas Grassi, 1879
Retortamonas intestinalis (Wenyon et O’Connoer, 1917)
Geographic distribution. Worldwide (
Natural host. Humans (
Route of infection. Ingestion of mature cysts in fecally contaminated water, food, fomites (
Site in human host. Large intestine (
●●● Trichonomadida Kirby, 1947
●●●● Monocercomonadidae Kirby, 1944
Genus Dientamoeba Jepps & Dobell, 1918
Dientamoeba fragilis Jepps & Dobell, 1918
Geographic distribution. Worldwide (
Natural hosts. Humans, non-human primates, pigs (
Route of infection. Ingestion of trophozoites in fecally contaminated water, food, fomites. A putative cyst stage has been described, but it is not yet widely accepted among protozoologists (
Site in human host. Large intestine (
●●●● Trichomonadidae Chalmers & Pekkola, 1918, emend. Hampl et al., 2004
Genus Pentatrichomonas Mensil, 1914
Pentatrichomonas hominis (Davaine, 1860)
Geographic distribution. Worldwide (
Natural hosts. Humans, non-human primates, dogs, cats, foxes, rabbits, cattle, sheep, goats, deer (
Route of infection. Ingestion of trophozoites in fecally contaminated fomites (
Site in human host. Large intestine (
Genus Trichomonas Donné, 1837
Trichomonas tenax (Müller, 1773)
Geographic distribution. Worldwide (
Natural host. Humans (
Route of infection. Direct person-to-person contact (
Site in human host. Oral cavity; ectopic colonization of pleural cavity (
Trichomonas vaginalis (Donné, 1836)
Geographic distribution. Worldwide (
Natural host. Humans (
Route of infection. Sexual contact (
Site in human host. Urogenital tract; rare ectopic colonization of CSF (
Genus Tritrichomonas Kofoid, 1920
Tritrichomonas foetus Reidmüller, 1928
Trichomonas suis Gruby & Delafond, 1843
Geographic distribution. Worldwide (
Natural host. Cattle, pigs, cats. Zoonotic and opportunistic in immunocompromised humans (
Route of infection. Unknown.
Site in human host. Respiratory tract, CNS, urogenital tract (
Genus Tetratrichomonas Parisi, 1910
Tetratrichomonas sp. cf. gallinarum
Geographic distribution. Unknown, presumed worldwide
Natural host. Unknown, presumed birds. Zoonotic in humans (
Route of infection. Unknown
Site in human host. Respiratory tract, possibly associated with bacterial infection (
Notes. This species has yet to be formally described. It was first isolated from pleural fluid in a patient with empyema. Bacterial cultures of the pleural fluid grew two Streptococcus species and Prevotella (
Tetratrichomonas sp. (undescribed species)
Tetratrichomonas empyemagena
Geographic distribution. Unknown, presumed worldwide
Natural hosts. Unknown
Route of infection. Unknown
Site in human host. Respiratory tract (
Notes. This species was reported from two patients from Mexico(
●●●● Simplicimonadidae Čepička et al., 2010
Genus Simplicimonas Čepička et al., 2010
Simplicimonas similis Čepička et al., 2010
Geographic distribution. Undefined, possibly worldwide (
Natural hosts. Several vertebrates; previously recorded from lizards, cattle, and chickens (
Route of infection. Unknown.
Site in human host. Intestinal tract (
Notes. Simplicimonas similis was detected by molecular methods in four human patients in Madagascar (
●●● Tetramitia Cavalier-Smith, 1993
●●●● Vahlkampfiidae Jollos, 1917
Genus Naegleria Alexeieff, 1912
Naegleria fowleri Carter, 1970
Geographic distribution. Worldwide (
Natural host. None (environmental); humans are incidental hosts (
Route of infection. Exposure to trophozoites and cysts in contaminated freshwater via the nasal cavity; improper use of nasal irrigation devices (
Site in human host. CNS (
Genus Paravahlkampfia Brown et de Jonckheere, 1999
Paravahlkampfia francinae
Geographic distribution. Unknown (single case from Ohio, USA) (
Natural host. None (environmental); humans are incidental hosts (
Route of infection. Unknown; presumed environmental exposure.
Site in human host. CNS (
Genus Tetramitus Perty, 1852
Tetramitus entericus (Page, 1974)
Geographic distribution. Worldwide (
Natural host. None (environmental); humans are incidental hosts (
Route of infection. Presumed environmental exposure.
Site in human host. Eye (
Tetramitus jugosus (Page, 1967)
Geographic distribution. Worldwide (
Natural host. None (environmental); humans are incidental hosts (
Route of infection. Presumed environmental exposure (
Site in human host. Eye (
Genus Vahlkampfia Chatton et Lalung-Bonnaire, 1912
Geographic distribution. Worldwide (
Natural host. None (environmental); humans are incidental hosts (
Route of infection. Unknown; presumed environmental exposure.
Site in human host. Eye (
Notes. Most reports of Vahlampfia from human clinical specimens are not characterized at the species level and may represent species currently assigned to other genera such as Tetramitus, Allovahlkampfia, and Paravahlkampfia.
●●●● Acrasidae Poche, 1913
Genus Allovahlkampfia Walochnik & Mulec, 2009
Allovahlkampfia spelaea Walochnik & Mulec, 2009
Geographic distribution. Not fully known; described from caves in Slovenia with single human case from Egypt (Walochnik 2009;
Natural host. None (environmental); humans are incidental hosts (
Route of infection. Unknown; presumed environmental exposure.
Site in human host. Eye (
●●● Kinetoplastea Honigberg, 1963
●●●● Metakinetoplastina Vickerman in Moreira et al., 2004
●●●●● Trypanosomatida Kent 1880, emend. Vickerman in Moreira et al. 2004
●●●●●● Trypanosomatidae Doflein, 1901
Genus Crithidia Léger, 1902
Geographic distribution. Worldwide (
Natural hosts. Arthropods, mainly insects. Zoonotic in humans (
Route of infection. Introduction of promastigotes via the bite of infected arthropod vector (
Site in human host. Skin, bone marrow (
Notes. Crithidia isolates from human clinical specimens have yet to be characterized at the species level. To date, cases are known from Brazil (
Genus Endotrypanum Mesnil & Brimont, 1908
Endotrypanum colombiensis (Kreuter et al., 1991)
Geographic distribution. Colombia (
Natural hosts. Mammalian hosts are sloths; zoonotic in humans. Arthropod vectors are sand flies in the genus Lutzomyia (
Route of infection. Introduction of promastigotes via the bite of infected Lutzomyia sand fly (
Site in human host. Skin (
Endotrypanum equatoriensis (
Geographic distribution. Colombia, Ecuador (
Natural hosts. Mammalian hosts are sloths and squirrels; zoonotic in humans. Arthropod vectors are sand flies in the genus Lutzomyia (
Route of infection. Introduction of promastigotes via the bite of infected Lutzomyia sand fly (
Site in human host. Skin (
Genus Leishmania Ross, 1903
Euleishmania Cupolillo et al., 2000
Subgenus Leishmania Ross, 1903
Leishmaniai (L .) aethiopica
Geographic distribution. Africa (Ethiopia, Kenya, Uganda), Yemen (
Natural hosts. Mammalian hosts include humans, rock hyraxes, and other wild mammals. Arthropod vectors are sand flies in the genus Phlebotomus, mainly P. longipes and P. pedifer (
Route of infection. Introduction of promastigotes via the bite of infected Phlebotomus sand fly (
Site in human host. Skin (
Leishmania (L.) amazonensis Lainson & Shaw, 1972
Leishmania garnhami Scorza et al., 1978
Geographic distribution. Amazonian South America (Brazil, Venezuela, Bolivia) (
Natural hosts. Mammals and birds, including humans, rodents, dogs, chickens. Arthropod vectors are sand flies in the genus Lutzomyia (
Route of infection. Introduction of promastigotes via the bite of infected Lutzomyia sand fly (
Site in human host. Skin, mucosal membranes of nose, throat, and mouth (
Leishmania (L.) donovani (Laveran & Mesnil, 1903)
Leishmania archibaldi Castellani & Chalmers, 1919
Geographic distribution. Indian subcontinent, China, Central Africa; hot spots of endemicity include India, Bangladesh, Nepal, Sudan (
Natural hosts. Mammalian hosts include humans, dogs, foxes, marsupials, and rodents. Arthropod vectors are sand flies in the genera Phlebotomus (Old World) and Lutzomyia (New World) (
Route of infection. Introduction of promastigotes via the bite of infected sand fly (
Site in human host. Skin, spleen, liver, small intestine, lymph nodes (
Leishmania (L.) infantum Nicolle, 1908
Leishmania chagasi da Cunha & Chagas, 1937
Geographic distribution. Mediterranean Europe and Africa, southeastern Europe, Middle East, Central Asia, Central and South America (Mexico, Venezuela, Brazil, Bolivia) (
Natural hosts. Mammalian hosts include dogs, cats, foxes, lagomorphs, rodents, marsupials, and others; zoonotic in humans. Arthropod vectors are sand flies in the genera Phlebotomus (Old World) and Lutzomyia (New World) (
Route of infection. Introduction of promastigotes via the bite of infected sand fly (
Site in human host. Skin, spleen, liver, small intestine, lymph nodes (
Leishmania (L.) major Yakimoff & Schokhor, 1914
Geographic distribution. Northern and Central Africa, Middle East, India, China (
Natural hosts. Humans; gerbils and birds may serve as reservoir hosts; dogs can become infected but are not adequate reservoir hosts for human disease. Arthropod vectors are sand flies in the genus Phlebotomus (
Route of infection. Introduction of promastigotes via the bite of infected Phlebotomus sand fly (
Site in human host. Skin (
Leishmania (L.) mexicana Biagi, 1953, emend. Garnham, 1962
Leishmania pifanoi Medina & Romero, 1962
Geographic distribution. Texas, Mexico, Belize, Guatemala, Brazil, Ecuador, Peru, Venezuela (
Natural hosts. Mammalian hosts include humans, dogs, rodents, and bats. Arthropod vectors are sand flies in the genus Lutzomyia (
Route of infection. Introduction of promastigotes via the bite of infected sand fly (
Site in human host. Skin (
Leishmania (L.) tropica Wright, 1903
Geographic distribution. North and Central Africa, Middle East, Central Asia, India (
Natural hosts. Mammalian hosts include humans, rock hyraxes, gundi, and dogs (although dogs are not an adequate reservoir host for human disease). Arthropod vectors are sand flies in the genus Phlebotomus (
Route of infection. Introduction of promastigotes via the bite of infected sand fly (
Site in human host. Skin (
Leishmania (L.) venezuelensis (Bonfante-Garrido, 1980)
Geographic distribution. Venezuela, northern South America (
Natural hosts. Mammalian hosts include humans, cats. Arthropod vectors are sand flies in the genus Lutzomyia (
Route of infection. Introduction of promastigotes via the bite of infected Lutzomyia sand fly (
Site in human host. Skin (
Leishmania (L .) waltoni
Geographic distribution. Dominican Republic (
Natural hosts. Mammalian hosts unknown, rats may serve as reservoir hosts; presumed zoonotic in humans. Arthropod vectors are sand flies in the genus Lutzomyia (
Route of infection. Introduction of promastigotes via the bite of infected Lutzomyia sand fly (
Site in human host. Skin (
Subgenus Mundinia Shaw et al. in Espinosa et al., 2016
Leishmania (M.) martiniquensis
Geographic distribution. Martinique, Thailand (
Natural hosts. Mammalian hosts are humans. Rats may serve as reservoir hosts. Arthropod vectors are sand flies, possibly in the genera Sergentomyia (Old World) and Lutzomyia (New World) (
Route of infection. Introduction of promastigotes via the bite of infected sand fly
Site in human host. Skin, mucosal membranes of nose, throat, and mouth (
Leishmania (M.) orientalis
Leishmania siamensis
Geographic distribution. Thailand (
Natural hosts. Mammalian hosts are humans. Arthropod vectors are sand flies. (
Route of infection. Introduction of promastigotes via the bite of infected sand fly (genus unknown).
Site in human host. Skin (
Subgenus Sauroleishmania Ranque, 1973
Leishmania (S.) tarentolae Weynon, 1921
Geographic distribution. North Africa, southern Europe, Middle East (
Natural hosts. Definitive hosts are lizards. Arthropod vectors are sand flies in the genus Sergentomyia. Zoonotic in humans (
Route of infection. Introduction of promastigotes in bite of infected Sergentomyia sand fly (
Site in human host. Blood (
Notes. The single human case was diagnosed by molecular detection (only) in blood (
Subgenus Viannia Lainson & Shaw, 1987
Leishmania (V.) braziliensis Vianna, 1911
Geographic distribution. Amazonian South America (Brazil, Bolivia, Venezuela, Peru), Guatemala (
Natural hosts. Mammalian hosts include humans, dogs, rodents, and marsupials. Arthropod vectors are sand flies in the genus Lutzomyia (
Route of infection. Introduction of promastigotes via the bite of infected Lutzomyia sand fly (
Site in human host. Skin, mucosal membranes of nose, throat, and mouth (
Leishmania (V.) guyanensis Floch, 1954
Geographic distribution. Northern South America (French Guiana, Suriname, Brazil, Bolivia) (
Natural hosts. Mammalian hosts include sloths, anteaters, rodents, marsupials, and humans. Arthropod vectors are sand flies in the genus Lutzomyia (
Route of infection. Introduction of promastigotes via the bite of infected Lutzomyia sand fly (
Site in human host. Skin, mucosal membranes of nose, throat, and mouth (
Leishmania (V.) lainsoni Silveira et al., 1987
Geographic distribution. Brazil, Bolivia, Ecuador, Peru, Suriname, French Guiana (
Natural hosts. Mammalian host is lowland paca; zoonotic in humans. Arthropod vectors are sand flies in the genus Lutzomyia (
Route of infection. Introduction of promastigotes via the bite of infected Lutzomyia sand fly (
Site in human host. Skin (
Leishmania (V .) lindenbergi Silveira et al., 2002
Geographic distribution. Brazil (
Natural hosts. Mammalian hosts unknown; presumed zoonotic in humans. Arthropod vectors are sand flies in the genus Lutzomyia (
Route of infection. Introduction of promastigotes via the bite of infected Lutzomyia sand fly (
Site in human host. Skin (
Leishmania (V.) naiffi Lainson & Shaw, 1989
Geographic distribution. Brazil, Bolivia, Peru (
Natural hosts. Mammalian hosts are armadillos; zoonotic in humans. Arthropod vectors are sand flies in the genus Lutzomyia (
Route of infection. Introduction of promastigotes via the bite of infected Lutzomyia sand fly (
Site in human host. Skin (
Leishmania (V.) panamensis Lainson & Shaw, 1972
Geographic distribution. Central and South America (
Natural hosts. Mammalian hosts include sloths, procyonids, rodents, humans, and non-human primates. Arthropod vectors are sand flies in the genus Lutzomyia (
Route of infection. Introduction of promastigotes via the bite of infected Lutzomyia sand fly (
Site in human host. Skin, mucosal membranes of nose, throat, and mouth (
Leishmania (V.) peruviana Velez, 1913
Geographic distribution. Peru, Bolivia (
Natural hosts. Mammalian hosts include humans, rodents, marsupials, and domestic dogs. Arthropod vectors are sand flies in the genera Lutzomyia and possibly Pintomyia (
Route of infection. Introduction of promastigotes via the bite of infected sand fly (
Site in human host. Skin, mucosal membranes of nose, throat, and mouth (
Leishmania (V.) shawi
Geographic distribution. Brazil (
Natural hosts. Mammalian hosts include non-human primates, sloths, coati; zoonotic in humans. Arthropod vectors are sand flies in the genus Lutzomyia (
Route of infection. Introduction of promastigotes via the bite of infected Lutzomyia sand fly (
Site in human host. Skin (
Genus Leptomonas Kent, 1880
Leptomonas seymouri (Wallace, 1877)
Geographic distribution. Worldwide (
Natural hosts. Insects. Zoonotic in humans (
Route of infection. Presumed introduction of promastigotes via the bite of infected Phlebotomus sand flies (
Site in human host. Skin, spleen, bone marrow (
Notes. Human cases of L. seymouri to date have been found in Southeast Asia associated with co-infection with Leishmania donovani, suggesting incidental human infection after the bite of an infected sand fly vector.
Genus Trypanosoma Gruby, 1843
Subgenus Herpetosoma Doflein, 1901
Trypanosoma (H.) lewisi Laveran & Mesnil, 1901
Geographic distribution. Cosmopolitan (
Natural hosts. Mammalian hosts are rats (Rattus spp.); zoonotic in humans. Arthropod vectors are rat fleas Nosophyllus fasciatus and Xenopsylla cheopis (
Route of infection. Ingestion of infected fleas or their feces (
Site in human host. Blood (
Trypanosoma (H.) rangeli Tejera, 1920
Trypanosoma saimirii Rodhain, 1941
Geographic distribution. South America (
Natural hosts. Mammalian hosts include coati, sloths, tamandua, and opossums; zoonotic in humans. Arthropod vectors are triatomine bugs, most-notably members of the genus Rhodnius (
Route of infection. Introduction of trypomastigotes via the bite of infected triatomine bug (
Site in human host. Blood (
Subgenus Schizotrypanum Chagas, 1909
Trypanosoma (S.) cruzi Chagas, 1909
Geographic distribution. Southern United States, Central and South America (
Natural hosts. Mammalian hosts include humans and many domestic and wild mammals. Arthropod vectors are triatomine bugs, most-notably members of the genera Triatoma, Panstrongylus, and Rhodnius (
Route of infection. Introduction of metacyclic trypomastigotes in the feces of infected triatomine bug when rubbed into wounds or mucus membranes; ingestion of food contaminated with bugs or their feces; transplacentally from mother to fetus; via blood transfusion and organ transplantation (
Site in human host. Blood (acute infection, reactivation); heart muscle, esophagus, large intestine, peripheral nervous system, CNS, other organs (chronic infection) (
Subgenus Trypanozoon Lühe, 1906
Trypanosoma (T.) brucei gambiense (Dutton, 1902)
Geographic distribution. West-central Africa; hot spots of endemicity include Angola, Democratic Republic of Congo, South Sudan, Central African Republic, Uganda (
Natural hosts. Mammalian hosts include humans, non-human primates, and ungulates. Arthropod vectors are tsetse flies in the genus Glossina (
Route of infection. Introduction of trypomastigotes via the bite of infected Glossina tsetse fly (
Site in human host. Blood, lymphatics, CNS (
Trypanosoma (T.) brucei rhodesiense (Stephen & Fantham, 1910)
Geographic distribution. East and southeast Africa; hot spots of endemicity include Malawi, Zambia, Tanzania, Botswana, Kenya (
Natural hosts. Mammalian hosts include livestock and wild ungulates; zoonotic in humans. Arthropod vectors are tsetse flies in the genus Glossina (
Route of infection. Introduction of trypomastigotes via the bite of infected Glossina tsetse fly (
Site in human host. Blood, lymphatics, CNS (
Trypanosoma (T.) evansi Balbiani, 1888
Geographic distribution. Equatorial regions of Africa, Asia, Latin America (
Natural hosts. Mammalian hosts include horses, camels, bovids; zoonotic in humans. Arthropod vectors are biting flies in the genera Stomoxys and Tabanus (
Route of infection. Introduction of trypomastigotes via the bite of infected flies; possibly direct contact with blood/wounds of infected animals (
Site in human host. Blood (
●●● Protostomia Grobben, 1908
●●●● Spiralia Edgecombe et al., 2011
●●●●● Acanthocephala Koelreuther, 1771
●●●●●● Oligacanthorhynchida Petrotschenko, 1956
●●●●●●● Oligacanthorhynchidae Southwell & Macfie, 1925
Genus Macracanthorhynchus Travassos, 1917
Macracanthorhynchus hirudinaceus (Pallas, 1781)
Taenia haeruca Pallas, 1776
Echinorhynchus gigas Bloch, 1782
Geographic distribution. Worldwide (
Natural hosts. Intermediate hosts are insects, primarily scarabaeoid beetles. Definitive hosts are pigs; dogs and other mammals can serve as reservoir hosts. Zoonotic in humans (
Route of infection. Ingestion of cystacanths in infected insect intermediate host (
Site in human host. Small intestine (
Macracanthorhynchus ingens (von Linstow, 1879)
Geographic distribution. Eastern North America (
Natural hosts. Intermediate hosts are millipedes. Definitive hosts are raccoons (Procyon lotor) and American black bear (Ursus americanus); many other mammals, especially carnivores, can serve as definitive hosts. Snakes and other animals may serve as paratenic hosts. Zoonotic in humans (
Route of infection. Ingestion of cystacanths in infected arthropod intermediate host or paratenic hosts (
Site in human host. Small intestine (
●●●●●● Moniliformida Schmidt, 1972
●●●●●●● Moniliformidae Van Cleave, 1924
Genus Moniliformis Travassos, 1915
Moniliformis moniliformis (Bremser, 1811)
Echinorhynchus grassi Railliet, 1893
Echinorhynchus canis Porta, 1914
Echinorhynchus belgicus Railliet, 1918
Moniliformis moniliformis siciliensis Meyer, 1932
Moniliformis moniliformis agypticus Meyer, 1932
Moniliformis dubius Meyer, 1932
Geographic distribution. Worldwide (
Natural hosts. Intermediate hosts are insects, primarily beetles and cockroaches. Definitive hosts are primarily rodents and carnivores. Zoonotic in humans (
Route of infection. Ingestion of cystacanths in infected insect intermediate host (
Site in human host. Small intestine (
●●●●●● Echinorhynchida Petrotschenko, 1956
●●●●●●● Echinorhynchidae Cobbold, 1876
Genus Acanthocephalus Koelreuther, 1771
Acanthocephalus rauschi (Schmidt, 1969)
Geographic distribution. Alaska (
Natural hosts. Alaskan grayling (Thymallus arcticus). Otters can serve as paratenic hosts. Zoonotic in humans (
Route of infection. Unknown; presumed ingestion of cystacanths in infected intermediate host.
Site in human host. Peritoneum (
Genus Pseudoacanthocephalus Petrotschenko, 1958
Pseudoacanthocephalus bufonis (Shipley, 1903)
Acanthocephalus sinensis Van Cleave, 1937
Geographic distribution. Southeast Asia, Hawaii (
Natural hosts. Toads. Zoonotic in humans (
Route of infection. Unknown; presumed ingestion of cystacanths in infected intermediate host.
Site in human host. Small intestine (
●●●●●● Polymorphida Petrotschenko, 1956
●●●●●●● Polymorphidae Meyer, 1931
Genus Bolbosoma Porta, 1908
Bolbosoma nipponicum Yamaguti, 1939
Geographic distribution. North Atlantic (
Natural hosts. Marine crustaceans serve as intermediate hosts. Fish and cephalopods may serve as paratenic hosts. Whales and seals serve as definitive hosts. Zoonotic in humans (
Route of infection. Unknown; presumed ingestion of cystacanths in infected fish paratenic hosts.
Site in human host. Small intestine (
Bolbosoma sp. cf. capitatum (von Linstow, 1880)
Geographic distribution. Worldwide (
Natural hosts. Marine crustaceans serve as intermediate hosts. Whales serve as definitive hosts. Zoonotic in humans (
Route of infection. Unknown; presumed ingestion of cystacanths in infected fish paratenic hosts.
Site in human host. Small intestine (
Notes. The single case was reported from Japan as Bolbosoma cf. capitatim based on molecular and histological examination (
Genus Corynosoma Lühe, 1904
Corynosoma strumosum (Rudolphi, 1802)
Geographic distribution. Worldwide (
Natural hosts. Intermediate hosts are marine amphipods. Several groups of fish may serve as paratenic hosts. Definitive hosts are seals, walrus, beluga whale. Zoonotic in humans (
Route of infection. Ingestion of cystacanths in infected fish paratenic host (
Site in human host. Small intestine (
Corynosoma villosum Van Cleave, 1953
Geographic distribution. North Pacific (
Natural hosts. Intermediate hosts are marine amphipods. Several groups of fish may serve as paratenic hosts. Definitive hosts are pinnipeds and whales. Zoonotic in humans (
Route of infection. Ingestion of cystacanths in infected fish paratenic host (
Site in human host. Small intestine (
Corynosoma sp. cf. validum Van Cleave, 1953
Geographic distribution. North Pacific (
Natural hosts. Intermediate hosts are marine amphipods. Several groups of fish may serve as paratenic hosts. Definitive host is the northern fur seal (Callorhinus ursinus), and other pinnipeds. Zoonotic in humans (
Route of infection. Ingestion of cystacanths in infected fish paratenic host (
Site in human host. Small intestine (
Notes. The single case was reported from Japan as Corynosoma cf. validum based on DNA sequencing (
●●●●● Annelida Lamarck, 1802
●●●●●● Hirudinea Lamarck, 1818
●●●●●●● Rhynchobdellida Blanchard, 1894
●●●●●●●● Glossiphoniidae Vaillant, 1890
Genus Haementeria de Filippi, 1849
Haementeria acuecueyetzin Oceguera-Figueroa, 2008
Geographic distribution. Mexico (
Natural hosts. Various vertebrates. Zoonotic on humans (
Route of infection. Exposure to fresh water (
Site in human host. Skin (
Vectored pathogens. None.
Haementeria ghilianii de Filippi, 1849
Geographic distribution. Amazon South America (
Natural hosts. Various mammals. Zoonotic on humans (
Route of infection. Exposure to fresh water (Farrar 2014).
Site in human host. Skin (Farrar 2014).
Vectored pathogens. None.
Genus Parabdella Autrum, 1936
Parabdella quadrioculata (Moore, 1930)
Geographic distribution. East Asia (
Natural hosts. Freshwater turtles and frogs. Zoonotic on humans (
Route of infection. Exposure to fresh water (
Site in human host. Skin (
Vectored pathogens. None.
Genus Placobdella Blanchard, 1893
Placobdella costata (Müller, 1846)
Placobdella catenigera Moquin-Tandon, 1846
Geographic distribution. Mediterranean Region, Central Europe (
Natural hosts. Freshwater turtles. Zoonotic on humans (
Route of infection. Exposure to fresh water (Aloto 2018).
Site in human host. Skin (Aloto 2018).
Vectored pathogens. None.
●●●●●●● Hirudiniformes Caballero, 1952
●●●●●●●● Xerobdellidae Moore, 1946
Genus Diestecostoma Vaillant, 1890
Heterobdella Baird, 1869
Hygrobdella Caballero, 1940
Diestecostoma mexicana (Baird, 1869)
Geographic distribution. Central America (
Natural hosts. Various mammals. Zoonotic on humans (Farrar 2014).
Route of infection. Environmental exposure (Farrar 2014).
Site in human host. Skin (Farrar 2014).
Vectored pathogens. None.
●●●●●●●● Haemadipsidae Blanchard, 1896
Genus Haemadipsa Tennent, 1859
Haemadipsa hainana Song, 1977
Geographic distribution. Southeast Asia (
Natural hosts. Various mammals and birds. Zoonotic on humans (
Route of infection. Environmental exposure (
Site in human host. Skin (
Vectored pathogens. None.
Haemadipsa interrupta Moore, 1935
Geographic distribution. Southeast Asia (
Natural hosts. Various mammals and birds. Zoonotic on humans (
Route of infection. Environmental exposure (
Site in human host. Skin (
Vectored pathogens. None.
Haemadipsa japonica Whitman, 1886
Geographic distribution. East Asia (
Natural hosts. Various mammals, birds, amphibians. Zoonotic on humans (
Route of infection. Environmental exposure (
Site in human host. Skin, mucous membranes or the rectum and genital tract (
Vectored pathogens. None.
Haemadipsa picta Moore, 1929
Geographic distribution. Southeast Asia (
Natural hosts. Various large mammals, including humans (
Route of infection. Environmental exposure (
Site in human host. Skin (
Vectored pathogens. None.
Haemadipsa rjukjuana Oka, 1910
Geographic distribution. East Asia (
Natural hosts. Various mammals, including humans, and birds (
Route of infection. Environmental exposure (
Site in human host. Skin (
Vectored pathogens. None
Haemadipsa sylvestris Blanchard, 1894
Geographic distribution. Southeast Asia (Farrar 2014).
Natural hosts. Various mammals. Zoonotic on humans (Farrar 2014).
Route of infection. Environmental exposure (Farrar 2014).
Site in human host. Skin (Farrar 2014).
Vectored pathogens. None.
Haemadipsa trimaculosa
Geographic distribution. Southeast Asia (
Natural hosts. Various mammals and birds. Zoonotic on humans (
Route of infection. Environmental exposure (
Site in human host. Skin (
Vectored pathogens. None
Haemadipsa zeylanica (Moquin-Tandon, 1826)
Geographic distribution. Japan, Southeast Asia (
Natural hosts. Various amphibians and mammals. Zoonotic on humans (
Route of infection. Environmental exposure (
Site in human host. Skin (
Vectored pathogens. None.
Genus Phytobdella Blanchard, 1894
Phytobdella catenifera Moore, 1942
Geographic distribution. Malaysia (Farrar 2014).
Natural hosts. Reptiles. Zoonotic on humans (Farrar 2014).
Route of infection. Environmental exposure (Farrar 2014).
Site in human host. Skin (Farrar 2014).
Vectored pathogens. None.
●●●●●●●● Hirudinidae Whitman, 1886
Genus Hirudo Linnaeus, 1758
Hirudo medicinalis Linnaeus, 1758
Geographic distribution. Europe, Asia (
Natural hosts. Immature stages usually on amphibians. Adults on mammals. Zoonotic on humans (
Route of infection. Exposure to fresh water (
Site in human host. Skin (
Vectored pathogens. Aeromonas spp. (
Hirudo nipponia Whitman, 1886
Geographic distribution. Russia, Japan, Southeast Asia (
Natural hosts. Immature stages usually on amphibians. Adults on mammals. Zoonotic on humans (
Route of infection. Exposure to fresh water (
Site in human host. Skin, Eye (
Vectored pathogens. None.
Hirudo orientalis Utevsky & Trontelj, 2005
Geographic distribution. Central Asia, Eastern Europe (
Natural hosts. Immature stages usually on amphibians. Adults on mammals. Zoonotic on humans (
Route of infection. Exposure to fresh water (
Site in human host. Skin, Eye (
Vectored pathogens. Aeromonas spp. (
Hirudo troctina Johnson, 1816
Geographic distribution. North Africa, Iberian Peninsula (
Natural hosts. Immature stages usually on amphibians. Adults on mammals. Zoonotic on humans (
Route of infection. Exposure to fresh water (
Site in human host. Skin, Eye (
Vectored pathogens. None.
Hirudo verbena Carena, 1820
Geographic distribution. Mediterranean Europe (
Natural hosts. Immature stages usually on amphibians. Adults on mammals. Zoonotic on humans (
Route of infection. Exposure to fresh water (
Site in human host. Skin (
Vectored pathogens. Aeromonas spp. (
Genus Hirudinaria Whitman, 1886
Hirudinaria manillensis (Lesson, 1842)
Hirudo multistriata Schmarda, 1861
Hirudo luzoniae Kinberg, 1866
Hirudo maculosa Grube, 1868
Hirudo maculata Baird, 1869
Limnatis granulosa Blanchard, 1893
Hirudo boyntoni Wharton, 1913
Geographic distribution. Southeast Asia (
Natural hosts. Mammals, including buffalo, cattle. Zoonotic in humans (
Route of infection. Exposure to fresh water (
Site in human host. Upper respiratory tract (
Vectored pathogens. None
Genus Limnatis Moquin-Tandon, 1827
Limnatis nilotica (Savigny, 1822)
Geographic distribution. Southern Europe, North Africa, Middle East (
Natural hosts. Mammals, including sheep, cattle, dogs, and donkeys. Zoonotic on humans (
Route of infection. Exposure to fresh water
Site in human host. Upper respiratory tract (
Vectored pathogens. None.
Genus Poecilobdella Blanchard, 1893
Poecilobdella granulosa (Savigny, 1822)
Geographic distribution. India, Sri Lanka, Southeast Asia (
Natural hosts. Amphibians, Mammals. Zoonotic in humans (
Route of infection. Exposure to fresh water (
Site in human host. Skin, upper respiratory tract (
Vectored pathogens. None.
Poecilobdella viridis Moore in Harding & Moore, 1927
Geographic distribution. India, Sri Lanka (
Natural hosts. Amphibians, Mammals. Zoonotic in humans (
Route of infection. Exposure to fresh water (
Site in human host. Upper respiratory tract (
Vectored pathogens. None.
●●●●●●●● Macrobdellidae Richardson, 1969
Genus Macrobdella Verrill, 1872
Macrobdella decora (Say, 1824)
Geographic distribution. Eastern North America, Mexico (
Natural hosts. Various vertebrate animals. Zoonotic on humans (
Route of infection. Exposure to fresh water (
Site in human host. Skin (
Vectored pathogens. None.
Macrobdella diplotertia Meyer, 1975
Geographic distribution. East-central United States (
Natural hosts. Various vertebrate animals. Zoonotic on humans (
Route of infection. Exposure to fresh water (
Site in human host. Skin (
Vectored pathogens. None.
Macrobdella ditetra Moore, 1953
Geographic distribution. Southeastern United States (
Natural hosts. Various vertebrate animals. Zoonotic on humans(
Route of infection. Exposure to fresh water (
Site in human host. Skin (
Vectored pathogens. None.
Macrobdella mimicus Phillips, 2019
Geographic distribution. Northeastern United States (
Natural hosts. Various vertebrate animals. Zoonotic on humans (
Route of infection. Exposure to fresh water (
Site in human host. Skin (
Vectored pathogens. None.
Macrobdella sestertia Whitman, 1886
Geographic distribution. Northeastern United States (
Natural hosts. Various vertebrate animals. Zoonotic on humans (
Route of infection. Exposure to fresh water (
Site in human host. Skin (
Vectored pathogens. None.
●●●●●●●● Praeobdellidae Sawyer, 1986
Genus Dinobdella Moore in Harding & Moore, 1927
Dinobdella ferox (Blanchard, 1896)
Geographic distribution. India, Southeast Asia (
Natural hosts. Various mammals. Zoonotic on humans (
Route of infection. Exposure to fresh water (
Site in human host. Nasal mucosa (
Vectored pathogens. None.
Genus Myxobdella Oka, 1917
Myxobdella africana Moore, 1939
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Mammals, including dogs. Zoonotic in humans (
Route of infection. Exposure to fresh water (
Site in human host. Upper respiratory tract (
Vectored pathogens. None.
Genus Tyrannobdella Philipps et al., 2010
Tyrannobdella rex
Geographic distribution. Amazon South America (
Natural hosts. Unknown; presumed zoonotic on humans (
Route of infection. Exposure to fresh water (
Site in human host. Nasopharynx (
Vectored pathogens. None.
●●●●● Cestoda Rudolphi, 1809
●●●●●● Eucestoda Southwell, 1930
●●●●●●● Diphyllobothriidea
●●●●●●●● Diphyllobothriidae Lühe, 1910
Genus Adenocephalus Nybelin, 1931
Adenocephalus pacificus Nybelin, 1931
Adenocephalus septentrionalis Nybelin, 1931
Diphyllobothrium arctocephali Drummond, 1937
Diphyllobothrium krotovi Delyamure, 1955
Dibothriocephalus atlanticum Delyamure & Parukhin, 1968
Geographic distribution. Coastal Pacific waters and southern Africa (
Natural hosts. The first arthropod intermediate host is unknown, but presumed to be marine copepods. The second intermediate hosts are various marine fish. Definitive hosts are eared seals and sea lions; dogs and jackals can serve as reservoir hosts. Zoonotic in humans (
Route of infection. Ingestion of plerocercoids in infected fish (
Site in human host. Small intestine (
Genus Dibothriocephalus Lühe, 1899
Dibothriocephalus dalliae (Rausch, 1956)
Geographic distribution. Northern Pacific (Alaska and northeastern Siberia) (
Natural hosts. First intermediate hosts are freshwater copepods. Second intermediate hosts are freshwater fish, primarily Alaska blackfish (Dallia pectoralis). Definitive hosts are Arctic fox, with domestic dogs as reservoir hosts. Zoonotic in humans (
Route of infection. Ingestion of plerocercoids in infected fish (
Site in human host. Small intestine (
Dibothriocephalus dendriticus (Nitzsch, 1824)
Dibothriocephalus fissiceps Creplin, 1829
Dibothriocephalus cordiceps Leidy, 1872
Dibothriocephalus exile Linton, 1892
Sparganum sebago Ward, 1910
Dibothriocephalus minor Cholodkovsky, 1916
Diphyllobothrium canadense Cooper, 1921
Diphyllobothrium strictum Talysin, 1932
Diphyllobothrium obdoriense Piotnikoff, 1933
Diphyllobothrium laruei Vergeer, 1934
Diphyllobothrium nenzi Petrov, 1938
Diphyllobothrium oblongatum Thomas, 1946
Diphyllobothrium medium Fahmy, 1954
Diphyllobothrium microcordiceps Szidat & Soria, 1957
Diphyllobothrium norvegicum Vik, 1957
Geographic distribution. Holarctic (
Natural hosts. The first intermediate hosts are freshwater copepods. The second intermediate and paratenic hosts are many different freshwater fish. Definitive hosts are fish-eating birds, primarily gulls, and mammals, including wild and domestic canids, bears, and otters. Zoonotic in humans (
Route of infection. Ingestion of plerocercoids in infected fish (
Site in human host. Small intestine (
Dibothriocephalus hians Diesing, 1850
Geographic distribution. Mediterranean and Circumboreal (
Natural hosts. The first intermediate hosts are presumed to be marine copepods. The second intermediate hosts are unknown, but presumed to be marine fish. Definitive hosts are seals. Zoonotic in humans (
Route of infection. Ingestion of plerocercoids in infected fish (
Site in human host. Small intestine (
Dibothriocephalus latus (Linnaeus, 1758)
Diphyllobothrium americanum Hall & Wigdor, 1918
Diphyllobothrium tungussicum Podyapolskaya & Gnedina, 1932
Diphyllobothrium skrjabini Plotnikoff, 1933
Geographic distribution. Holarctic, South America (
Natural hosts. The first intermediate hosts are freshwater copepods. The second intermediate and paratenic hosts are freshwater fish, including perch, pike, burbot, walleye, and pikeperch. Definitive hosts are fish-eating carnivores, including wild and domestic dogs and cats, bears, and mustelids. Zoonotic in humans (
Route of infection. Ingestion of plerocercoids in infected fish (
Site in human host. Small intestine (
Dibothriocephalus nihonkaiensis (Yamane et al., 1886)
Diphyllobothrium giljacicum Rutkevich, 1937
Diphyllobothrium klebanovskii Muratov & Posokov, 1988
Geographic distribution. Northern Pacific (
Natural hosts. First intermediate hosts are marine copepods. Second intermediate hosts are salmonid fish. Definitive hosts are bears, wild canids, and mink. Zoonotic in humans.
Route of infection. Ingestion of plerocercoids in infected fish (
Site in human host. Small intestine (
Dibothriocephalus ursi (Rausch, 1954)
Diphyllobothrium gonodo Yamaguti, 1942
Geographic distribution. Northern North America (
Natural hosts. First intermediate hosts are marine copepods. Second intermediate hosts are salmonid fish, primarily sockeye salmon (Oncorhynchus nerka). Definitive hosts are bears. Zoonotic in humans (
Route of infection. Ingestion of plerocercoids in infected fish (
Site in human host. Small intestine (
Genus Diphyllobothrium Cobbold, 1858
Diphyllobothrium balaenopterae (Lönnberg, 1892)
Krabbea grandis Blanchard, 1894
Diplogonoporus fukuokaensis Kamo & Miyazaki, 1970
Geographic distribution. Worldwide (
Natural hosts. First intermediate hosts are marine copepods. Second intermediate hosts are marine fish, including Japanese anchovy, Japanese sardine, and skipjack tuna. Definitive hosts are baleen whales. Zoonotic in humans (
Route of infection. Ingestion of plerocercoids in infected fish (
Site in human host. Small intestine (
Diphyllobothrium stemmacephalum Cobbold, 1858
Diphyllobothrium ponticum Delyamure, 1971
Diphyllobothrium yonagoense Yamane et al., 1981
Geographic distribution. Northern Hemisphere (
Natural hosts. First intermediate hosts are presumed to be marine copepods. Second intermediate hosts are unknown, but presumed to be marine fish. Definitive hosts are dolphins and porpoises. Zoonotic in humans (
Route of infection. Ingestion of plerocercoids in infected fish (
Site in human host. Small intestine (
Diphyllobothrium , incertae sedis:
Diphyllobothrium cordatum (Leuckart, 1863)
Geographic distribution. Circumpolar (
Natural hosts. First intermediate hosts are presumed to be marine copepods. Second intermediate hosts are unknown, but presumed to be marine fish. Definitive hosts are seals and walrus. Zoonotic in humans (
Route of infection. Ingestion of plerocercoids in infected fish (
Site in human host. Small intestine (
Diphyllobothrium lanceolatum (Krabbe, 1865)
Geographic distribution. Circumpolar (
Natural hosts. First intermediate hosts are marine copepods. Second intermediate hosts are marine fish, including sardine cisco (Coregonus sardinella). Definitive hosts are seals. Zoonotic in humans (
Route of infection. Ingestion of plerocercoids in infected fish (
Site in human host. Small intestine (
Genus Spirometra Faust et al., 1929
Spirometra decepiens (Diesing, 1850)
Geographic distribution. North and South America, Southeast Asia (
Natural hosts. First intermediate hosts are believed to be freshwater copepods. Second intermediate hosts are believed to be freshwater fish and/or amphibians. Definitive hosts are wild and domestic cats; dogs may serve as reservoir hosts. Zoonotic in humans as dead-end hosts that harbor plerocercoid larvae (
Route of infection. Ingestion of plerocercoids in infected paratenic or intermediate host; ingestion of water containing copepods infected with procercoids (
Site in human host. Skin and soft tissues, pleural and peritoneal cavities, abdominal viscera, eye, CNS (
Spirometra erinaceieuropaei (Rudolphi, 1819)
Geographic distribution. Europe, Asia, and Australia (
Natural hosts. First intermediate hosts are freshwater copepods. Second intermediate hosts are amphibians, reptiles and mammals. Definitive hosts are believed to be wild and domestic canids and felids. Zoonotic in humans as dead-end hosts that harbor plerocercoid larvae (
Route of infection. Ingestion of plerocercoids in infected paratenic or intermediate host; ingestion of water containing copepods infected with procercoids (
Site in human host. Skin and soft tissues, pleural and peritoneal cavities, abdominal viscera, eye, CNS as plerocercoid larvae (spargana); rarely as adults in small intestine (
Spirometra mansoni (Joyeux & Houdemer, 1928)
Geographic distribution. Southeast Asia (
Natural hosts. First intermediate hosts are freshwater copepods. Second intermediate hosts are amphibians, while reptiles, birds, and pigs may serve as paratenic hosts. Definitive hosts are felids and canids. Zoonotic in humans as dead-end hosts that harbor plerocercoid larvae (
Route of infection. Ingestion of plerocercoids in infected paratenic or intermediate host; ingestion of water containing copepods infected with procercoids (
Site in human host. Skin and soft tissues, pleural and peritoneal cavities, abdominal viscera, eye, CNS (
Spirometra mansonoides (Mueller, 1935)
Geographic distribution. North America (
Natural hosts. First intermediate hosts are freshwater copepods. Second intermediate hosts are amphibians, reptiles, birds, small mammals. Definitive hosts are felids and canids. Zoonotic in humans as dead-end hosts that harbor plerocercoid larvae (
Route of infection. Ingestion of plerocercoids in infected paratenic or intermediate host; ingestion of water containing copepods infected with procercoids (
Site in human host. Skin and soft tissues, pleural and peritoneal cavities, abdominal viscera, eye, CNS (
Spirometra ranarum (Gastaldi, 1854)
Geographic distribution. Africa, Southeast Asia (
Natural hosts. First intermediate hosts are freshwater copepods. Second intermediate hosts are amphibians and reptiles. Definitive hosts are wild and domestic felids and canids. Zoonotic in humans as dead-end hosts that harbor plerocercoid larvae (
Route of infection. Ingestion of infected intermediate or paratenic host (
Site in human host. Skin and soft tissues, pleural and peritoneal cavities, abdominal viscera, eye, CNS (
Spirometra spp.
Geographic distribution. East Africa (
Natural hosts. Unknown (
Route of infection. Either ingestion of plerocercoids in undercooked intermediate or paratenic hosts, or water containing copepods infected with procercoids (
Site in human host. Skin and soft tissues (
Notes. Several infections with Spirometra sp. have been confirmed in South Sudan and sporadically in other East African countries. Molecular data have confirmed distinctiveness from other known zoonotic Spirometra spp., but no specific identification has been determined (
Diphyllobothriidae, incertae sedis:
Sparganum proliferum (Ilima, 1905)
Geographic distribution. Undefined (
Natural hosts. Unknown, currently known only from humans in which it is believed to be zoonotic (
Route of infection. Unknown, but presumed to be ingestion of infected intermediate or paratenic host (
Site in human host. Skin and soft tissues, pleural and peritoneal cavities, abdominal viscera, eye, CNS (
Notes. The name Sparganum proliferum is the name given to an enigmatic parasite of unknown affinities. To date, it is only known from its larval form from humans.
●●●●●●● Cyclophyllidea van Beneden in Braun, 1990
●●●●●●●● Dipylidiidae Stiles, 1896
Genus Dipylidium Leuckart, 1863
Microtaenia Sedgwick in Claus & Sedwick, 1884
Dipylidium caninum (Linnaeus, 1758)
Geographic distribution. Worldwide (
Natural hosts. Intermediate hosts are insects, primarily fleas (Ctenocephalides, Pulex) and lice (Trichodectes). Definitive hosts are wild and domestic felids and canids. Zoonotic in humans (
Route of infection. Ingestion of cysticercoids in infected arthropod intermediate host (
Site in human host. Small intestine (
●●●●●●●● Hymenolepididae Ariola, 1899
Genus Hymenolepis Weinland, 1858
Hymenolepis diminuta (Rudolphi, 1819)
Taenia flavopunctata Weinland, 1858
Geographic distribution. Worldwide (
Natural hosts. Intermediate hosts are insects, commonly granary beetles. Definitive hosts are rodents (primarily rats). Zoonotic in humans (
Route of infection. Ingestion of cysticercoids infected insect intermediate host (
Site in human host. Small intestine (
Hymenolepis hibernia Montgomery et al., 1987
Geographic distribution. Europe, Asia (
Natural hosts. Intermediate hosts are beetles. Definitive hosts are mice in the genus Apodemus. Zoonotic in humans (
Route of infection. Presumed ingestion of cysticercoids in infected insect intermediate host (
Site in human host. Small intestine (
Genus Rodentolepis Spasskii, 1954
Rodentolepis microstoma (Dujardin, 1845)
Geographic distribution. Worldwide (
Natural hosts. Intermediate hosts are insects, commonly granary beetles and fleas. Definitive hosts are fleas. Zoonotic in humans (
Route of infection. Presumably, ingestion of cysticercoids in infected insect intermediate host (
Site in human host. Small intestine (
Notes. The few cases of H. microstoma in humans have been diagnosed by molecular detection in stool (
Rodentolepis nana (Bilharz, 1851)
Hymenolepis fraterna Stiles, 1906
Geographic distribution. Worldwide (
Natural hosts. Intermediate hosts are insects, commonly granary beetles and fleas. Definitive hosts are rodents. Zoonotic in humans, although human-to-human transmission can occur (
Route of infection. Ingestion of cysticercoids in infected insect intermediate host; ingestion of eggs on fecally contaminated fomites (
Site in human host. Small intestine (
●●●●●●●● Taeniidae Ludwig, 1886
Genus Echinococcus Rudolphi, 1801
Echinococcus canadensis Webster & Cameron, 1961
Echinococcus granulosus borealis Williams & Sweatman, 1863
Echinococcus G6, camel-pig strain
Echinococcus G7, camel-pig strain
Echinococcus G8, American cervid strain
Echinococcus G10, Fennoscandian strain
Geographic distribution. North America, Europe, Middle East, China, east Africa (
Natural hosts. Intermediate hosts are camels, pigs, goats, and deer. Definitive hosts are wild and domestic canids. Zoonotic in humans as dead-end hosts harboring larval cysts (
Route of infection. Ingestion of eggs in food, water, fomites contaminated with dog feces (
Site in human host. Disseminated infection, common sites of colonization are liver, lung, brain, bone (
Echinococcus equinus Willams & Sweatman, 1963
Echinococcus G4, horse strain
Geographic distribution. Europe, North Africa, Middle East (
Natural hosts. Intermediate hosts are horses. Definitive hosts are wild and domestic canids. Zoonotic in humans as dead-end hosts harboring larval cysts (
Route of infection. Ingestion of eggs in food, water, fomites contaminated with canid feces (
Site in human host. Disseminated infection, common sites of colonization are liver, lung, brain, bone (
Echinococcus granulosus (Batsch, 1796)
Echinococcus minimus Cameron, 1926
Echinococcus longimanubrius Cameron, 1926
Echinococcus cameroni Ortlepp, 1934
Echinococcus lycaontis Ortlepp, 1934
Echinococcus intermedius Lopez-Neyra & Soler Planas, 1943
Echinococcus patagonicus Szidat, 1960
Echinococcus cepanzoi Szidat, 1971
Echinococcus G1, sheep-buffalo strain
Echinococcus G2, sheep-buffalo strain
Echinococcus G3, sheep-buffalo strain
Geographic distribution. Worldwide (
Natural hosts. Intermediate hosts are primarily sheep, goats, cattle, and buffalo. Definitive hosts are wild and domestic canids. Zoonotic in humans as dead-end hosts harboring larval cysts (
Route of infection. Ingestion of eggs in food, water, fomites contaminated with canid feces (
Site in human host. Disseminated infection, common sites of colonization are liver, lung, brain, bone (
Echinococcus multilocularis (Leuckart, 1863)
Echinococcus sibiricensis Rausch & Schiller, 1964
Echinococcus russicensis Tang et al., 2007
Geographic distribution. Europe, Asia, North America (
Natural hosts. Intermediate hosts are rodents, primarily voles. Definitive hosts are wild canids, primarily red fox (Vulpes vulpes); raccoon dogs, domestic dogs, and domestic cats may serve as reservoir hosts. Zoonotic in humans as dead-end hosts harboring larval cysts (
Route of infection. Ingestion of eggs in food, water, fomites contaminated with canid feces (
Site in human host. Liver, with dissemination to other organs, such as lung, heart, brain, bone (
Echinococcus oligarthra Diesing, 1863
Echinococcus cruzi Brumpt & Joyeux, 1924
Echinococcus pampeanus Szidat, 1967
Geographic distribution. South America (
Natural hosts. Intermediate hosts are rodents and marsupials. Definitive hosts are wild felids. Zoonotic in humans as dead-end hosts harboring larval cysts (
Route of infection. Ingestion of eggs in food, water, fomites contaminated with felid feces (
Site in human host. Liver, peritoneal and pleural cavities, with dissemination to other organs (
Echinococcus ortleppi Lopez-Neyra & Soler Planas, 1943
Echinococcus G5, cattle strain
Geographic distribution. Africa, Europe, India, South America (
Natural hosts. Intermediate hosts are primarily bovids. Definitive hosts are wild and domestic canids. Zoonotic in humans as dead-end hosts harboring larval cysts (
Route of infection. Ingestion of eggs in food, water, fomites contaminated with canid feces (
Site in human host. Disseminated infection, common sites of colonization are liver, lung, brain, bone (
Echinococcus vogeli Rausch & Berstein, 1972
Geographic distribution. South America (
Natural hosts. Intermediate hosts are rodents, primarily paca (Cuniculus paca). Definitive hosts are bush dogs (Speothos venaticus). Zoonotic in humans as dead-end hosts harboring larval cysts (
Route of infection. Ingestion of eggs in food, water, fomites contaminated with bush dog feces (
Site in human host. Liver, peritoneal and pleural cavities, with dissemination to other organs (
Genus Hydatigera Lamarck, 1816
Hydatigera taeniaeformis (Batsch, 1786)
Cysticercus fasciolaris Rudolphi, 1808
Geographic distribution. Worldwide (
Natural hosts. Intermediate hosts are primarily rodents and lagomorphs. Definitive hosts are felids. Zoonotic in humans (
Route of infection. Unknown
Site in human host. Small intestine, liver (
Genus Taenia Linnaeus, 1758
Taenia brauni Setti, 1897
Geographic distribution. Africa (
Natural hosts. Intermediate hosts are rodents and non-human primates. Definitive hosts are canids and genets. Zoonotic in humans as dead-end hosts harboring larval cysts (
Route of infection. Ingestion of eggs in food, water, fomites contaminated with canid feces (
Site in human host. Skin and soft tissues, eyes (
Notes. Taenia brauni is often considered a subspecies or synonym of T. serialis.
Taenia crassiceps (Zeder, 1800)
Taenia hyperborea von Linstow, 1905
Geographic distribution. Northern Hemisphere (
Natural hosts. Intermediate hosts are rodents. Definitive hosts are canids, primarily foxes Zoonotic in humans as dead-end hosts harboring larval cysts (
Route of infection. Ingestion of eggs in food, water, fomites contaminated with canid feces (
Site in human host. Skin and soft tissues, eyes, CNS (
Taenia glomeratus (Railliett & Henry, 1915)
Geographic distribution. Africa (
Natural hosts. Intermediate hosts are rodents. Definitive hosts are canids and genets. Zoonotic in humans as dead-end hosts harboring larval cysts (
Route of infection. Ingestion of eggs in food, water, fomites contaminated with canid feces (
Site in human host. Eyes (
Notes. Taenia glomeratus is often considered a subspecies or synonym of T. serialis.
Taenia martis (Zeder, 1803)
Geographic distribution. North America, Europe (
Natural hosts. Intermediate hosts include rodents. Definitive hosts are mustelids and foxes. Zoonotic in humans has a dead-end host harboring larval cysts (
Route of infection. Ingestion of eggs in food, water, fomites contaminated with feces of definitive host (
Site in human host. Skin and soft tissues, CNS, eyes (
Taenia multiceps Leske, 1790
Geographic distribution. Worldwide (
Natural hosts. Intermediate hosts are ungulates, primarily sheep. Definitive hosts are canids, primarily foxes. Zoonotic in humans as dead-end hosts harboring larval cysts (
Route of infection. Ingestion of eggs in food, water, fomites contaminated with canid feces (
Site in human host. Skin and soft tissues, CNS (
Taenia saginata Goeze, 1782
Taenia confusa Ward, 1896
Taenia africana von Linstow, 1900
Taenia hominis von Linstow, 1904
Geographic distribution. Worldwide (
Natural hosts. Intermediate hosts are cattle. Definitive hosts are humans (
Route of infection. Ingestion of cysticercoids in infected cattle (
Site in human host. Small intestine (
Taenia serialis Gervais, 1847
Multiceps radians Joyeux et al., 1922
Geographic distribution. Worldwide; highest prevalence in Africa (
Natural hosts. Intermediate hosts include rabbits, rodents, cattle, sheep, goats. Definitive hosts are wild and domestic canids. Zoonotic in humans as dead-end hosts harboring larval cysts (
Route of infection. Ingestion of eggs in food, water, fomites contaminated with canid feces (
Site in human host. CNS (
Taenia solium Linnaeus, 1758
Cysticercus cellulosae Gmelin, 1790
Geographic distribution. Worldwide (
Natural hosts. Intermediate hosts are pigs. Definitive hosts are humans, although in cases of cysticercosis humans function as dead-end intermediate hosts (
Route of infection. Ingestion of cysticercoids in infected pigs (taeniasis); ingestion of eggs in food, water, fomites contaminated with human feces (cysticercosis) (
Site in human host. Small intestine (taeniasis); disseminated infection with predilection for CNS (cysticercosis) (
Taenia suihominis
Taenia asiatica Eom & Rim, 1993
Taenia saginata asiatica Eom & Rim, 1993
Taenia asiaticus Eom et al., 2020
Geographic distribution. East Asia (
Natural hosts. Intermediate hosts are pigs. Definitive hosts are humans (
Route of infection. Ingestion of cysticerci in infected pigs (
Site in human host. Small intestine (
Genus Versteria
Geographic distribution. Europe, Central Asia, North America (
Natural hosts. Intermediate hosts are rodents; non-human primates can be incidental hosts. Definitive hosts are mustelids. Zoonotic in humans (
Route of infection. Presumably by the ingestion of eggs in food, water, fomites contaminated with feces of definitive host (
Site in human hose. Various organs, disseminated infection (
Notes. Human and primate Versteria infections have not been identified to species level but bear close genetic resemblance to isolates from North American mink and are somewhat similar to isolates of V. mustelae (Gmelin, 1790) from European mink (
●●●●●●●● Anoplocephalidae Cholodkovsky, 1902
Genus Bertiella Stiles & Hassall, 1902
Bertia Blanchard, 1891
Bertiella mucronotata (Meyner, 1895)
Geographic distribution. South America, Caribbean (
Natural hosts. First intermediate hosts are oribatid mites. Definitive hosts are New World monkeys. Zoonotic in humans (
Route of infection. Ingestion of cysticercoids in infected mite intermediate host (
Site in human host. Small intestine (
Bertiella studeri (Blanchard, 1891)
Geographic distribution. Africa, Asia (
Natural hosts. First intermediate hosts are oribatid mites. Definitive hosts are Old World monkeys and non-human apes. Zoonotic in humans (
Route of infection. Ingestion of cysticercoids in infected mite intermediate host (
Site in human host. Small intestine (
Genus Inermicapsifer Janicki, 1910
Inermicapsifer madagascariensis (Davaine, 1870)
Acanthocephala arvicanthidis Kofend, 1917
Raillietina cubensis Kouri, 1938
Geographic distribution. Sub-Saharan Africa, South America, West Indies, Southeast Asia (
Natural hosts. Intermediate hosts are not known, but presumed to be terrestrial arthropods. Definitive hosts are rodents and hyraxes. Zoonotic in humans (
Route of infection. Ingestion of cysticercoids in infected arthropod intermediate host (
Site in human host. Small intestine (
Genus Mathevotaenia Akhumyan, 1946
Mathevotaenia symmetrica (Baylis, 1927)
Geographic distribution. Europe, Asia (
Natural hosts. Intermediate hosts are suspected as being arthropods. Definitive hosts are rodents. Zoonotic in humans (
Route of infection. Presumably, ingestion of cysticercoids in infected arthropod intermediate host (
Site in human host. Small intestine (
Genus Moniezia Blanchard, 1891
Moniezia expansa (Rudolphi, 1810)
Geographic distribution. Worldwide (single human case from Egypt) (
Natural hosts. Intermediate hosts are mites. Definitive hosts are sheep, goats, cattle. Zoonotic in humans (
Route of infection. Presumably, ingestion of cysticercoids in infected arthropod intermediate host (
Site in human host. Small intestine (
●●●●●●●● Davaineidae Braun, 1900
Genus Raillietina Fuhrman, 1920
Raillietina celebensis (Janicki, 1902)
Taenia asiatica von Linstow, 1891
Taenia formosana Akashi, 1916
Raillietina funerebris Meggitt & Subramanian, 1927
Raillietina garrisoni Tubangui, 1931
Raillietina sinensis Hsu, 1935
Raillietina murium Joyeux & Baer, 1938
Geographic distribution. Asia, Australia (
Natural hosts. Intermediate hosts are invertebrates, including insects (primarily ants and beetles) and terrestrial mollusks. Definitive hosts are rodents and shrews. Zoonotic in humans (
Route of infection. Ingestion of cysticercoids in infected arthropod intermediate host (
Site in human host. Small intestine (
Raillietina demerariensis (Daniels, 1895)
Raillietina quitensis Leon, 1935
Raillietina brumpti Doilfus, 1939
Raillietina equatoriensis Dollfus, 1939
Raillietina leoni Dollfus, 1939
Raillietina luisaleoni Dollfus, 1939
Raillietina halli Perez-Vigueras, 1934
Geographic distribution. South America, Caribbean (
Natural hosts. Intermediate hosts are invertebrates, including insects (primarily ants and beetles) and terrestrial mollusks. Definitive hosts are rodents; non-human primates may serve as reservoir hosts. Zoonotic in humans (
Route of infection. Ingestion of cysticercoids in infected arthropod intermediate host (
Site in human host. Small intestine (
Raillietina siriraji Chandler & Pradatsundarasar, 1957
Geographic distribution. Thailand (
Natural hosts. Intermediate hosts are invertebrates, including insects (primarily ants and beetles). Definitive hosts are rodents. Zoonotic in humans (
Route of infection. Ingestion of cysticercoids in infected arthropod intermediate host (
Site in human host. Small intestine (
●●●●●●●● Mesocestoididae Fuhrmann, 1907
Genus Mesocestoides Valliant, 1863
Mesocestoides lineatus (Goeze, 1782)
Geographic distribution. Europe and Asia (
Natural hosts. The complete life cycle and presumed number of hosts is not completely understood. The presumed first intermediate host is believed to be an arthropod. The second intermediate hosts are a variety of vertebrates, including small mammals, birds, reptiles, and amphibians. Definitive hosts are carnivores, including foxes, wolves, raccoon dogs, and European badgers. Zoonotic in humans (
Route of infection. Unknown; presumed to be ingestion of tetrathyridia in meat and viscera of infected second intermediate hosts (
Site in human host. Small intestine (
Mesocestoides variabilis Mueller, 1928
Geographic distribution. North America (
Natural hosts. The complete life cycle and presumed number of hosts is not completely understood. The presumed first intermediate host is believed to be an arthropod. The second intermediate hosts are a variety of vertebrates, including small mammals, birds, reptiles, and amphibians. Definitive hosts include wild and domestic canids and felids, mustelids, and opossums. Zoonotic in humans (
Route of infection. Unknown; presumed to be ingestion of tetrathyridia in meat and viscera of infected second intermediate hosts (
Site in human host. Small intestine (
●●●●● Trematoda Rudolphi, 1808
●●●●●● Digenea Carus, 1863
●●●●●●● Diplostomida Olson et al., 2003
●●●●●●●● Diplostomata Olson et al., 2003
●●●●●●●●● Brachylaeimidae Joyeux & Foley, 1930
Genus Brachylaeima Dujardin, 1843
Brachylaeima cribbi Butcher & Grove, 2001
Geographic distribution. Australia (
Natural hosts.
First intermediate hosts are terrestrial snails in the genus Theba. Second intermediate hosts are land snails in the genus Cernualla. Definitive hosts include a variety of birds, mammals, and reptiles. Zoonotic in humans (
Route of infection.
Ingestion of metacercariae in infected snail intermediate hosts (
Site in human host.
Small intestine (
●●●●●●●●● Cyathocotylidae Mühling, 1898
Genus Prohemistomum Odhner, 1913
Prohemistomum vivax (Sonsino, 1892)
Geographic distribution. Europe, North Africa, Middle East (
Natural hosts. First intermediate hosts are freshwater snails in the genus Cleopatra. Second intermediate hosts are various brackish water and freshwater fish. Definitive hosts are felids, canids, and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish intermediate hosts (
Site in human host. Small intestine (
●●●●●●●●● Diplostomidae Poirier, 1886
Genus Alaria Schrank, 1788
Alaria americana Hall & Wigdor, 1918
Geographic distribution. North America (
Natural hosts. First intermediate hosts are snails in the genera Planorbis, Heliosoma, Lymnea, and Anisus. Second intermediate hosts are amphibians; many vertebrate animals can serve as paratenic hosts. Definitive hosts are carnivores. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in undercooked game meat (
Site in human host. Subcutaneous tissues, eyes, lungs, disseminated infections (
Genus Fibricola Dubois, 1932
Fibricola cratera (Barker & Noll, 1915)
Geographic distribution. North America (
Natural hosts. First intermediate hosts are freshwater snails in the genus Physa. Second intermediate hosts are amphibians. Definitive hosts are rodents and shrews. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected amphibian intermediate hosts (
Site in human host. Small intestine (
Genus Neodiplostomum Railliet, 1919
Neodiplostomum seoulense Seo et al., 1964
Geographic distribution. China, South Korea (
Natural hosts. First intermediate hosts are freshwater snails in the genera Hippeutis and Segmentina. Second intermediate hosts are amphibians; snakes can serve as paratenic hosts. Definitive hosts are rodents and humans (
Route of infection. Ingestion of metacercariae in infected reptile and amphibian intermediate and paratenic hosts (
Site in human host. Small intestine (
●●●●●●●●● Strigeidae Railliet, 1919
Genus Cotylurus Szidat, 1928
Cotylurus japonicus Ishii, 1932
Geographic distribution. Central and Southeast Asia, Russia, Japan (
Natural hosts. First intermediate hosts are unknown but hypothesized to be freshwater snails. Second intermediate hosts are unknown but presumed to be freshwater snails. Definitive hosts are ducks. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected insect intermediate hosts (
Site in human host. Small intestine (
●●●●●●●●● Schistosomatidae Stiles & Hassall, 1898
Genus Schistosoma Weinland, 1858
Schistosoma bovis (Bilharz, 1852)
Geographic distribution. Southern Europe, Middle East, South Asia, Africa (
Natural hosts. First intermediate hosts are snails in the genus Bulinus. Definitive hosts are ruminants, primarily cattle. Zoonotic in humans (
Route of infection. Penetration of skin by free-swimming cercariae
Site in human host. Mesenteric veins of the large intestine (
Notes. Human infections with hybrids of S. bovis and S. haematobium have been confirmed using molecular methods (
Schistosoma guineensis Pagès et al., 2003
Schistosoma intercalatum, Guinea strain
Geographic distribution. West Africa (
Natural hosts. First intermediate hosts are snails in the genus Bulinus. Definitive hosts are humans, rodents, ruminants (
Route of infection. Penetration of skin by free-swimming cercariae (
Site in human host. Mesenteric veins of the large intestine (
Schistosoma haematobium (Bilharz, 1852)
Geographic distribution. Africa, isolated regions of the Middle East (
Natural hosts. First intermediate hosts are snails in the genus Bulinus. Definitive hosts are humans (
Route of infection. Penetration of skin by free-swimming cercariae (
Site in human host. Venous plexus of the urinary bladder (
Notes. Human infection of hybrids of S. haematobium and S. bovis have been documented in Corsica, France (
Schistosoma intercalatum Fisher, 1934
Geographic distribution. Democratic Republic of the Congo (
Natural hosts. First intermediate hosts are snails in the genus Bulinus. Definitive hosts are humans, rodents, ruminants (
Route of infection. Penetration of skin by free-swimming cercariae (
Site in human host. Mesenteric veins of the large intestine (
Schistosoma japonicum (Katsurada, 1904)
Geographic distribution. China, Philippines, Indonesia (Sulawesi) (
Natural hosts. First intermediate hosts are snails in the genus Oncomelania. Definitive hosts include a variety of mammals, including canids, felids, pigs, ruminants, rodents, and humans (
Route of infection. Penetration of skin by free-swimming cercariae (
Site in human host. Mesenteric veins of the small and large intestine (
Schistosoma mansoni Sambon, 1907
Geographic distribution. Sub-Saharan Africa, South America, Caribbean, parts of the Arabian Peninsula (
Natural hosts. First intermediate hosts are snails in the genus Biomphalaria. Definitive hosts are humans, occasionally non-human primates (
Route of infection. Penetration of skin by free-swimming cercariae (
Site in human host. Mesenteric veins of the large intestine (
Schistosoma mattheei Veglia & LeRoux, 1929
Geographic distribution. Africa, Middle East (
Natural hosts. First intermediate hosts are snails in the genus Bulinus. Definitive hosts are wild and domestic ruminants. Zoonotic in humans (
Route of infection. Penetration of skin by free-swimming cercariae (
Site in human host. Presumed to be venous plexus of the urinary bladder (
Notes. Reports of patent, egg-producing human infections with S. mattheei are most likely a result of hybridization of this species with S. haematobium. Dead-end acute infections with S. mattheei × S. haematobium have been confirmed using molecular methods (
Schistosoma mekongi Voge et al., 1978
Geographic distribution. Mekong River Valley of Cambodia and Laos (
Natural hosts. First intermediate host is the snail Neotricula aperta. Definitive hosts include a variety of mammals, including canids, felids, pigs, ruminants, rodents, and humans (
Route of infection. Penetration of skin by free-swimming cercariae (
Site in human host. Mesenteric veins of the large intestine (
Cercarial dermatitis
Many species of avian, and some mammalian, schistosomes cause a limited cutaneous reaction in humans referred to as cercarial dermatitis (or “swimmer’s itch”). The identity of causative agents is typically inferred via environmental investigations following outbreaks and may or may not be identified to species level; only the major genera are listed here:
Genus Anserobilharzia Brandt et al., 2013
Geographic distribution. Northern Hemisphere (
Natural hosts. Intermediate hosts are freshwater snails in the family Planorbidae. Definitive hosts are charadriiform birds. Zoonotic in humans (
Route of infection. Penetration of skin by free-swimming cercariae (
Site in human host. Skin (
Genus Austrobilharzia Johnston, 1917
Geographic distribution. Northern Hemisphere, Australia (
Natural hosts. Intermediate hosts are freshwater snails in the family Planorbidae. Definitive hosts are charadriiform birds. Zoonotic in humans (
Route of infection. Penetration of skin by free-swimming cercariae (
Site in human host. Skin (
Genus Bilharziella Looss, 1899
Geographic distribution. Europe (
Natural hosts. Intermediate hosts are freshwater snails in the family Planorbidae. Definitive hosts are waterfowl and other wading birds. Zoonotic in humans (
Route of infection. Penetration of skin by free-swimming cercariae (
Site in human host. Skin (
Genus Bivitellobilharzia Vogel & Minning, 1940
Geographic distribution. Africa, Asia (
Natural hosts. Snail intermediate hosts are unknown. Definitive hosts are elephants and rhinoceroses. Zoonotic in humans (
Route of infection. Penetration of skin by free-swimming cercariae (
Site in human host. Skin (
Genus Gigantobilharzia Odhner, 1910
Geographic distribution. North America (
Natural hosts. Intermediate hosts are freshwater snails in the family Physidae. Definitive hosts are passerine birds. Zoonotic in humans (
Route of infection. Penetration of skin by free-swimming cercariae (
Site in human host. Skin (
Genus Heterobilharzia Price, 1929
Geographic distribution. North America (
Natural hosts. Intermediate hosts are freshwater snails in the family Lymnaeidae. Definitive hosts are various mammals, including carnivores and marsupials. Zoonotic in humans (
Route of infection. Penetration of skin by free-swimming cercariae (
Site in human host. Skin (
Genus Ornithobilharzia Odhner, 1912
Geographic distribution. Worldwide (
Natural hosts. Intermediate hosts are marine snails in the family Batillaridae. Definitive hosts are various birds and mammals. Zoonotic in humans (
Route of infection. Penetration of skin by free-swimming cercariae (
Site in human host. Skin (
Genus Trichobilharzia Skrjabin & Zakharow, 1920
Geographic distribution. Worldwide (
Natural hosts. Intermediate hosts are freshwater snails in the families Lymnaeidae and Physidae. Definitive hosts are waterfowl. Zoonotic in humans (
Route of infection. Penetration of skin by free-swimming cercariae (
Site in human host. Skin (
●●●●●●● Plagiorchiida La Rue, 1957
●●●●●●●● Bucephalata La Rue, 1926
●●●●●●●●● Gymnophallidae Odhner, 1905
Genus Gymnophalloides Fujita, 1925
Gymnophalloides seoi Chai et al., 2003
Geographic distribution. South Korea (
Natural hosts. First intermediate hosts are unknown. Second intermediate hosts are oysters in the genus Crassostrea. Definitive hosts are oystercatchers (Haematopus). Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected oyster intermediate hosts (
Site in human host. Small intestine (
●●●●●●●● Echinostomata La Rue, 1926
●●●●●●●●● Himasthlidae Odhner, 1910
Genus Acanthoparyphium Dietz, 1909
Acanthoparyphium tyosenense Yamaguti, 1939
Geographic distribution. Korea, Japan (
Natural hosts. First intermediate hosts are marine gastropods. The second intermediate hosts are brackish water bivalves. Definitive hosts are ducks. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected bivalves (
Site in human host. Small intestine (
Genus Himasthla Dietz, 1909
Himasthla muehlensi Vogel, 1933
Geographic distribution. North America, Colombia (
Natural hosts. First intermediate hosts are unknown, presumed to be marine gastropods. Second intermediate hosts are presumed to be marine clams and mussels. Definitive hosts are birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected mollusk intermediate hosts (
Site in human host. Small intestine (
●●●●●●●●● Echinochasmidae Odhner, 1910
Genus Echinochasmus Dietz, 1909
Echinochasmus caninus (Verma, 1935)
Geographic distribution. Southeast Asia, India (
Natural hosts. First intermediate hosts are unknown. Second intermediate hosts are freshwater fish in the genus Macropodus. Definitive hosts are wild and domestic canids. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish intermediate host (
Site in human host. Small intestine (
Echinochasmus fujianensis Chen, in Chen et al., 1992
Geographic distribution. China (
Natural hosts. First intermediate hosts are freshwater snails in the genus Bellamya Second intermediate hosts are freshwater fish in the genera Pseudorasbora and Cyprinus. Definitive hosts are wild and domestic canids and felids, pigs, and rodents. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish intermediate host (
Site in human host. Small intestine (
Echinochastmus japonicus Tanabe, 1926
Geographic distribution. Southeast Asia, Japan (
Natural hosts. First intermediate hosts are freshwater snails, including the genus Parafossarulis. Second intermediate hosts are various freshwater fish. Definitive hosts are felids, insectivores, and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish intermediate host (
Site in human host. Small intestine (
Echinochasmus jiufoensis Liang & Ke, 1988
Geographic distribution. China (
Natural hosts. First intermediate hosts are unknown. Second intermediate hosts are presumed to be freshwater fish or mollusks. Definitive hosts are felids, canids, and pigs. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate host (
Site in human host. Small intestine (
Echinochasmus liliputanus (Looss, 1896)
Geographic distribution. China, Middle East, North Africa (
Natural hosts. First intermediate hosts are freshwater snails in the genus Parafossarulus. Second intermediate hosts are freshwater fish in the genera Pseudorasbora and Carassius. Definitive hosts are felids, canids, raccoons, and badgers. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate fish host or water contaminated with metacercariae (
Site in human host. Small intestine (
Echinochasmus perfoliatus (Ratz, 1908)
Geographic distribution. Southeast Asia, Russia, Europe, North Africa (
Natural hosts. First intermediate hosts are various freshwater snails (Parafossarulus, Bithynia, Lymnaea). Second intermediate hosts are various freshwater fish (Zacco, Carassius, Pseudorasbora). Definitive hosts are felids, canids, pigs, and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish intermediate host (
Site in human host. Small intestine (
●●●●●●●●● Echinostomatidae Looss, 1899
Genus Artyfechinostomum Lane, 1915
Artyfechinostomum malayanum (Leiper, 1911)
Geographic distribution. Southeast Asia (
Natural hosts. First intermediate hosts are freshwater snails in the genera Indoplanorbis and Gyraulus. Second intermediate hosts are several freshwater snails. Definitive hosts include pigs, rodents, shrews, felids, canids. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected snail intermediate hosts (
Site in human host. Small intestine (
Artyfechinostomum oraoni Bandyopadhyay et al., 1989
Geographic distribution. India (
Natural hosts. First intermediate hosts are snails in the genus Lymnaea. Second intermediate hosts and definitive hosts are unknown; presumed zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate hosts (
Site in human host. Small intestine (
Artyfechinostomum sufratyfex Lane, 1915
Cercaria mehrai Faruqui, 1930
Geographic distribution. India, Vietnam (
Natural hosts. First intermediate hosts are snails in the genera Indoplanorbis and Lymnaea. Second intermediate hosts include freshwater snails, fish, and amphibians. Definitive hosts are pigs, canids, and rodents. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate hosts (
Site in human host. Small intestine (
Genus Echinoparyphium Dietz, 1909
Echinoparyphium recurvatum (von Linstow, 1873)
Geographic distribution. North America, Europe, North Africa, Middle East, Central and Southeast Asia (
Natural hosts. First intermediate hosts are snails in the genera Physa and Lymnaea. Second intermediate hosts include freshwater snails and amphibians. Definitive hosts are canids and rodents. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate hosts (
Site in human host. Small intestine (
Genus Echinostoma Rudolphi, 1809
Echinostoma aegyptica Khalil & Abaza, 1924
Geographic distribution. North Africa, Middle East, Southeast Asia, Japan (
Natural hosts. First and second intermediate hosts are unknown. Definitive hosts are rats. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate hosts (
Site in human host. Small intestine (
Echinostoma angustitestes Wang, 1977
Geographic distribution. China (
Natural hosts. First intermediate hosts are presumed to be freshwater snails. Second intermediate hosts are freshwater fish. Definitive hosts are dogs and livestock. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish intermediate hosts (
Site in human host. Small intestine (
Echinostoma cinetorchis Ando & Ozaki, 1923
Geographic distribution. Southeast Asia, Japan (
Natural hosts. First intermediate hosts are snails in the genera Hippeutis and Segmentina. Second intermediate hosts include freshwater snails, fish (Misgurnus), and amphibians. Definitive hosts are rats. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate hosts (
Site in human host. Small intestine (
Echinostoma ilocanum (Garrison, 1908)
Geographic distribution. Central and Southeast Asia (
Natural hosts. First intermediate hosts are snails in the genera Gyraulus and Hippeutis. Second intermediate hosts include freshwater snails in the genera Pila and Vivaparus. Definitive hosts are rats and canids. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected snail intermediate hosts(
Site in human host. Small intestine (
Echinostoma lindoense Sandground & Bonne, 1940
Geographic distribution. Europe, Southeast Asia, South America (
Natural hosts. First intermediate hosts are several genera of freshwater snails. Second intermediate hosts include freshwater snails and mussels. Definitive hosts include a variety of mammals and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected mollusk intermediate hosts (
Site in human host. Small intestine (
Echinostoma macrorchis Ando & Ozaki, 1923
Geographic distribution. Southeast Asia, Japan (
Natural hosts. First intermediate hosts are snails in the genera Segmentina and Gyraulus. Second intermediate hosts include freshwater snails (Segmentina) and amphibians. Definitive hosts are rodents and wading birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate hosts (
Site in human host. Small intestine(
Echinostoma paraensei Lie & Basch, 1967
Geographic distribution. Australia, Brazil (
Natural hosts. First and second intermediate hosts are snails in the genus Biomphalaria. Definitive hosts are rats. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected snail intermediate hosts (
Site in human host. Small intestine (
Echinostoma revolutum (Froelich, 1802)
Geographic distribution. Europe, Russia, Middle East, Central and Southeast Asia, North America (
Natural hosts. First intermediate hosts include several genera of freshwater snails. Second intermediate hosts include freshwater snails and clams, and amphibians. Definitive hosts are felids, canids, rodents, and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate hosts (
Site in human host. Small intestine (
Notes. Numerous nominal species are considered part of the “E. revolutum complex” or the “37-collar-spined Echinostoma complex”; taxonomic resolution of species within this group is an area of ongoing investigation.
Genus Hypoderaeum Dietz, 1909
Hypoderaeum conoideum (Bloch, 1782)
Geographic distribution. Southeast Asia, Japan, Europe, North and Central America (
Natural hosts. First intermediate hosts include several genera of freshwater snails. Second intermediate hosts include freshwater snails and amphibians. Definitive hosts are birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae infected intermediate hosts (
Site in human host. Small intestine (
Genus Isthmiophora Lühe, 1909
Isthmiophora hortensis (Asada, 1926)
Geographic distribution. China, Japan, Korea (
Natural hosts. First intermediate hosts include freshwater snails in the genera Lymnaea and Radix. Second intermediate hosts include several genera of freshwater fish. Definitive hosts are felids, canids, and rodents. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish intermediate hosts (
Site in human host. Small intestine (
Isthmiophora melis (Schrank, 1788)
Geographic distribution. Europe, USA, Taiwan (
Natural hosts. First intermediate hosts freshwater snails in the genus Lymnaea. Second intermediate hosts are freshwater fish and amphibians. Definitive hosts are canids, mustelids, hedgehogs, and rodents. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate hosts (
Site in human host. Small intestine (
●●●●●●●●● Fasciolidae Railliet, 1895
Genus Fasciola Linnaeus, 1758
Fasciola gigantica Cobbold, 1855
Geographic distribution. Africa, Middle East, Southeast Asia, Japan (Tolan 2011;
Natural hosts. First intermediate hosts are freshwater snails in the genus Lymnaea. Second intermediate hosts are aquatic plants. Definitive hosts are primarily sheep, also cattle, buffalo, goats, pigs. Zoonotic in humans (olan 2011;
Route of infection. Ingestion of metacercariae on contaminated aquatic vegetation (olan 2011;
Site in human host. Biliary ducts; ectopic migration to skin, brain (olan 2011;
Fasciola hepatica Linnaeus, 1758
Geographic distribution. Worldwide; hot spots of endemicity for human infection include the Bolivian Altiplano, Ecuador, Peru, Cuba, Portugal, Spain, Turkey, North Africa (Nile Delta), Iran, Vietnam (Tolan 2011).
Natural hosts. First intermediate hosts are freshwater snails, particularly members of the genera Galba, Fossaria, and Pseudosuccinea. Second intermediate hosts are aquatic plants. Definitive hosts include primarily cattle and buffalo, also sheep, goats, and deer. Zoonotic in humans (Tolan 2011).
Route of infection. Ingestion of metacercariae on contaminated aquatic vegetation (Tolan 2011).
Site in human host. Biliary ducts; ectopic migration to skin, brain (Tolan 2011).
Genus Fasciolopsis Looss, 1899
Fasciolopsis buski (Lankester in Küchenmeister, 1857)
Distoma rathouisi Poirier, 1887
Fasciolopsis fuelleborni Rodenwadt, 1909
Fasciolopsis goddardi Ward, 1910
Geographic distribution. Central and Southeast Asia (
Natural hosts. First intermediate hosts are several genera of freshwater snails, especially the genera Segmentina, Hippeutis, and Gyraulus. Second intermediate hosts are freshwater plants. Definitive hosts are pigs, rabbits, and canids. Zoonotic in humans (
Route of infection. Ingestion of metacercariae on contaminated freshwater vegetation (
Site in human host. Small intestine (
●●●●●●●●● Philophthalmidae Looss, 1899
Genus Philophthalmus Looss, 1899
Philophthalmus gralli Matthis & Leger, 1910
Philophthalmus anatinus Sugimoto, 1928
Philophthalmus nyrocae Yamaguti, 1934
Geographic distribution. East and Southeast Asia, North America, South America (
Natural hosts. Intermediate hosts are snails in the genus Melanoides. Definitive hosts are birds, primarily water birds and fowl. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in water or on submerged substrates (e.g., mollusk shells, plants); also direct exposure of eyes to free-swimming cercariae in water (
Site in human host. Eyes (
Philophthalmus palpebrarum Looss, 1899
Geographic distribution. Middle East, North Africa (
Natural hosts. Intermediate hosts are snails in the genus Melanoides. Definitive hosts are birds, primarily water birds and fowl. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in water or on submerged substrates (e.g., mollusk shells, plants); also direct exposure of eyes to free-swimming cercariae in water (
Site in human host. Eyes (
Philophthalmus lacrymosus Braun, 1902
Geographic distribution. Central and South America (
Natural hosts. Intermediate hosts are snails in the genus Melanoides. Definitive hosts are birds, primarily water birds and fowl. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in water or on submerged substrates (e.g., mollusk shells, plants); also direct exposure of eyes to free-swimming cercariae in water (
Site in human host. Eyes (
●●●●●●●● Hemiurata Skrjabin & Guschanskaja, 1954
●●●●●●●●● Isoparorchiidae Travassos, 1922
Genus Isoparorchis Southwell, 1913
Leptolecithum Kobayashi, 1915
Isoparorchis hypselobagri (Billet, 1898)
Geographic distribution. Central and Southeast Asia, Russia, Australia (
Natural hosts. First intermediate hosts are freshwater snails in the genus Melanoides. Second intermediate hosts are catfish. Definitive hosts are predator fish. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish intermediate hosts (
Site in human host. Small intestine (
●●●●●●●● Opisthorchiata La Rue, 1957
●●●●●●●●● Heterophyidae Leiper, 1909
Genus Acanthotrema Travassos, 1928
Acanthotrema felis Sohn et al., 2003
Geographic distribution. Korea (
Natural hosts. First intermediate hosts are unknown. Second intermediate hosts are brackish water fish in the genus Acanthogobius. Definitive hosts are felids. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish intermediate host (
Site in human host. Small intestine (
Genus Apophallus Lühe, 1909
Apophallus donicus (Skrjabin & Lindtrop, 1919)
Geographic distribution. North America (
Natural hosts. First intermediate hosts are freshwater snails in the genus Flumenicola. Second intermediate hosts are various freshwater fish. Definitive hosts are carnivores and lagomorphs. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish intermediate host (
Site in human host. Small intestine (
Genus Ascocotyle Looss, 1899
Ascocotyle longa Ransom, 1920
Geographic distribution. North America, Europe (
Natural hosts. First intermediate hosts are brackish water snails in the genus Helecobia. Second intermediate hosts are brackish water fish in the genus Mugil. Definitive hosts are canids. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Genus Centrocestus Looss, 1899
Centrocestus armatus (Tanabe, 1922)
Geographic distribution. Korea, Japan (
Natural hosts. First intermediate hosts are freshwater snails in the genus Semisulcospira. Second intermediate hosts are freshwater fish in the genus Zacco. Definitive hosts are wild and domestic canids and felids, rabbits, rats, and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Centrocestus cuspidatus (Looss, 1896)
Geographic distribution. Southeast Asia, North Africa, Middle East (
Natural hosts. First intermediate hosts are freshwater snails in the genus Oncomelania. Second intermediate hosts are freshwater fish in the genus Gambusia. Definitive hosts are carnivores, rodents, and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Centrocestus formosanus Nishigori, 1924
Centrocestus caninus Leiper, 1913
Geographic distribution. Southeast Asia, Central and South America, North Africa, Middle East (
Natural hosts. First intermediate hosts are freshwater snails in the genus Stenomelania. Second intermediate hosts are freshwater fish, including Cyclocheilichthys and Puntius. Definitive hosts are wild and domestic canids, chickens, and ducks. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Centrocestus kurokawai (Kurowawa, 1935)
Geographic distribution. Japan (
Natural hosts. First intermediate hosts are unknown. Second intermediate hosts are unknown but presumed to be freshwater fish. Definitive hosts unknown; presumed zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate host (
Site in human host. Small intestine (
Genus Cryptocotyle Lühe, 1899
Cryptocotyle lingua (Creplin, 1825)
Geographic distribution. North America, Europe, Russia, Japan (
Natural hosts. First intermediate hosts are brackish water snails in the genus Littorina. Second intermediate hosts are brackish and freshwater fish in the genus Gobius. Definitive hosts are carnivores, rodents, and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Genus Haplorchis Looss, 1899
Haplorchis pumilio (Looss, 1896)
Geographic distribution. Central and Southeast Asia, Australia, Middle East, North Africa, Central and South America (
Natural hosts. First intermediate hosts are snails in the genus Melania. Second intermediate hosts are various freshwater fish. Definitive hosts are carnivores. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected freshwater fish (
Site in human host. Small intestine (
Haplorchis taichui (Nishigori, 1924)
Monorchotrema microrchia Katsuta, 1932
Geographic distribution. Central and Southeast Asia, Hawaii, Middle East (
Natural hosts. First intermediate hosts are freshwater snails in the genera Melania and Melanoides. Second intermediate hosts are various freshwater fish. Definitive hosts are carnivores and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected freshwater fish (
Site in human host. Small intestine (
Haplorchis vanissimus Africa, 1938
Geographic distribution. Australia, Philippines (
Natural hosts. First intermediate hosts are unknown. Second intermediate hosts are unknown but presumed to be freshwater fish. Definitive hosts are wild and domestic canids and felids and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Haplorchis yokogawai (Katsuta, 1932)
Geographic distribution. Central and Southeast Asia, Australia, Middle East, North Africa (
Natural hosts. First intermediate hosts include several genera of freshwater snails. Second intermediate hosts are various freshwater fish. Definitive hosts are mammals, including cattle and carnivores. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected freshwater fish (
Site in human host. Small intestine (
Genus Heterophyes Cobbold, 1866
Heterophyes heterophyes (Siebold, 1853)
Heterophyes aegyptiaca Cobbold, 1866
Geographic distribution. Central and Southeast Asia, Japan, Middle East, North Africa (
Natural hosts. First intermediate hosts are various freshwater snails. Second intermediate hosts are various freshwater and brackish water fish. Definitive hosts are carnivores. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Heterophyes nocens Onji & Nishio, 1916
Heterophyes katsuradai Ozaki & Asada, 1926
Geographic distribution. Korea, Japan China (
Natural hosts. First intermediate hosts are freshwater snails in the genus Cerithidea. Second intermediate hosts are freshwater fish in the genus Acanthogobius. Definitive hosts are wild and domestic and felids. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Genus Heterophyopsis Tubangui & Africa, 1938
Heterophyopsis continua (Onki & Nishio, 1916)
Geographic distribution. Korea, Japan (
Natural hosts. First intermediate hosts are unknown. Second intermediate hosts are various freshwater fish. Definitive hosts are carnivores and birds. Zoonotic in humans(
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Genus Metagonimus Katsurada, 1912
Metagonimus katsuradai Izumi, 1935
Geographic distribution. Japan, Russia (
Natural hosts. First intermediate hosts are freshwater snails in the genus Semisulcospira. Second intermediate hosts are freshwater fish in the genus Tanakia. Definitive hosts are carnivores. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Metagonimus minutus Katsuta, 1932
Geographic distribution. Taiwan (
Natural hosts. First intermediate hosts are unknown. Second intermediate hosts are brackish water fish in the genus Mugil. Definitive hosts are unknown; presumed zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Metagonimus miyatai Saito et al., 1997
Geographic distribution. Korea, Japan (
Natural hosts. First intermediate hosts are freshwater snails in the genus Semisulcospira. Second intermediate hosts are various freshwater fish. Definitive hosts are carnivores, rodents, and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Metagonimus takahashii Takahashi, 1929
Geographic distribution. Korea, Japan (
Natural hosts. First intermediate hosts are freshwater snails in the genera Semisulcospira and Koreanomelania. Second intermediate hosts are various freshwater fish. Definitive hosts are carnivores and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Metagonimus yokogawai (Katsurada, 1912)
Geographic distribution. Central and Southeast Asia, Russia, Japan, Europe (
Natural hosts. First intermediate hosts are freshwater snails in the genus Semisulcospira. Second intermediate hosts are various freshwater fish. Definitive hosts are carnivores, rodents, and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Genus Procerovum Onji & Nishio, 1916
Procerovum calderoni (Africa & Garcia, 1935)
Geographic distribution. Egypt, Southeast Asia (
Natural hosts. First intermediate hosts are brackish water snails in the genus Sermyla. Second intermediate hosts are freshwater fish in the genus Ophiocephalis. Definitive hosts are wild and domestic canids and felids. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Procerovum varium Onji & Nishio, 1916
Geographic distribution. Korea, Japan (
Natural hosts. First intermediate hosts are brackish water snails in the genus Melanoides. Second intermediate hosts are brackish water fish in the genus Mugil. Definitive hosts are wild and domestic canids and felids. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Genus Pygidiopsis Looss, 1907
Pygidiopsis genata Looss, 1907
Geographic distribution. North Africa, Middle East, Eastern Europe, Philippines (
Natural hosts. First intermediate hosts are freshwater snails in the genera Melanoides and Melanopsis. Second intermediate hosts are various freshwater fish. Definitive hosts are carnivores, rodents, shrews, and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Pygidiopsis summa Onji & Nishio, 1916
Geographic distribution. Korea, Japan, Vietnam (
Natural hosts. First intermediate hosts are unknown. Second intermediate hosts are brackish water fish in the genera Mugil and Acnathogonius. Definitive hosts are wild and domestic felids. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Genus Stellantchasmus Onji & Nishio, 1916
Stellantchasmus falcatus Onji & Nishio, 1916
Geographic distribution. Central and Southeast Asia, Japan, Middle East, Australia, Hawaii (
Natural hosts. First intermediate hosts are freshwater snails in the genera Stenomelania and Thiara. Second intermediate hosts are mullets. Definitive hosts are wild and domestic canids and felids, rabbits, rats, and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Genus Stictodora Looss, 1899
Stictodora fuscata (Onji & Nishio, 1916)
Geographic distribution. Korea, Japan, Kuwait (
Natural hosts. First intermediate hosts are unknown. Second intermediate hosts are brackish water fish in the genera Acanthogobius and Pseudorasbora. Definitive hosts are wild and domestic canids and felids. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
Stictodora lari Yamaguti, 1939
Geographic distribution. Southeast Asia, Japan, Russia, Australia (
Natural hosts. First intermediate hosts are brackish water snails, including the genus Velacumantus. Second intermediate hosts are various brackish water fish. Definitive hosts are wild and domestic canids and felids. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Small intestine (
●●●●●●●●● Opisthorchiidae Looss, 1899
Genus Amphimerus Barker, 1911
Geographic distribution. North, Central, and South America (
Natural hosts. Intermediate hosts are various freshwater snails. Second intermediate hosts are freshwater fish. Natural hosts are a variety of mammals, birds, and reptiles, including domestic dogs and cats. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Liver (
Notes. The natural hosts and species identification have not been confirmed from human isolates, most of which have been documented in Ecuador.
Genus Clonorchis Looss, 1907
Clonorchis sinensis (Cobbold, 1875)
Geographic distribution. East Asia; hot spots of endemicity for human disease include Korea, China, Taiwan, and Vietnam (
Natural hosts. First intermediate hosts are various genera of freshwater snails. Second intermediate host are a variety of freshwater fish, primarily cyprinids. Definitive hosts are fish-eating mammals, including wild and domestic canids and felids, mustelids, and pigs. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Biliary ducts (
Genus Metorchis Looss, 1899
Metorchis bilis (Braun, 1790)
Distoma albidus Braun, 1893
Distoma crassiusculus Rudolphi, 1809
Geographic distribution. Central and Eastern Europe, Russia (
Natural hosts. First intermediate hosts include snails of the genus Bithynia. Second intermediate hosts are typically cyprinid fishes (e.g., carps, minnows). Natural definitive hosts are various fish-eating mammals and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Biliary ducts (
Metorchis conjunctus (Cobbold, 1860)
Geographic distribution. Northern North America (
Natural hosts. First intermediate hosts are freshwater snails in the genus Amnicola. Second intermediate hosts are freshwater fish, primarily members of the genus Catostomus. Definitive hosts are carnivores. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Biliary ducts (
Metorchis orientalis Tanabe, 1921
Geographic distribution. East Asia (
Natural hosts. First intermediate hosts include snails of the genera Bithynia and Parafossarulus. Second intermediate hosts are typically cyprinid fishes (e.g., carps, minnows). Natural definitive hosts are various fish-eating mammals and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Biliary ducts (
Metorchis taiwanensis Morishita & Tsuchimochi, 1952
Geographic distribution. East Asia (
Natural hosts. First intermediate hosts include snails of the genus Bithynia. Second intermediate hosts are typically cyprinid fishes (e.g., carps, minnows). Natural definitive hosts are various fish-eating mammals and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Biliary ducts (
Genus Opisthorchis Blanchard, 1895
Opisthorchis felineus (Rivolta, 1884)
Geographic distribution. Eastern Europe, Russia, Central Asia (
Natural hosts. First intermediate hosts are freshwater snails in the genus Bithynia. Second intermediate hosts are various freshwater fish. Definitive hosts are mammals, primarily carnivores. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Biliary ducts (
Opisthorchis viverrini (Poirier, 1886)
Geographic distribution. Southeast Asia, with high prevalence of human infection in Thailand, Laos, Vietnam, and Cambodia (
Natural hosts. First intermediate hosts are freshwater snails in the genus Bithynia. Second intermediate hosts are various freshwater fish. Definitive hosts are wild and domestic canids and felids. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Biliary ducts (
Genus Pseudamphistomum Lühe, 1908
Pseudamphistomum truncatum (Rudolphi, 1819)
Geographic distribution. Europe, Asia (
Natural hosts. First intermediate hosts are freshwater and brackish snails. Second intermediate host are freshwater, brackish, and marine fish, primarily cyprinids. Definitive hosts are carnivores, including cats, pinnipeds, and mustelids. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected fish (
Site in human host. Biliary ducts (
●●●●●●●● Pronocephalata Olson et al., 2003
●●●●●●●●● Paramphistomidae Fischoeder, 1901
Genus Fischoederius Stiles & Goldberger, 1910
Fischoederius elongatus (Poirier, 1883)
Geographic distribution. Europe, Russia, Central and Southeast Asia, Japan (
Natural hosts. First intermediate hosts are freshwater snails in the genus Lymnaea. Second intermediate hosts are freshwater plants. Definitive hosts are cattle, deer, goats, and sheep. Zoonotic in humans (
Route of infection. Ingestion of metacercariae on contaminated aquatic vegetation (
Site in human host. Small intestine (
Genus Gastrodiscoides Leiper, 1913
Gastrodiscoides hominis (Lewis & McConnell, 1876)
Geographic distribution. Europe, Central and Southeast Asia(Mas-Coma 2006;
Natural hosts. First intermediate hosts are freshwater snails in the genus Helicorbis. Second intermediate hosts are freshwater plants, amphibians, and crayfish. Definitive hosts are pigs and humans (Mas-Coma 2006;
Route of infection. Ingestion of metacercariae in infected intermediate hosts (Mas-Coma 2006;
Site in human host. Small intestine (Mas-Coma 2006;
Genus Watsonius Stiles & Goldberger, 1910
Watsonius watsoni (Conyngham, 1904)
Geographic distribution. Sub-Saharan Africa, Vietnam (
Natural hosts. First intermediate hosts are freshwater snails in the genus Physa. Second intermediate hosts are presumed to be freshwater vegetation. Definitive hosts are non-human primates. Zoonotic in humans (
Route of infection. Ingestion of metacercariae on contaminated aquatic vegetation (
Site in human host. Small intestine (
●●●●●●●● Xiphidiata Olson et al., 2003
●●●●●●●●● Dicrocoeliidae Looss, 1899
Genus Dicrocoelium Dujardin, 1845
Dicrocoelium dendriticum (Rudolphi, 1819)
Dicrocoelium lanceolatum Stiles & Hassall, 1898
Geographic distribution. North America, Africa, Asia, Europe, Middle East (
Natural hosts. First intermediate hosts are various genera of terrestrial snails. Second intermediate hosts are ants (primarily genus Formica). Definitive hosts are ungulates, including cattle, sheep, and goats. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected ants (
Site in human host. Bile ducts, gall bladder (
Dicrocoelium hospes Looss, 1907
Geographic distribution. West Africa (
Natural hosts. First intermediate hosts are snails in the genera Achatina and Limicolaria. Second intermediate hosts are ants in the genera Dorylus and Crematogaster. Definitive hosts are ungulates, including cattle and sheep. Zoonotic in humans (
Route of infection. Ingestion of infected intermediate hosts (
Site in human host. Bile ducts (
Notes. It is uncertain whether D. hospes causes true infection in humans. Most reported cases of the finding of eggs in stool are believed to be spurious after the consumption of infected beef liver (
●●●●●●●●● Lecithodendriidae Lühe, 1901
Genus Caprimolgorchis Jha, 1943
Caprimolgorchis molenkampi Lie Kian Joe, 1961
Geographic distribution. Southeast Asia (
Natural hosts. First intermediate hosts are unknown, but hypothesized to be freshwater snails in the genera Bithynia or Zebrina. Second intermediate hosts are dragonflies and damselflies. Definitive hosts are rodents and bats. Zoonotic in humans (
Route of infection. Ingestion of infected insects (
Site in human host. Small intestine (
●●●●●●●●● Microphalidae Ward, 1901
Genus Gynaecotyla Yamaguti, 1939
Gynaecotyla squatarolae (Yamaguti, 1934)
Geographic distribution. Japan, South Korea, Taiwan (
Natural hosts. First intermediate hosts are brackish water snails in the genus Batillaria. Second intermediate hosts are brackish water crabs in the genus Macrophthalmus. Definitive hosts are shorebirds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected crabs (
Site in human host. Small intestine (
Genus Microphallus Ward, 1901
Microphallus brevicaeca (Africa & Garcia, 1935)
Geographic distribution. Papua New Guinea, Philippines (
Natural hosts. First intermediate hosts are unknown. Second intermediate hosts are brackish water crustaceans in the genera Carcinus and Macrobrachium. Definitive hosts are birds and mammals, especially non-human primates. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected crustaceans (
Site in human host. Small intestine (
●●●●●●●●● Phaeneropsolidae Mehra, 1935
Genus Phaneropsolus Looss, 1899
Phaneropsolus bonnei Lie Kian Joe, 1951
Geographic distribution. Central and Southeast Asia (
Natural hosts. First intermediate hosts are unknown, but hypothesized to be freshwater snails in the genus Bithynia. Second intermediate hosts are dragonflies and damselflies. Definitive hosts are non-human primates. Zoonotic in humans (
Route of infection. Ingestion of infected insects (
Site in human host. Small intestine (
Phaneropsolus spinicirrus Kaewkes et al., 1991
Geographic distribution. Thailand (
Natural hosts. First intermediate hosts are unknown. Second intermediate hosts are unknown, but presumed to be dragonflies and damselflies. Definitive hosts are unknown; presumed zoonotic in humans (
Route of infection. Ingestion of infected intermediate hosts (
Site in human host. Small intestine (
●●●●●●●●● Plagiorchiidae Lühe, 1901
Genus Plagiorchis Lühe, 1899
Plagiorchis javensis Sandground, 1940
Geographic distribution. Indonesia (
Natural hosts. First intermediate hosts are unknown. Second intermediate hosts include snails, insects, and possibly fish. Definitive hosts are birds and bats. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate hosts (
Site in human host. Small intestine (
Plagiorchis muris (Tanabe, 1922)
Geographic distribution. Europe, Central and Southeast Asia, Japan, North and Central America (
Natural hosts. First intermediate hosts are freshwater snails in the genus Lymnaea. Second intermediate hosts are freshwater insects, crustaceans, and fish. Definitive hosts are canids, felids, raccoons, rodents, bats, and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate hosts (
Site in human host. Small intestine (
Plagiorchis philippinensis Africa & Garcia, 1937
Geographic distribution. Philippines (
Natural hosts. First intermediate hosts are unknown. Second intermediate hosts are presumed to be aquatic insects. Definitive hosts rodents and possibly birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate hosts (
Site in human host. Small intestine (
Plagiorchis vespertilionis (Müller, 1784)
Geographic distribution. Europe, North Africa, Central and Southeast Asia, Japan, Madagascar, North America (
Natural hosts. First intermediate hosts are freshwater snails in the genus Lymnaea. Second intermediate hosts are freshwater insects. Definitive hosts are rodents and bats. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected insect intermediate hosts (
Site in human host. Small intestine (
●●●●●●●● Troglotremata Schell, 1890
●●●●●●●●● Nanophyetidae Dollfus, 1939
Genus Nanophyetus Chapin, 1928
Nanophyetus salmincola (Chapin, 1926)
Geographic distribution. Northern North America (
Natural hosts. First intermediate hosts are snails in the genus Oxytrema. Second intermediate hosts are several general of freshwater fish, especially salmonids. Definitive hosts canids, felids, raccoons, and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate hosts (
Site in human host. Small intestine (
Nanophyetus schikhobalowi Skrjabin & Podiapolskaia, 1931
Geographic distribution. Northern Eurasia (
Natural hosts. First intermediate hosts are snails in the genus Oxytrema. Second intermediate hosts are several general of freshwater fish, especially salmonids. Definitive hosts canids, felids, raccoons, and birds. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate hosts (
Site in human host. Small intestine (
●●●●●●●●● Paragonimidae Dollfus, 1939
Genus Paragonimus Braun, 1899
Paragonimus africanus Volker & Vogel, 1965
Geographic distribution. West Africa (
Natural hosts. First intermediate hosts are presumed to be freshwater or brackish snails, but the specific species have yet to be identified. Second intermediate hosts are freshwater crabs in the family Potamidae. Definitive hosts are carnivores and non-human primates. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate or paratenic hosts (
Site in human host. Lungs, possibly ectopic infection at other sites (
Paragonimus heterotremus Chen & Hsia, 1964
Paragonimus tuanshansis Chung et al., 1964
Paragonimus pseudoheterotremus Waikagul et al., 2007
Geographic distribution. Southeast Asia (
Natural hosts. First intermediate hosts are freshwater snails in the superfamily Rissooidea. Second intermediate hosts are freshwater crabs in the families Potamidae and Parathelphusidae. Definitive hosts are carnivores and non-human primates. Wild boar, rodents, and deer can serve as paratenic hosts. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate or paratenic hosts (
Site in human host. Lungs, possibly ectopic infection at other sites (
Notes. Paragonimus heterotremus is often referred to as a species complex; the status of many members as distinct and valid species is an area of ongoing investigation.
Paragonimus kellicotti Ward, 1908
Geographic distribution. Eastern and Midwestern North America (
Natural hosts. First intermediate hosts are freshwater snails in the family Pomatiopsidae. Second intermediate hosts are freshwater crayfish, primarily of the family Astacidae. Definitive hosts are carnivores and marsupials. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate and paratenic hosts (
Site in human host. Lungs, possibly ectopic infection at other sites (
Paragonimus mexicanus Miyazaki & Ishii, 1968
Paragonimus peruvianus Miyazaki et al., 1969
Paragonimus ecuadorensis Voekler & Arzube, 1979
Geographic distribution. Central and South America (
Natural hosts. First intermediate hosts are freshwater and brackish snails in the families Hydrobiidae and Pomatiopsidae. Second intermediate hosts are freshwater crabs in the families Pseudothelphusidae and Trichodactylidae. Definitive hosts are carnivores and marsupials. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected crustaceans (
Site in human host. Lungs, possibly ectopic infection at other sites (
Paragonimus ohirai Miyazaki, 1939
Paragonimus iloktsuensis Chen, 1940
Paragonimus sadoensis Miyazaki et al., 1968
Geographic distribution. East Asia (
Natural hosts. First intermediate hosts are freshwater and brackish snails in the families Assimineidae and Pomatiopsidae. Second intermediate hosts are freshwater crabs in the family Potamidae and brackish crabs in the family Grapsidae. Definitive hosts are carnivores. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate or paratenic hosts (
Site in human host. Lungs, possibly ectopic infection at other sites (
Notes. Paragonimus ohirai is often referred to as a species complex; the status of many members as distinct and valid species is an area of ongoing investigation.
Paragonimus skrjabini Chen, 1959
Paragonimus miyazakii Kamo et al., 1961
Paragonimus szechuanensis Chung & Tsao, 1962
Paragonimus hueitungensis Chung et al., 1975
Paragonimus veocularis Chen & Li, 1979
Geographic distribution. East and Southeast Asia, Indian subcontinent (
Natural hosts. First intermediate hosts are freshwater and brackish snails in the superfamily Rissooidea. Second intermediate hosts are freshwater crabs in the families Potamidae and Parathelphusidae. Definitive hosts are carnivores. Wild boar, rodents, and deer may serve as paratenic hosts. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate and paratenic hosts (
Site in human host. Lungs, possibly ectopic infection at other sites (
Notes. Paragonimus skrjabini is often referred to as a species complex; the status of many members as distinct and valid species is an area of ongoing investigation.
Paragonimus uterobilateralis Volker & Vogel, 1965
Geographic distribution. West Africa (
Natural hosts. First intermediate hosts are presumed to be freshwater or brackish snails, but the specific species have yet to be identified. Second intermediate hosts are freshwater crabs in the family Potamidae. Definitive hosts are carnivores. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate or paratenic hosts (
Site in human host. Lungs, possibly ectopic infection at other sites (
Paragonimus westermani (Kerbert, 1878)
Distoma pulmonalis Baelz, 1880
Distoma ringeri Cobbold, 1880
Paragonimus edwardsi Gulati, 1926
Paragonimus macacae Sandosham, 1953
Paragonimus asymmetricus Chen, 1977
Paragonimus filipinus Miyazaki, 1978
Paragonimus philippinensis Ito et al., 1978
Geographic distribution. East and Southeast Asia, Indian subcontinent, Siberia (
Natural hosts. First intermediate hosts are freshwater and brackish snails in the superfamily Cerithioidea. Second intermediate hosts are freshwater crabs in the families Potamidae and Parathelphusidae. Definitive hosts are carnivores and non-human primates. Wild boar, rodents, and deer may serve as paratenic hosts. Zoonotic in humans (
Route of infection. Ingestion of metacercariae in infected intermediate or paratenic hosts (
Site in human host. Lungs, possibly ectopic infection at other sites (
Notes. Paragonimus westermani is often referred to as a species complex; the status of many members as distinct and valid species is an area of ongoing investigation.
●●●●●●●●● Orchipedidae Skrjabin, 1913
Achillurbainiidae Dollfus, 1939
Genus Achillurbainia Dolffus, 1939
Poikilorchis Fain & Vandepitte, 1957
Achillurbainia congolensis (Fain & Vandepitte, 1957)
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Unknown; presumed zoonotic in humans (
Route of infection. Unknown.
Site in human host. Subcutaneous cysts (usually near the ear), mastoid, middle ear (
Achillurbainia nouveli Dolffus, 1939
Geographic distribution. Southeast Asia (human case from China) (
Natural hosts. First intermediate hosts are unknown. Second intermediate hosts are freshwater crabs (Paratelphusa). Definitive hosts are leopards. Zoonotic in humans (
Route of infection. Unknown, presumed ingestion of metacercariae in undercooked crabs (
Site in human host. Subcutaneous cysts (near the ear) (
Achillurbainia recondita Travassos, 1942
Geographic distribution. Central and South America (
Natural hosts. Intermediate hosts unknown. Definitive hosts are opossums (Didelphis marsupialis). Zoonotic in humans (
Route of infection. Unknown.
Site in human host. Peritoneal cavity (
●●●● Ecdysozoa Anguinaldo et al., 1997
●●●●● Panarthropoda Nielsen, 1995
●●●●●● Arthropoda von Siebold, 1848
●●●●●●● Chelicerata Heymons, 1901
●●●●●●●● Euchelicerata Weygoldt & Paulus, 1979
●●●●●●●●● Arachnida Lamarck, 1801
●●●●●●●●●● Acari Leach, 1817
●●●●●●●●●●● Acariformes Zakhvatkin, 1952
●●●●●●●●●●●● Sarcoptiformes Reuter, 1909
●●●●●●●●●●●●● Astigmatina Canestrini, 1891
●●●●●●●●●●●●●● Acaridia Latreille, 1802
●●●●●●●●●●●●●●● Histiostomatidae Berlese, 1897
Histiostomatidae, incertae sedis
Geographic distribution. Unknown (single human case from Saudi Arabia) (
Natural hosts. Unknown
Route of infection. Unknown, presumed exposure to fresh water (
Site in human host. Ear (
Vectored pathogens. None
Notes. Histostomatid mites were isolated from the ear of a Saudi man who travelled to the United States in 2007. The mites were reported as being an undescribed species of Histiostomatidae close to Loxantoetus (
●●●●●●●●●●●●●●● Acaridae Latreille, 1802
Genus Sancassania Oudemans, 1916
Sancassania berlesei (Michael, 1903)
Geographic distribution. Worldwide (
Natural hosts. None; cause incidental infestations in humans (
Route of infection. Contamination from the environment.
Site in human host. Mastoid cavity, ear (
Vectored pathogens. None.
Genus Cosmoglyphus Oudemans, 1932
Geographic distribution. Worldwide (
Natural hosts. None; cause incidental infestations in humans (
Route of infection. Contamination from the environment.
Site in human host. Ear (
Vectored pathogens. None.
Notes. Isolates of Cosmoglyphus from human clinical specimens have not been characterized at the species level.
Genus Rhizoglyphus Claparédè, 1869
Geographic distribution. Worldwide (
Natural hosts. None; cause incidental infestations in humans (
Route of infection. Contamination from the environment
Site in human host. Ear (
Vectored pathogens. None
Notes. Rhizoglyphus from human clinical specimens have not been characterized at the species level.
●●●●●●●●●●●●●●● Chorotoglyphidae Berlese, 1897
Genus Chorotoglyphus Berlese, 1884
Chorotoglyphus arcuatus (Troupeau, 1879)
Geographic distribution. Worldwide (Abi-Akl 2017).
Natural hosts. None; cause incidental infections in humans (Abi-Akl 2017).
Route of infection. Contamination from the environment.
Site in human host. Ear (Abi-Akl 2017).
Vectored pathogens. None.
Notes. The species-level identification of C. arcuatus isolated from the ear of a man in Lebanon was considered tentative based on morphologic characteristics (Abi-Akl 2017).
●●●●●●●●●●●●●● Psoroptidia Yunker, 1955
●●●●●●●●●●●●●●● Pyroglyphidae Cunliffe, 1958
Genus Dermatophagoides Bogdanov, 1864
Dermatophagoides farinae Hughes, 1961
Geographic distribution. Worldwide, more prevalent in North America (
Natural hosts. None; cause incidental infections in humans (
Route of infection. Contamination from the environment.
Site in human host. Ear (
Vectored pathogens. None.
Notes. The finding of D. farinae in stool (
●●●●●●●●●●●●●●● Psoroptidae Canestrini, 1892
Genus Otodectes Canestrini, 1894
Otodectes cynotis (Hering, 1838)
Geographic distribution. Worldwide (
Natural hosts. Carnivores, primarily dogs, cats, and ferrets. Zoonotic in humans (
Route of infection. Contamination from the environment.
Site in human host. Ear (
Vectored pathogens. None.
Genus Psoroptes Gervais, 1841
Psoroptes ovis (Hering, 1838)
Geographic distribution. Worldwide (
Natural hosts. Mammals, primarily sheep, but also horses, cattle, goats. Zoonotic on humans (
Route of infection. Contact with infected animal hosts (
Site in human host. Skin (
Vectored pathogens. None.
●●●●●●●●●●●●●●● Sarcoptidae Murray, 1877
Genus Notoedres Railliet, 1893
Notoedres cati (Hering, 1838)
Geographic distribution. Worldwide (
Natural hosts. Cats and other felids. Zoonotic on humans (
Route of infection. Contact with infected felid hosts (
Site in human host. Skin (
Vectored pathogens. None.
Genus Sarcoptes Latreille, 1802
Sarcoptes scabiei (Linnaeus, 1758)
Geographic distribution. Worldwide (
Natural hosts. Humans (other animals have their own varieties and subspecies) (
Route of infection. Direct person-to-person contact or contaminated fomites (
Site in human host. Skin (
Vectored pathogens. None.
Genus Trixacarus Sellnick, 1944
Trixacarus caviae Fain et al., 1972
Geographic distribution. Worldwide (
Natural hosts. Domestic Guinea pigs. Zoonotic on humans (
Route of infection. Contact with infected Guinea pigs (
Site in human host. Skin (
Vectored pathogens. None.
●●●●●●●●●●●● Trombidiformes Reuter, 1909
●●●●●●●●●●●●● Prostigmata Kramer, 1877
●●●●●●●●●●●●●● Trombidoidea Leach, 1815
●●●●●●●●●●●●●●● Trombiculidae Ewing, 1929
Genus Eutrombicula Ewing, 1938
Eutrombicula alfreddugesi (Oudemans, 1910)
Geographic distribution. Western Hemisphere (
Natural hosts. Mammals and birds. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larvae in the environment (
Site in human host. Skin (
Vectored pathogens. None.
Eutrombicula sarcia (Womersley, 1944)
Geographic distribution. Asia, Australia (
Natural hosts. Mammals and birds. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larvae in the environment (
Site in human host. Skin.
Vectored pathogens. None.
Genus Leptotrombidium Nagayo et al., 1916
Leptotrombidium akamushi (Brumpt, 1910)
Geographic distribution. Japan (
Natural hosts. Rodents and insectivores. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larvae in the environment (
Site in human host. Skin.
Vectored pathogens. Orientia tsutsugamushi (Oriental scrub typhus) (
Leptotrombidium arenicola (Traub, 1960)
Geographic distribution. Malaysia (
Natural hosts. Rodents and insectivores. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larvae in the environment (
Site in human host. Skin.
Vectored pathogens. Orientia tsutsugamushi (Oriental scrub typhus) (
Leptotrombidium deliense (Walch, 1922)
Geographic distribution. Southeast Asia, Japan, Philippines, Australia, Pacific Islands (
Natural hosts. Rodents and insectivores. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larvae in the environment (
Site in human host. Skin.
Vectored pathogens. Orientia tsutsugamushi (Oriental scrub typhus) (
Leptotrombidium fletcheri (Womersley & Heaslip, 1943)
Geographic distribution. Malaysia (
Natural hosts. Rodents and insectivores. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larvae in the environment (
Site in human host. Skin.
Vectored pathogens. Orientia tsutsugamushi (Oriental scrub typhus) (
Leptotrombidium pallidum (Nagayo et al., 1919)
Geographic distribution. Japan (
Natural hosts. Rodents and insectivores. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larvae in the environment (
Site in human host. Skin
Vectored pathogens. Orientia tsutsugamushi (Oriental scrub typhus) (
Leptotrombidium pavlovskyi (Schluger, 1948)
Geographic distribution. Eastern Russia (
Natural hosts. Rodents and insectivores. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larvae in the environment (
Site in human host. Skin
Vectored pathogens. Orientia tsutsugamushi (Oriental scrub typhus) (
Leptotrombidium scutellaris (Nagayo et al., 1921)
Geographic distribution. Japan (
Natural hosts. Rodents and insectivores. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larvae in the environment (
Site in human host. Skin
Vectored pathogens. Orientia tsutsugamushi (Oriental scrub typhus) (
Genus Neotrombicula Hirst, 1925
Neotrombicula autumnalis (Shaw, 1790)
Geographic distribution. Europe (
Natural hosts. Mammals and birds. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larvae in the environment (
Site in human host. Skin.
Vectored pathogens. None.
Genus Schoengastiella Hirst, 1915
Schoengastiella ligula Radford, 1946
Geographic distribution. South Asia (
Natural hosts. Rodents and insectivores. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larvae in the environment (
Site in human host. Skin
Vectored pathogens. Orientia tsutsugamushi (Oriental scrub typhus) (
●●●●●●●●●●●●●● Cheyletoidea Leach, 1815
●●●●●●●●●●●●●●● Cheyletidae Leach, 1815
Genus Cheyletiella Canestrini, 1886
Cheyletiella blakei Smikey, 1970
Geographic distribution. Worldwide (
Natural hosts. Cats. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to infected cats (
Site in human host. Skin (
Vectored pathogens. None.
Cheyletiella parasitovorax Mégnin, 1877
Geographic distribution. Worldwide (
Natural hosts. Rabbits. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to infected rabbits (
Site in human host. Skin (
Vectored pathogens. None.
Cheyletiella yasguri Smiley, 1965
Geographic distribution. Worldwide (
Natural hosts. Dogs. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to infected dogs (
Site in human host. Skin (
Vectored pathogens. None.
●●●●●●●●●●●●●●● Demodecidae Nicolet, 1855
Genus Demodex Owen, 1843
Demodex brevis Akbulatova, 1963
Geographic distribution. Worldwide (
Natural hosts. Humans (
Route of infection. Direct person-to-person contact (
Site in human host. Skin, sebaceous glands (
Vectored pathogens. None.
Demodex folliculorum Simon, 1842
Geographic distribution. Worldwide (
Natural hosts. Humans (
Route of infection. Direct person-to-person contact (
Site in human host. Skin, hair follicles (
Vectored pathogens. None.
●●●●●●●●●●●●●● Tarsonemoidea Kramer, 1877
●●●●●●●●●●●●●●● Pyemotidae Oudemans, 1937
Genus Pyemotes Amerling, 1861
Pyemotes herfsi (Oudemans, 1936)
Geographic distribution. North America, Europe, North Africa, India, Australia (
Natural hosts. Insects. Zoonotic on humans as incidental hosts (
Route of infection. Environmental exposure (
Site in human host. Skin (
Vectored pathogens. None.
Pyemotes tritici (LaGrèze-Fossat & Montagné, 1851)
Geographic distribution. Worldwide (
Natural hosts. Insects. Zoonotic on humans as incidental hosts (
Route of infection. Environmental exposure (
Site in human host. Skin (
Vectored pathogens. None.
Pyemotes ventricosus (Newport, 1850)
Geographic distribution. Southern Europe (
Natural hosts. Insects. Zoonotic on humans as incidental hosts (
Route of infection. Environmental exposure (
Site in human host. Skin (
Vectored pathogens. None.
●●●●●●●●●●● Parasitiformes Leach, 1815
●●●●●●●●●●●● Ixodoidea Leach, 1815
●●●●●●●●●●●●● Ixodidae Koch, 1844
Genus Amblyomma Koch, 1844
Amblyomma americanum (Linnaeus, 1758)
Ixodes unipunctata Packard, 1869
Geographic distribution. Eastern North America (Cooley 1944;
Natural hosts. Many birds and mammals, including humans (Cooley 1944;
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Ehrlichia chaffeensis (human monocytic ehrlichiosis), E. ewingii (human granulocytic ehrlichiosis), Francisella tularensis (tularemia), Heartland virus, Bourbon virus; also implicated in alpha-gal syndrome and Southern Tick-Associated Rash Illness (STARI) (
Amblyomma aureolatum (Pallas, 1772)
Amblyomma striatum Koch, 1844
Geographic distribution. South America (
Natural hosts. Mammals, including carnivores and rodents, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia rickettsii (Rocky Mountain Spotted Fever) (
Amblyomma babirussae Schülze, 1933
Geographic distribution. Indonesia (
Natural hosts. Mammals, including pigs, bovids, deer, carnivores, and rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma brasiliense Aragão, 1908
Geographic distribution. South America (
Natural hosts. Several mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma breviscutatum Neumann, 1899
Amblyomma cyprium Koch & Neumann, 1899
Amblyomma cyprium aeratipes Schülze, 1932
Geographic distribution. Southeast Asia, Australia, Pacific Islands (
Natural hosts. Immature stages primarily on rodents and small birds. Adults are primarily on mammals, including bovids, deer, pigs, horses. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma cajennense (Fabricius, 1787)
Geographic distribution. Southern United States, Central and South America, Caribbean (Cooley 1944;
Natural hosts. Many mammals, including humans, and birds (Cooley 1944;
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma calcartum Neumann, 1899
Geographic distribution. Central and South America, Caribbean (
Natural hosts. Mammals, primarily anteaters; also birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma clypeolatum Neumann, 1899
Geographic distribution. India, Sri Lanka, Myanmar (
Natural hosts. Reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma coelebs Neumann, 1899
Geographic distribution. Central and South America (
Natural hosts. Several groups of mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma cohaerens Dönitz, 1909
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Primarily bovids, but also other mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma cordiferum Neumann, 1899
Geographic distribution. Southeast Asia (Audy 1960).
Natural hosts. Immature stages are primarily on rodents. Adults are on reptiles and ungulates. Zoonotic on humans (Audy 1960).
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Notes. The single record of A. cordiferum from a human in Malaysia (Audy 1960) is considered a tentative identification (
Amblyomma dissimile Koch, 1844
Geographic distribution. North, Central, and South America and Caribbean (Cooley 1944;
Natural hosts. Primarily reptiles and amphibians, but also a variety of mammals and birds. Zoonotic on humans (Cooley 1944;
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma dubitatum Neumann, 1899
Amblyomma cooperi Nuttall & Warburton, 1908
Geographic distribution. South America (
Natural hosts. Primarily rodents, but also other mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma falsomarmoreum Tonelli-Rondelli, 1935
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Reptiles, occasionally other mammals. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma fuscum Neumann, 1907
Geographic distribution. Brazil (
Natural hosts. Immature stages on mammals, including rodents, carnivores, and marsupials. Adults usually on reptiles and amphibians. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma gemma Dönitz, 1909
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Immature stages on small mammals and birds. Adults primarily on bovids, pigs, camels, and horses, but also other mammals, large birds, and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma geomydae (Cantor, 1847)
Amblyomma malayanum Neumann, 1906
Geographic distribution. Southeast Asia (
Natural hosts. Immature stages on a variety of small mammals, birds, and reptiles. Adults primarily on tortoises, but also several mammals, including pigs, bovids, deer. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma hadanii Nava et al., 2014
Geographic distribution. Argentina (
Natural hosts. Primarily bovids, tapirs, horses, also carnivores. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma hebraeum Koch, 1844
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Mammals, including bovids, goats, sheep, other ruminants, and humans; occasionally birds and reptiles (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia africae (African tick bite fever) (
Amblyomma incisum Neumann, 1906
Geographic distribution. South America (
Natural hosts. Mammals, primarily tapirs, but also rodents, deer, and carnivores. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma inoratum (Banks, 1909)
Geographic distribution. North and Central America (
Natural hosts. Several groups of mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma integrum Karsch, 1879
Geographic distribution. India, Sri Lanka (
Natural hosts. Primarily bovids, but also other mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin, ears (
Vectored pathogens. None.
Amblyomma javanense (Supino, 1897)
Aponomma sublaeve Neumann, 1899
Geographic distribution. Central, Southeastern Asia (
Natural hosts. Mammals, primarily pangolins, but also rodents, and carnivores, and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma latepunctatum Tonelli-Rondelli, 1939
Geographic distribution. South America (
Natural hosts. Mammals, primarily tapirs and peccaries, also marsupials and rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma latum Koch, 1844
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Primarily reptiles, also amphibians, rodents, and shrews. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ambylomma lepidum Dönitz, 1909
Geographic distribution. Sub-Saharan Africa, Middle East (
Natural hosts. Primarily bovids, but also other mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma limbatum Neumann, 1899
Geographic distribution. Australia (
Natural hosts. Reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma loculosum Neumann, 1907
Geographic distribution. Sub-Saharan Africa, Australia, several islands in the Indian and South Pacific Oceans (
Natural hosts. Primarily birds and reptiles, occasionally bovids. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma longirostre (Koch, 1844)
Geographic distribution. Central and South America (
Natural hosts. Primarily birds (immature stages) and New World porcupines (adults), but also a variety of mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma maculatum Koch, 1844
Geographic distribution. Southern USA, Central and South America (Cooley 1944;
Natural hosts. Many reptiles, birds, and mammals, including humans (Cooley 1944;
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia parkeri (tidewater spotted fever) (
Amblyomma marmoreum Koch, 1844
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Immature stages primarily on birds and mammals. Adults on tortoises. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma mixtum Koch, 1844
Geographic distribution. Southern USA, Central and South America (Cooley 1944;
Natural hosts. Variety of mammals, including humans, also birds, amphibians, reptiles (Cooley 1944;
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia rickettsii (Rocky Mountain spotted fever) (
Amblyomma moreliae (Koch, 1867)
Geographic distribution. Australia (
Natural hosts. Reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma naponense (Packard, 1869)
Amblyomma mantiquirense Aragão, 1908
Geographic distribution. Central and South America (
Natural hosts. Primarily mammals, including peccaries, carnivores, anteaters, marsupials, and rodents, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma neumanni Ribaga, 1902
Amblyomma furcula Dönitz, 1909
Geographic distribution. Argentina, Colombia (
Natural hosts. Mammals, including bovids, deer, carnivores, pigs, peccaries, and humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma nuttalli Dönitz, 1909
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Immature stages on a variety of mammals, birds, and reptiles. Adults primarily on tortoises. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ambylomma oblongoguttatum Koch, 1844
Geographic distribution. Central and South America (
Natural hosts. A variety of mammals, including deer, rodents, carnivores, and marsupials, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma ovale Koch, 1844
Amblyomma fossum Neumann, 1899
Geographic distribution. Southern USA, Central and South America (Cooley 1944;
Natural hosts. Mammals, primarily carnivores, rodents, tapirs, and humans. Occasionally marsupials, birds (Cooley 1944;
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma pacae Aragão, 1911
Geographic distribution. Central and South America (
Natural hosts. Primarily mammals, including rodents and marsupials, but also carnivores and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ambylomma parkeri Fonseca & Aragão, 1951
Geographic distribution. Brazil (
Natural hosts. Primarily rodents, also carnivores, marsupials, monkeys, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma parvum Aragão, 1908
Geographic distribution. Central and South America (
Natural hosts. Wide variety of mammals, including humans, and birds (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma paulopunctatum Neumann, 1899
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Mammals, primarily pigs, but also hippopotamuses, carnivores, and rodents, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma pecarium Dunn, 1933
Geographic distribution. Central and South America (
Natural hosts. Peccaries, also deer. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma personatum Neumann, 1901
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Rhinoceroses, bovids. Zoonotic on humans(
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma postoculatum Neumann, 1899
Geographic distribution. Australia (
Natural hosts. Marsupials. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma pseudoconcolor Aragão, 1908
Geographic distribution. South America (
Natural hosts. Primarily armadillos, also marsupials and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma pseudoparvum Guglielmone et al., 1990
Geographic distribution. Argentina (
Natural hosts. Caviomorph rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma romitii Tonelli-Rondelli, 1939
Amblyomma tasquei Floch & Adonnenc, 1940
Geographic distribution. South America (
Natural hosts. Rodents, marsupials. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma rotundum Koch, 1844
Geographic distribution. Southern USA, Central and South America, Pacific Islands (Cooley 1944;
Natural hosts. Reptiles and amphibians, occasionally birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma sabanerae Stoll, 1890
Geographic distribution. Central and South America (
Natural hosts. Primarily reptiles, including tortoises, also amphibians, rodents, and marsupials. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma scalpturatum Neumann, 1906
Geographic distribution. Central and South America (
Natural hosts. Mammals, including tapirs, pigs, anteaters, peccaries, carnivores, and rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma sculptum (Berlese, 1888)
Geographic distribution. South America (
Natural hosts. Several mammals, including capybaras and humans, and birds (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment
Site in human host. Skin.
Vectored pathogens. Rickettsia rickettsii (Rocky Mountain Spotted Fever) (
Amblyomma sparsum Neumann, 1899
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Several groups of mammals, birds, and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma tapirellum Dunn, 1933
Geographic distribution. Central and South America (
Natural hosts. Tapirs, peccaries, marsupials, rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma tenellum Koch, 1844
Amblyomma imitator Kohls, 1958
Geographic distribution. Southern USA, Central America (
Natural hosts. Mammals, including bovids, peccaries, horses, marsupials, carnivores, and rodents, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma testudinarum Koch, 1844
Geographic distribution. Central and Southeast Asia, Japan (
Natural hosts. Several groups of mammals, including humans, birds, and reptiles (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment
Site in human host. Skin, ear (
Vectored pathogens. Dabie bandavirus (severe fever with thrombocytopenia syndrome Virus, SFTSV) (
Amblyomma tholloni Neumann, 1899
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Several groups of mammals, primarily elephants, and birds and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma tigrinum Koch, 1844
Geographic distribution. South America (
Natural hosts. Primarily carnivores, also rodents and ungulates. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma tonelliae Nava et al., 2014
Geographic distribution. South America (
Natural hosts. Mammals, primarily bovids and equids. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia ricketsii (Rocky Mountain spotted fever) (
Amblyomma triguttatum Koch, 1844
Geographic distribution. Australia (
Natural hosts. Primarily marsupials, also horses, bovids, carnivores, lagomorphs, rodents, humans, and reptiles (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma triste Koch, 1844
Geographic distribution. Southern USA, Central and South America (Cooley 1944;
Natural hosts. Several groups of mammals, primarily bovids, deer, and carnivores, and birds. Zoonotic on humans (Cooley 1944;
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia parkeri (Tidewater spotted fever) (
Amblyomma tuberculatum Marx in Hubbard, 1894
Geographic distribution. Southeastern USA (Cooley 1944;
Natural hosts. Tortoises. Zoonotic on humans (Cooley 1944;
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Amblyomma variegatum (Fabricius, 1794)
Geographic distribution. Africa, Middle East, Caribbean (
Natural hosts. Several groups of mammals, primarily bovids, also humans, birds, and reptiles (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia africae (African tick bite fever) (
Amblyomma varium Koch, 1844
Geographic distribution. Central and South America (
Natural hosts. Mammals, primarily sloths, also marsupials, tapirs, carnivores, and rodents, also reptiles and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Genus Bothriocroton Keirans et al., 1994
Bothriocroton auruginans (Schülze, 1938)
Geographic distribution. Australia (
Natural hosts. Marsupials, occasionally carnivores. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Bothriocroton hydrosauri (Denny, 1843)
Geographic distribution. Australia (
Natural hosts. Reptiles, occasionally bovids. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Genus Dermacentor Koch, 1844
Dermacentor albipictus (Packard, 1869)
Ixodes nigrolineatus Packard, 1869
Geographic distribution. North and Central America (
Natural hosts. Mammals, primarily cattle, deer, and horses. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Babesia duncani (babesiosis) (
Dermacentor andersoni Stiles, 1908
Dermacentor venustus Marx in Neumann 1897
Geographic distribution. Rocky Mountain region of North America (
Natural hosts. Mammals, including humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment
Site in human host. Skin
Vectored pathogens. Rickettsia rickettsii (Rocky Mountain spotted fever), Francisella tularensis (tularemia), Colorado tick fever virus; also implicated in tick paralysis (
Dermacentor atrosignatus Neumann, 1906
Geographic distribution. Southeast Asia (
Natural hosts. Pigs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin, ear (
Vectored pathogens. None.
Dermacentor auratus Supino, 1897
Geographic distribution. Southeast Asia (
Natural hosts. Primarily pigs, but also a variety of other mammals, birds, and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin, ear (
Vectored pathogens. Rickettsia sibirica (Siberian tick typhus) (
Dermacentor bellulus (Schülze, 1933)
Geographic distribution. Southeast Asia (
Natural hosts. Immature stages primarily on rodents, also tree shrews, carnivores, lagomorphs, and birds. Adults are primarily on pigs, also carnivores. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Dermacentor circumguttatus Neumann, 1897
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Primarily elephants, also duikers, pigs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Dermacentor compactus Neumann, 1901
Geographic distribution. Southeast Asia (
Natural hosts. Primarily pigs, but also a variety of other mammals and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin, ear (
Vectored pathogens. None.
Dermacentor hunteri Bishopp, 1912
Geographic distribution. Southeast Asia (
Natural hosts. Primarily bovids, also deer, lagomorphs, and rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Dermacentor imitans Warburton, 1933
Geographic distribution. Central and South America (
Natural hosts. Peccaries, deer. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Dermacentor latus Cooley, 1937
Geographic distribution. Central America (
Natural hosts. Primarily tapirs, also carnivores. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Dermacentor limbooliati Apanaskevich & Apanaskevich, 2015
Geographic distribution. Malaysia, Vietnam (
Natural hosts. Pigs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Dermacentor marginatus (Sulzer, 1776)
Geographic distribution. Europe, western and central Asia, northern Africa (
Natural hosts. Many mammals, including humans, and birds (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia raoultii, Omsk hemorrhagic fever virus (
Dermacentor nitens Neumann, 1897
Geographic distribution. Southern USA, Central and South America, Caribbean (
Natural hosts. Horses, occasionally other mammals, reptiles, and amphibians. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Dermacentor niveus Neumann, 1897
Geographic distribution. Central Asia, China, Russia (
Natural hosts. Mammals, including ungulates, rodents, lagomorphs, hedgehogs, and carnivores. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Dermacentor nuttalli Olenev, 1929
Geographic distribution. Eastern Russia, Mongolia, China (
Natural hosts. Immature stages on rodents, lagomorphs, hedgehogs. Adults primarily on ungulates and horses. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia sibirica (Siberian tick typhus), Francisella tularensis (tularemia), Crimean-Congo hemorrhagic fever virus (
Dermacentor occidentalis Marx in Curtice, 1892
Geographic distribution. Pacific coastal areas of Mexico and USA (
Natural hosts. Several groups of mammals. Immature stages primarily on rodents and lagomorphs. Adults on cattle, deer, and humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia phlipii (Pacific Coast tick fever) (
Dermacentor parumapertus Neumann, 1901
Geographic distribution. North America (
Natural hosts. Lagomorphs, rodents, bovids, deer, carnivores, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Dermacentor raskemensis Pomerantsev, 1946
Geographic distribution. Central and Southeast Asia (
Natural hosts. Bovids, carnivores, rodents, lagomorphs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Dermacentor reticulatus (Fabricius, 1794)
Dermacentor pictus Hermann, 1804
Geographic distribution. Europe and western Asia (
Natural hosts. Immature stages primarily on rodents, lagomorphs, hedgehogs, rarely birds and reptiles, and amphibians. Adults primarily on canids, also ungulates, and humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia slovaca (tick-borne lymphandenopathy, TIBOLA), Rickettsia raoultii, Omsk hemorrhagic fever virus (
Dermacentor rhinocerinus (Denny, 1843)
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Primarily rhinoceroses, occasionally other mammals and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Dermacentor silvarum Olenev, 1931
Dermacentor asiaticus Emel’yanova & Kozlovskaya, 1967
Geographic distribution. Eastern Russia, China, Mongolia (
Natural hosts. Mammals, including bovids, deer, sheep, dogs, and humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia sibirica (Siberian tick typhus), Rickettsia raoultii (
Dermacentor similis Lado, Glon, et Klompen, 2021
Geographic distribution. North America, west of the Rocky Mountains (
Natural hosts. Several groups of mammals, including humans, and birds (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia rickettsii (Rocky Mountain spotted fever), Francisella tularensis (tularemia); also implicated in tick paralysis (
Dermacentor steini (Schülze, 1933)
Geographic distribution. Southeast Asia (
Natural hosts. Primarily pigs, but also a variety of other mammals and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin, ear (
Vectored pathogens. None.
Dermacentor tamokensis Apanaskevich & Apanaskevich, 2016
Geographic distribution. Southeast Asia (
Natural hosts. Pigs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Dermacentor variabilis (Say, 1821)
Dermacentor electus Koch, 1844
Geographic distribution. Eastern North America (
Natural hosts. Several groups of mammals, including humans, and birds. (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin, ear (
Vectored pathogens. Rickettsia rickettsii (Rocky Mountain spotted fever), Francisella tularensis (tularemia); also implicated in tick paralysis (
Genus Haemaphysalis Koch, 1844
Haemaphysalis aculeata Lavarra, 1904
Geographic distribution. India, Sri Lanka (
Natural hosts. Chevrotains, bovids, deer. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Kyasanur Forest Disease virus (
Haemaphysalis anomala Warburton, 1913
Geographic distribution. Southeast Asia (
Natural hosts. Immature stages on rodents and small birds. Adults on bovids, deer, carnivores. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis aponommoides Warburton, 1913
Geographic distribution. China, India, Nepal (
Natural hosts. Immature stages on rodents, shrews, birds. Adults on mammals, primarily bovids. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis bancrofti Nuttall & Warburton, 1915
Geographic distribution. Australia, Indonesia, Papua New Guinea (
Natural hosts. Primarily marsupials, but also a variety of other mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis birmaniae Supino, 1897
Geographic distribution. Southeast Asia (
Natural hosts. Bovids, deer, pigs, carnivores, and rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis bispinosa Neumann, 1897
Geographic distribution. Central and Southeast Asia (
Natural hosts. Mammals, primarily bovids and carnivores, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Kyasanur Forest disease virus (
Haemaphysalis campanulata Warburton, 1908
Geographic distribution. Central and Southeast Asia, Japan (
Natural hosts. Immature stages primarily on rodents. Adults on mammals, primarily carnivores. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis caucasica Olenev, 1928
Geographic distribution. Eastern Europe, Central Asia (
Natural hosts. Mammals, including lagomorphs, carnivores, rodents, and bovids, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis celebensis Hoogstral et al., 1965
Geographic distribution. Indonesia (
Natural hosts. Primarily pigs, bovids, deer, and horses. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis chordeilis (Packard, 1869)
Geographic distribution. North America (
Natural hosts. Primarily birds, also mammals including bovids, horses, rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis colasbelcouri (Santos Dias, 1958)
Geographic distribution. China, Vietnam, Laos (
Natural hosts. Primarily bovids and deer. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis concinna Koch, 1844
Geographic distribution. Palearctic (
Natural hosts. Small mammals, birds, and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Francisella tularensis (tularemia), tick-borne encephalitis viruses (TBE) (
Haemaphysalis cornigera Neumann, 1897
Geographic distribution. Southeast Asia, Japan (
Natural hosts. Mammals, including bovids, deer, carnivores, shrews, and tree shrews. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia japonica (Japanese spotted fever) (
Haemaphysalis cuspidata Warburton, 1910
Geographic distribution. India, Sri Lanka (
Natural hosts. Many groups of mammals, including ungulates, carnivores, rodents, lagomorphs, shrews, and non-human primates, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Kyasanur Forest disease virus (
Haemaphysalis darjeeling Hoogstraal & Dhanda, 1970
Geographic distribution. Southeast Asia (
Natural hosts. Mammals, including bovids, deer, pigs, and carnivores. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis doenitzi Warburton & Nuttall, 1909
Geographic distribution. Southeast Asia, Japan, Russia, Australia (
Natural hosts. Primarily birds, occasionally lagomorphs and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis elliptica (Koch, 1844)
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Primarily carnivores, also rodents, elephant shrews, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis elongata Neumann, 1897
Geographic distribution. Madagascar (
Natural hosts. Primarily tenrecs, also carnivores and hedgehogs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis erinacei Pavesi, 1884
Haemaphysalis numidiana Neumann, 1905
Haemaphysalis erinacei taurica Pospelova-Shtrom, 1939
Geographic distribution. Europe, northern Africa, Russia (
Natural hosts. Mammals, primarily hedgehogs and carnivores, also lagomorphs and bovids, birds, and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis flava Neumann, 1897
Geographic distribution. East Asia (
Natural hosts. Several groups of mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia japonica (Japanese spotted fever) (
Haemaphysalis heinrichi Schülze, 1939
Geographic distribution. Southeast Asia (
Natural hosts. Mammals, including bovids, carnivores, rodents, and shrews. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis hirsuta Hoogstraal et al., 1966
Geographic distribution. Indonesia (
Natural hosts. Mammals, including bovids, pigs, carnivores, and rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis hoodi Warburton & Nuttall, 1909
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Primarily birds, also mammals including bovids, non-human primates, rodents, carnivores, and lagomorphs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis humerosa Warburton & Nuttall, 1909
Geographic distribution. Indonesia, Australia (
Natural hosts. Primarily marsupials, also monotremes, rodents, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis hylobatis Schülze, 1933
Geographic distribution. Southeast Asia, Japan (
Natural hosts. Several groups of mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis hystricis Supino, 1897
Haemaphysalis nishiyamai Sugimoto, 1935
Haemaphysalis trispinosa Tounamoff, 1941
Geographic distribution. Southeast Asia, Japan (
Natural hosts. Several groups of mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia japonica (Japanese spotted fever) (
Haemaphysalis indoflava Dhanda & Bhat, 1968
Geographic distribution. Southeast Asia, Japan (
Natural hosts. Bovids, pigs, carnivores. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis inermis Birula, 1895
Geographic distribution. Southern Europe, Middle East (
Natural hosts. Primarily birds, also rodents, shrews, and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis intermedia Warburton & Nuttall, 1909
Geographic distribution. Central Asia (
Natural hosts. Several groups of mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis japonica Warburton, 1908
Haemaphysalis japonica douglasi Nuttall & Warburton, 1915
Geographic distribution. Southeast Asia, Japan, Russia (
Natural hosts. Mammals, including deer, carnivores, lagomorphs, pigs, horses, bovids, and hedgehogs, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis juxtakochi Cooley, 1946
Haemaphysalis kohlsi Aragão & Fonseca, 1951
Geographic distribution. USA, Central and South America (
Natural hosts. Mammals, including deer, peccaries, bovids, horses, carnivores, marsupials, rodents, and lagomorphs, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis kitaokai Hoogstraal, 1969
Geographic distribution. Southeast Asia, Japan (
Natural hosts. Mammals, including bovids, deer, horses, and rodents, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis koningsbergeri Warburton & Nuttall, 1909
Geographic distribution. Southeast Asia (
Natural hosts. Mammals, primarily carnivores and rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis lagrangei Larrousse, 1925
Haemaphysalis hystricis indochinensis Phan Trong, 1977
Geographic distribution. Southeast Asia (
Natural hosts. Several groups of mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis leachi (Audouin, 1826)
Geographic distribution. Africa (
Natural hosts. Mammals, primarily carnivores, bovids, pigs, non-human primates, hedgehogs, and rodents, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia conorii (boutonneuse fever) (
Haemaphysalis leporispalustris Packard, 1869
Geographic distribution. North, Central, and South America (
Natural hosts. Primarily rabbits, also other mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis longicornis Neumann, 1901
Geographic distribution. East Asia, Australia, New Zealand, Pacific Islands, eastern North America (
Natural hosts. Mammals, including sheep, deer, and horses, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin, ear (
Vectored pathogens. Dabie bandavirus (severe fever with thrombocytopenia syndrome vrus, SFTSV), Rickettsia japonica (Japanese spotted fever) (
Haemaphysalis mageshimaensis Saito & Hoogstraal, 1973
Geographic distribution. Southeast Asia, Japan (
Natural hosts. Mammals, including bovids, deer, carnivores, pigs, rodents, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis megaspinosa Saito, 1969
Geographic distribution. Southeast Asia, Japan (
Natural hosts. Deer, carnivores, horses. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis mjoebergi Warburton, 1926
Geographic distribution. Indonesia (
Natural hosts. Deer, bovids. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis montgomeryi Nuttall, 1912
Geographic distribution. Central and Southeast Asia, Japan (
Natural hosts. Mammals, including bovids, rodents, camels, deer, horses, and hedgehogs, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis nadchatrami Hoogstraal et al., 1965
Geographic distribution. Southeast Asia (
Natural hosts. Rodents, bovids, deer, pigs, carnivores, horses, tapirs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis nepalensis Hoogstraal, 1962
Geographic distribution. Central and Southeast Asia (
Natural hosts. Bovids, carnivores, rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis novaeguineae Hirst, 1914
Geographic distribution. Australia, Papua New Guinea (
Natural hosts. Mammals, including bovids, pigs, marsupials, carnivores, horses, and rodents, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis obesa Larrousse, 1925
Geographic distribution. Southeast Asia (
Natural hosts. Several groups of mammals. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis papuana Thorell, 1883
Geographic distribution. Southeast Asia (
Natural hosts. Mammals, including pigs, deer, musk deer, carnivores, and rodents, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis paraleachi Camicas et al. 1983
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Carnivores, rodents, bovids, non-human primates. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis parmata Neumann, 1905
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Mammals, primarily bovids, rarely reptiles and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis parva (Neumann, 1897)
Haemaphysalis otophila Schülze, 1919
Geographic distribution. Europe, northern Africa, western Asia (
Natural hosts. Mammals, including hedgehogs, carnivores, lagomorphs, rodents, and humans, birds, and reptiles (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis punctata Canestrini & Fanzago, 1878
Haemaphysalis punctata autumnalis Schülze, 1919
Geographic distribution. Europe, northern Africa, western and central Asia (
Natural hosts. Several groups of mammals, including humans, birds, and reptiles (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis qinghaiensis Teng, 1980
Geographic distribution. China (
Natural hosts. Bovids, horses, lagomorphs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis ramachandrai Dhanda et al., 1970
Geographic distribution. India, Nepal (
Natural hosts. Deer, bovids, carnivores. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis roubaudi Toumanoff, 1940
Geographic distribution. Vietnam (
Natural hosts. Deer. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis semermis Neumann, 1901
Geographic distribution. Southeast Asia (
Natural hosts. Chevrotains, deer, pigs, carnivores, tapirs, rodents, tree shrews. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis shimoga Trapido & Hoogstraal, 1964
Haemaphysalis cornigera vietnama Phan Trong, 1977
Geographic distribution. Southeast Asia (
Natural hosts. Mammals, including bovids, pigs, deer, and rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis silacea Robinson, 1912
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Mammals, including bovids, elephant shrews, rhinoceroses, carnivores, lagomorphs, and rodents, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis spinigera Neumann, 1897
Geographic distribution. Southeast Asia (
Natural hosts. Several groups of mammals, including humans, and birds (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Kyasanur Forest Disease virus (
Haemaphysalis sulcata Canestrini & Fanzago, 1878
Haemaphysalis cholodkovskyi Olenev. 1928
Geographic distribution. Europe, North Africa, Asia (
Natural hosts. Mammals, primarily bovids, but also carnivores, rodents, lagomorphs, bats, hedgehogs, and humans, and reptiles (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Haemaphysalis turturis Nuttall & Warburton, 1915
Geographic distribution. India, Sri Lanka (
Natural hosts. Several groups of mammals, birds, and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Kyasanur Forest disease virus (
Haemaphysalis wellingtoni Nuttall & Warburton, 1908
Geographic distribution. Southeast Asia (
Natural hosts. Primarily birds, occasionally mammals. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Kyasanur Forest disease virus (
Genus Hyalomma Koch, 1844
Hyalomma aegyptium (Linnaeus, 1758)
Geographic distribution. Europe, North Africa, Middle East, Central Asia (
Natural hosts. Primarily tortoises, but also other reptiles and mammals. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Borrelia turcica (tick-borne relapsing fever) (
Hyalomma albiparmatum Schülze, 1919
Geographic distribution. East Africa (
Natural hosts. Many mammals, primarily wild ungulates, also lagomorphs and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia conorii (boutonneuse fever) (
Hyalomma anatolicum Koch, 1844
Geographic distribution. North Africa, Middle East, Central Asia (
Natural hosts. Mammals, including cattle, horses, camels, sheep, goats, and humans, and birds (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Crimean-Congo hemorrhagic fever virus (
Hyalomma asiaticum Schülze & Schlottke, 1930
Hyalomma asiaticum kozlovi Olenev, 1931
Geographic distribution. Central Asia, Middle East (
Natural hosts. Mammals, including bovids, camels, rodents, lagomorphs, and hedgehogs, birds, and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia sibirica mongolitimonae, Coxiella burnetti (Q fever), and possibly Crimean-Congo Hemorrhagic Fever virus (
Hyalomma brevipunctatum Sharif, 1928
Geographic distribution. Southeast and Central Asia (
Natural hosts. Mammals, including bovids, deer, camels, horses, rodents, carnivores, shrews, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Hyalomma dromedarii Koch, 1844
Ixodes camelinus Fischer von Waldheim, 1823
Ixodes arenicola Eichwald, 1830
Ixodes trilineatus Lucas, 1844
Ixodes cinctus Lucas, 1844
Hyalomma yakimovi Olenev, 1931
Hyalomma yakimovi persiacum Olenev, 1931
Hyalomma delphy Schülze and Gossel in Schülze, 1936
Geographic distribution. Africa, Middle East, Central and Southeast Asia (
Natural hosts. Primarily camels, but also other mammals, birds, and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Crimean-Congo hemorrhagic fever virus (
Hyalomma excavatum Koch, 1844
Geographic distribution. North Africa, Mediterranean Europe, Middle East, Central Asia (
Natural hosts. Mammals, including bovids, camels, lagomorphs, rodents, hedgehogs, and humans, birds, and reptiles (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Hyalomma glabrum Delpy, 1949
Geographic distribution. South Africa (
Natural hosts. Immature stages on lagomorphs, carnivores, hyrax, rodents, and birds. Adults on bovids, occasionally carnivores. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Hyalomma hussaini Sharif, 1928
Geographic distribution. India, Pakistan, Myanmar (
Natural hosts. Immature stages on rodents and shrews. Adults on bovids, camels, pigs, carnivores, and horses. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Hyalomma impeltatum Schülze & Schlottke, 1930
Geographic distribution. Africa, Middle East, Central Asia (
Natural hosts. Mammals, including bovids, camels, horses, rhinoceroses, carnivores, and rodents, birds, and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Hyalmonna isaaci Sharif, 1928
Geographic distribution. Central and Southeast Asia (
Natural hosts. Immature stages on lagomorphs, deer, carnivores, and birds. Adults primarily on bovids. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Hyalomma lustanicum Koch, 1844
Geographic distribution. Mediterranean Europe and Africa (
Natural hosts. Mammals, including bovids and lagomorphs, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Hyalomma marginatum Koch, 1844
Geographic distribution. Europe, North Africa, Middle East, Central Asia (
Natural hosts. Several groups of mammals, including humans, and birds. Immature stages are primarily on small mammals and birds. Adults primarily on ungulates (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host: Skin.
Vectored pathogens. Crimean-Congo hemorrhagic fever virus (
Hyalomma rufipes Koch, 1844
Geographic distribution. Africa, Middle East (
Natural hosts. Several groups of mammals and birds. Immature stages are primarily on birds and lagomorphs. Adults are primarily on bovids. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Crimean-Congo hemorrhagic fever virus (
Hyalomma schulzei Olenev, 1931
Geographic distribution. Middle East, Central Asia (
Natural hosts. Immature stages primarily on rodents, hedgehogs, and lagomorphs. Adults primarily on camels, occasionally bovids. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Hyalomma scupense Schülze, 1919
Hyalomma detritum Schülze, 1919
Hyalomma detritum dardanicum Schülze & Schlottke, 1930
Hyalomma uralense Schülze & Schlottke, 1930
Hyalomma volgense Schülze & Schlottke, 1930
Geographic distribution. Europe, North Africa, Middle East, Central and East Asia (
Natural hosts. Bovids, camels, horses, pigs, deer, and humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Hyalomma truncatum Koch, 1844
Hyalomma transiens Schülze, 1919
Geographic distribution. Africa, Saudi Arabia, Yemen (
Natural hosts. Many groups of mammals, birds, and reptiles. Immature stages primarily on rodents and lagomorphs. Adults primarily on domestic and wild ungulates. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment
Site in human host. Skin
Vectored pathogens. Crimean-Congo hemorrhagic fever virus, Rickettsia connorii (boutonneuse fever), Coxiella burnetii (Q fever) (
Hyalomma turanicum Pomerantzev, 1946
Geographic distribution. North Africa, Middle East, Central and East Asia (
Natural hosts. Mammals, including bovids, lagomorphs, camels, pigs, horses, humans, and birds (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Genus Ixodes Latreille, 1795
Ixodes acuminatus Neumann, 1901
Geographic distribution. Europe, Middle East (
Natural hosts. Mammals, primarily rodents, but also other mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes acutitarsus (Karsch, 1880)
Ixodes gigas Warburton, 1910
Geographic distribution. Southeast Asia, Japan, India (
Natural hosts. Immature stages are typically on rodents; adults on ungulates. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes angustus Neumann, 1899
Geographic distribution. North America, Russia, Japan (
Natural hosts. Mammals, primarily rodents, but also other mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes apronophorus Schülze, 1924
Geographic distribution. Europe, Asia (
Natural hosts. Mammals, primarily rodents, but also other mammals, reptiles, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes asanumai Kitaoka, 1973
Geographic distribution. Japan (Okono 2010).
Natural hosts. Reptiles, rarely mammals and birds. Zoonotic on humans (Okono 2010).
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes australiensis Neumann, 1904
Geographic distribution. Australia (
Natural hosts. Marsupials, dogs, bovids. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes baergi Cooley & Kohls, 1942
Geographic distribution. North America (
Natural hosts. Passerine birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes banksi Bishopp, 1911
Geographic distribution. North America (
Natural hosts. Rodents, carnivores. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes boliviensis Neumann, 1904
Ixodes bicornis Neumann, 1906
Geographic distribution. Central and South America (
Natural hosts. Several groups of mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes brunneus Koch, 1844
Ixodes ricinus californicus Banks, 1908
Geographic distribution. Western Hemisphere (
Natural hosts. Birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes canisuga Johnston, 1849
Geographic distribution. Europe (
Natural hosts. Carnivores; immature stages occasionally on birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes cavipalpus Nuttall & Warburton, 1908
Ixodes rubicundus limbatus Neumann, 1908
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Ungulates, primarily cattle. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes columnae Takada & Fujita, 1992
Geographic distribution. Japan (
Natural hosts. Rodents, birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes confusus Roberts, 1960
Geographic distribution. Australia, Papua New Guinea (
Natural hosts. Ungulates, equids, marsupials. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes cookei Packard, 1869
Ixodes cruciarius Fitch, 1872
Geographic distribution. North America (
Natural hosts. Several groups of mammals, including humans, and birds (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Powassan virus lineage I (
Ixodes cornuatus Roberts, 1960
Geographic distribution. Australia (
Natural hosts. Mammals, primarily carnivores and rodents, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes crenulatus Koch, 1844
Geographic distribution. Europe, Asia (
Natural hosts. Mammals, primarily rodents, carnivores, lagomorphs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes cumulatimpunctatus Schülze, 1943
Ixodes pseudorasus Arthur & Burrow, 1957
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Several groups of mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes dentatus Marx in Neumann, 1899
Geographic distribution. North America (
Natural hosts. Immature stages on a variety of mammals and birds; adults on mammals, primarily lagomorphs and carnivores. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes eichhorni Nuttall, 1916
Geographic distribution. Southeast Asia, Australia, Pacific Islands (
Natural hosts. Birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes fecialis Warburton & Nuttall, 1909
Geographic distribution. Australia, Papua New Guinea (
Natural hosts. Marsupials. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment
Site in human host. Skin
Vectored pathogens. None
Ixodes festai Rondelli, 1926
Geographic distribution. Southern Europe, northern Africa (
Natural hosts. Birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes frontalis (Panzer, 1798)
Geographic distribution. Europe, Middle East (
Natural hosts. Birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes gibbosus Nuttall, 1916
Geographic distribution. Southern, eastern Europe, Middle East (
Natural hosts. Ungulates, primarily bovids, rarely birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes granulatus Supino, 1897
Geographic distribution. Southeast Asia (
Natural hosts. Mammals, birds, reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes hexagonus Leach, 1815
Geographic distribution. Europe (
Natural hosts. Mammals, primarily hedgehogs, also birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes holocyclus Neumann, 1899
Geographic distribution. East coastal Australia (
Natural hosts. Marsupials, primarily bandicoots, also livestock, cats, dogs, and humans, and birds (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia australis (Queensland tick typhus); also implicated in tick paralysis (
Ixodes kaschmiricus Pomerantsev, 1948
Geographic distribution. Central and East Asia (
Natural hosts. Mammals, primarily bovids, carnivores, rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes kazakstani Olenev & Sorokoumov, 1934
Geographic distribution. Central Asia (
Natural hosts. Several mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes kingi Bishopp, 1911
Geographic distribution. North America (
Natural hosts. Mammals, including carnivores, rodents, lagomorphs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes kohlsi Arthur, 1955
Geographic distribution. Australia (
Natural hosts. Birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes laguri Olenev, 1929
Geographic distribution. Central and Eastern Europe, Asia (
Natural hosts. Mammals, primarily rodents, lagomorphs, shrews, hedgehogs, carnivores. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes marxi Banks, 1908
Geographic distribution. North America (
Natural hosts. Mammals, primarily rodents; also birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Powassan virus lineage I (
Ixodes monospinosus Saito, 1968
Geographic distribution. Japan (
Natural hosts. Mammals, including bovids, deer, rodents, carnivores, shrews. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes muniensis Arthur & Burrow, 1957
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Mammals, including bovids, pigs, giraffes, hyrax, carnivores, rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes muris Bishopp & Smith, 1937
Geographic distribution. North America (
Natural hosts. Mammals, primarily rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes myrmecobii Roberts, 1962
Geographic distribution. Australia (
Natural hosts. Marsupials, rarely other mammals, birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes nipponensis Kitaoka & Saito, 1967
Geographic distribution. Southeast Asia, Japan, Russia (
Natural hosts. Mammals, primarily carnivores, bovids, deer, lagomorphs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes ovatus Neumann, 1899
Ixodes japonensis Neumann, 1904
Ixodes frequens Ogura & Takada, 1927
Ixodes carinatus Kishida, 1930
Ixodes lindbergi Santos Dias, 1959
Geographic distribution. Central, Eastern, Southeastern Asia (
Natural hosts. Mammals, including rodents, lagomorphs, carnivores, shrews, humans, and birds (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin, ear (
Vectored pathogens. Rickettsia japonica (Japanese spotted fever) (
Ixodes pacificus Cooley & Kohls, 1943
Ixodes californicus Banks, 1904
Geographic distribution. Western North America (
Natural hosts. Small mammals, birds, and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Borrelia burgdorferi (Lyme disease), B. miyamotoi (tick-borne relapsing fever), Anaplasma phagocytophilum (human granulocytic anaplasmosis) (
Ixodes pararicinus Keirans & Clifford in Keirans et al. 1985
Geographic distribution. Argentina, Colombia, Peru (
Natural hosts. Immature stages are primarily on small mammals and birds. Adults are on ungulates, including bovids, peccaries, and deer. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes pavlovskyi Pomerantzev, 1946
Geographic distribution. Central Asia, Russia, Japan (
Natural hosts. Birds and mammals, including rodents, lagomorphs, carnivores, hedgehogs, shrews, and humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes persulcatus (Schülze, 1930)
Geographic distribution. Europe, Northern Asia (
Natural hosts. Mammals, including dogs, deer, rodents, lagomorphs, and humans, and ground-nesting birds (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin, ear (
Vectored pathogens. Borrelia miyamotoi (tick-borne relapsing fever), B. garinii, tick-borne encephalitis viruses (TBE) (
Ixodes petauristae Warburton, 1933
Geographic distribution. India, Sri Lanka (
Natural hosts. Mammals, primarily rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes pilosus Koch, 1844
Geographic distribution. Southern Africa (
Natural hosts. Mammals, primarily ungulates. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes rageaui Arthur, 1958
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Non-human primates. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes rasus Neumann, 1899
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Mammals, including ungulates, carnivores, rodents, and hyrax, and birds, Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes redikorzevi Olenev, 1927
Ixodes theodori Warburton, 1927
Geographic distribution. Europe, North Africa, Middle East, Asia (
Natural hosts. Mammals, including rodents, hedgehogs, lagomorphs, and carnivores, birds, and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes ricinus (Linnaeus, 1758)
Acarus reduvius Linnaeus, 1758
Geographic distribution. Europe, North Africa, Middle East, northern Asia (
Natural hosts. Many mammals, including humans, and birds. Immature stages are typically on small mammals, reptiles, and birds. Adults are on ungulates and dogs (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Borrelia burgdorferi sensu lato (Lyme disease), B. miyamotoi (tick-borne relapsing fever), Coxiella burnetii (Q fever), Babesia divergens (babesiosis), tick-borne encephalitis viruses (TBE), louping ill virus (
Ixodes rubicundus Neumann, 1904
Geographic distribution. South Africa (
Natural hosts. Mammals, including ungulates, rodents, lagomorphs, and carnivores. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes rugosus Bishopp, 1911
Geographic distribution. North America (
Natural hosts. Mammals, primarily carnivores, but also opossums and rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes scapularis Say, 1821
Ixodes ozarkus Cooley, 1944
Ixodes dammini Spielman et al., 1979
Geographic distribution. Eastern and Midwestern North America (
Natural hosts. Immature stages are primarily on rodents and other small mammals, reptiles, small birds. Adults are on ungulates (primarily deer) and dogs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Borrelia burgdorferi sensu lato and B. mayonii (Lyme disease), B. miyamotoi (tick-borne relapsing fever), Babesia microti (babesiosis), Anaplasma phagotocytophilum (human granulocytic anaplasmosis), deer tick virus (Powassan virus lineage II) (
Ixodes schillingsi Neumann, 1901
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Non-human primates. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes sculptus Neumann, 1904
Geographic distribution. Central Asia, Russia, Japan (
Natural hosts. Primarily rodents and lagomorphs, rarely ungulates and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes sinensis Teng, 1977
Geographic distribution. China (
Natural hosts. Mammals, including ungulates, rodents, and lagomorphs, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes soricis Gregson, 1942
Geographic distribution. North America (
Natural hosts. Shrews and rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes spinicoxalis Neumann, 1899
Geographic distribution. Southeast Asia (
Natural hosts. Mammals, tree shrews, rodents, and carnivores, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes spinipalpis Hawden et Nuttall in Nutall, 1916
Geographic distribution. North America (
Natural hosts. Mammals, primarily rodents, but also lagomorphs and carnivores, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes tancitarius Cooley & Kohls, 1942
Geographic distribution. Mexico (
Natural hosts. Rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Notes. The single human record from Mexico is considered tentative (
Ixodes tanuki Saito, 1964
Geographic distribution. Southeast Asia, Japan (
Natural hosts. Mammals, including carnivores, rodents, and ungulates. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes tasmani Neumann, 1899
Geographic distribution. Southeast Asia, Japan (
Natural hosts. Mammals, including marsupials, carnivores, and rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes texanus Banks, 1909
Geographic distribution. North America (
Natural hosts. Mammals, primarily carnivores. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes trainguliceps Birula, 1895
Geographic distribution. Europe, northwestern Asia (
Natural hosts. Mammals, primarily shrews, but also rodents and carnivores; birds, lizards. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes turdus Nakatsudi, 1942
Geographic distribution. Southeast Asia, Japan (
Natural hosts. Birds, rarely rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes uriae White, 1852
Hyalomma puta Pickard-Cambridge, 1876
Geographic distribution. North America, Europe, Russia, southern Africa, Australia (
Natural hosts. Predominately birds, but also mammals, including carnivores, rodents, and humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes vanidicus Schülze, 1943
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Mammals, including carnivores and elephant shrews. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes ventalloi Gil Collado, 1936
Geographic distribution. Europe, northern Africa (
Natural hosts. Mammals, including carnivores, rodents, and lagomorphs; birds, and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes vespertilionis Koch, 1844
Geographic distribution. Europe, Africa, Asia (
Natural hosts. Bats. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Ixodes woodi Bishopp, 1911
Geographic distribution. North America (
Natural hosts. Mammals, primarily rodents, also carnivores. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Genus Nosomma Schülze, 1919
Nosomma monstrosum (Nuttall & Warburton, 1908)
Geographic distribution. Central and Southeast Asia (
Natural hosts. Immature stage primarily on rodents and shrews. Adults primarily on bovids, deer, pics, horses, and carnivores. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Genus Rhipicephalus Koch, 1844
Rhipicephalus annulatus (Say, 1821)
Rhipicephalus calcaratus Birula, 1895
Geographic distribution. North America, Africa, Europe, Middle East, Central Asia (
Natural hosts. Primarily cattle, but also other mammals, birds, and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus appendiculatus Neumann, 1901
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Mammals, including cattle, buffalo, antelope, warthogs, equids, lagomorphs, and dogs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus armatus Pocock, 1900
Geographic distribution. East Africa (
Natural hosts. Carnivores, bovids, and lagomorphs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus aurantiacus Neumann, 1907
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Bovids, pigs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus australis Fuller, 1899.
Geographic distribution. Southeast Asia, Australia, Pacific Islands (
Natural hosts. Mammals, primarily bovids. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus bequaerti Zumpt, 1950
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Bovids, pigs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus bursa Canestrini er Fanzago, 1878
Geographic distribution. Southern Europe, North Africa, Middle East, Central and East Asia (
Natural hosts. Mammals, primarily bovids, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus carnivoralis Walker, 1966
Geographic distribution. East Africa (
Natural hosts. Primarily felids, also other mammals including bovids and hyrax. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus complanatus Neumann, 1911
Geographic distribution. West Africa (
Natural hosts. Pigs, bovids, carnivores, and rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus compositus Neumann, 1897
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Immature stages primarily on rodents. Adults primarily on bovids, pigs, carnivores, horses, rhinoceroses. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus decoloratus Koch, 1844
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Primarily bovids, also other mammals, birds, and tortoises. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus distinctus Bedford, 1932
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Primarily hyrax, also lagomorphs, carnivores, rodents, and elephant shrews. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus evertsi Neumann, 1897
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Several groups of mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus follis Dönitz, 1910
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Mammals, including bovids, pigs, carnivores, horses, rhinoceroses, hyrax, and rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus fulvus Neumann, 1913
Geographic distribution. Central and northern Africa (
Natural hosts. Bovids, camels, rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus gertrudae Feldman-Muhsam, 1960
Geographic distribution. Southern Africa (
Natural hosts. Several groups of mammals, birds, and reptiles. Immature stages primarily on rodents. Adults primarily on bovids. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus glabroscutatus Du Toit, 1941
Geographic distribution. South Africa (
Natural hosts. Immature stages primarily on carnivores, rodents, birds. Adults primarily on lagomorphs, horses, and hyrax. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus guilhoni Morel & Vassiliades, 1963
Geographic distribution. Africa (
Natural hosts. Several groups of mammals and birds. Immature stages primarily on rodents, lagomorphs. Adults primarily on bovids. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus haemaphysaloides Supino, 1897
Geographic distribution. Central and Southeast Asia (
Natural hosts. Mammals, including carnivores, rodents, bovids, and shrews; birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin, ear (
Vectored pathogens. None.
Rhipicephalus humeralis Tonelli-Rondelli, 1926
Geographic distribution. East Africa (
Natural hosts. Various groups of mammals. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus hurti Wilson, 1954
Geographic distribution. East Africa (
Natural hosts. Mammals, including bovids, pigs, carnivores, rhinoceroses, and rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus jeanneli Neumann, 1913
Geographic distribution. East Africa (
Natural hosts. Mammals, including bovids, pigs, horses, rhinoceroses, and carnivores, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus kochi Dönitz, 1905
Rhipicephalus neavi Warburton, 1912
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Mammals, including bovids, elephant shrews, lagomorphs, and pigs; birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus longus Neumann, 1907
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Mammals, primarily bovids and pigs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus lunulatus Neumann, 1907
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Mammals, including bovids, lagomorphs, elephant shrews, and rodents; birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus maculatus Neumann, 1901
Geographic distribution. Southern and East Africa (
Natural hosts. Mammals, including bovids, rhinoceroses, carnivores, horses, and elephants; rarely reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus microplus (Canestrini, 1888)
Geographic distribution. Circumtropical (
Natural hosts. Several groups of mammals, especially livestock; birds and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus muehlensi Zumpt, 1943
Geographic distribution. Africa (
Natural hosts. Several groups of mammals. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus pilans Schülze, 1935
Geographic distribution. East Timor, Indonesia, Philippines (
Natural hosts. Several groups of mammals. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus planus Neumann, 1907
Rhipicephalus reichenowi Zumpt, 1943
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Several groups of mammals. Immature stages primarily on rodents and lagomorphs. Adults primarily on bovids and pigs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus praetextatus Gerstäcker, 1873
Geographic distribution. Africa, Yemen (
Natural hosts. Several groups of mammals and birds. Immature stages primarily on rodents. Adults primarily on bovids. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus parvus Dönitz, 1910
Geographic distribution. East Africa (
Natural hosts. Several groups of mammals, birds, and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus pulchellus (Gerstäcker, 1873)
Geographic distribution. East Africa (
Natural hosts. Several groups of mammals, especially bovids, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus pumilio Schülze, 1935
Geographic distribution. Central and East Asia (
Natural hosts. Several groups of mammals, including hedgehogs, rodents, and lagomorphs, and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus pusillus Gil Collado, 1936
Geographic distribution. Mediterranean Europe and Africa(
Natural hosts. Several groups of mammals and birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus rossicus Yakimov et Kohl-Yakimova, 1911
Geographic distribution. Eastern Europe, Asia (
Natural hosts. Several groups of mammals, birds, and reptiles. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus sanguineus (Latreille, 1806)
Geographic distribution. Worldwide (
Natural hosts. Several groups of mammals, especially dogs. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia rickettsii (Rocky Mountain spotted fever), R. conorii (boutonneuse fever) (
Rhipicephalus schulzei Olenev, 1929
Geographic distribution. Central and East Asia (
Natural hosts. Mammals, including rodents, lagomorphs, and carnivores; birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus senegalensis Koch, 1844
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Several groups of mammals and birds. Immature stages primarily on carnivores, elephant shrews, and rodents. Adults primarily on bovids, especially domestic cattle, and other mammals. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus simus Koch, 1844
Geographic distribution. Southern and East Africa (
Natural hosts. Several groups of mammals. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus sulcatus Neumann, 1908
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Several groups of mammals. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus supertritus Neumann, 1907
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Several groups of mammals, especially bovids. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus turanicus Pomerantzev, 1936
Geographic distribution. Hard to define but generally considered broadly distributed in Africa and Asia (
Natural hosts. Several groups of mammals, including humans, birds, and reptiles (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Rickettsia conorii (boutonneuse fever) (
Rhipicephalus warburtoni Walker et Horak in Walker et al., 2000
Geographic distribution. South Africa (
Natural hosts. Mammals, including bovids, elephant shrews, lagomorphs, carnivores, horses, and rodents; birds. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus zambeziensis Walker et al., 1981
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Many groups of mammals and birds. Immature stages primarily on lagomorphs. Adults primarily on bovids. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus ziemanni Neumann, 1904
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Mammals, primarily carnivores and rodents. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Rhipicephalus zumpti Santos Dias, 1950
Geographic distribution. Southern and Eastern Africa (
Natural hosts. Several groups of mammals. Zoonotic on humans (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
●●●●●●●●●●●●● Argasidae Koch, 1844
Genus Argas Latreille, 1795
Argas monolakensis
Geographic distribution. Mono Lake, California, USA (
Natural hosts. Birds, primarily California gulls (Larus californicus) (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Argas persicus (Oken, 1818)
Geographic distribution. Worldwide (
Natural hosts. Birds. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Kyasanur Forest disease virus (
Genus Ornithodoros Koch, 1844
Ornithodoros erraticus Lucas, 1849
Geographic distribution. Mediterranean Region (
Natural hosts. Many mammals, including pigs, rodents, insectivores, canids, mustelids, bats. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Borrelia hispanica (tick-borne relapsing fever) (
Ornithodoros graingeri Heisch & Guggisberg, 1953
Geographic distribution. Kenya (
Natural hosts. Rodents. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Borrelia graingeri (tick-borne relapsing fever) (
Ornithodoros hermsi Wheeler, 1935
Geographic distribution. Western North America (
Natural hosts. Rodents. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Borrelia hermsii (tick-borne relapsing fever) (
Ornithodoros marocanus Velu, 1919
Geographic distribution. Mediterranean Region (
Natural hosts. Many mammals, including rodents, insectivores, canids, mustelids, bats. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Borrelia hispanica (tick-borne relapsing fever) (
Ornithodoros moubata Murray, 1877
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Pigs, poultry. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Borrelia duttoni (tick-borne relapsing fever) (
Ornithodoros parkeri Cooley, 1936
Geographic distribution. Western North America (
Natural hosts. Rodents, horses. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Borrelia parkeri (tick-borne relapsing fever) (
Ornithodoros rudis Karsch, 1880
Ornithodoros venezuelensis Brumpt, 1921
Geographic distribution. Panama and South America (Faccini-Martínez Á and Botero-García 2016).
Natural hosts. Birds, primarily poultry. Zoonotic on humans as incidental hosts (Faccini-Martínez Á and Botero-García 2016;
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Borrelia venezuelensis (tick-borne relapsing fever) (Faccini-Martínez Á and Botero-García 2016;
Ornithodoros sonrai Sautet & Witkowski, 1944
Geographic distribution. Western and northern Africa (
Natural hosts. Rodents, insectivores. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Borrelia crocidurae (tick-borne relapsing fever) (
Ornithodoros talajae (Guérin-Méneville, 1849)
Geographic distribution. Southern United States, Central and South America (Cooley 1945; Faccini-Martínez Á and Botero-García 2016).
Natural hosts. Many mammals. Zoonotic on humans as incidental hosts (Cooley 1945;
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Borrellia mazzottii (tick-borne relapsing fever) (
Ornithodoros tholozani Laboulbène & Mégnin, 1882
Geographic distribution. Middle East, North Africa, Central Asia, India (
Natural hosts. Rodents, insectivores. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Borrelia persica (tick-borne relapsing fever) (
Ornithodoros turicata (Dugès, 1876)
Geographic distribution. Western and Midwestern North America, Mexico (Cooley 1945).
Natural hosts. Rodents, dogs. Zoonotic on humans as incidental hosts (Cooley 1945;
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Borrelia turicatae (tick-borne relapsing fever) (
Ornithodoros verrucosus Olenev et al., 1934
Geographic distribution. Eastern Europe (
Natural hosts. Rodents. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to larval, nymph, or adult ticks in the environment.
Site in human host. Skin.
Vectored pathogens. Borrelia caucasica (tick-borne relapsing fever) (
Genus Otobius Banks, 1912
Otobius megnini (Dugès, 1884)
Geographic distribution. Nearly worldwide wherever livestock are raised (Cooley 1945).
Natural hosts. Cattle, sheep, goats, deer, other ruminants, carnivores, rabbits. Zoonotic on humans as incidental hosts (Cooley 1945).
Route of infection. Exposure to larval or nymph ticks in the environment.
Site in human host. Ears (Cooley 1945;
Vectored pathogens. None.
●●●●●●●●●●●● Mesostigmata Canestrini, 1891
●●●●●●●●●●●●● Dermanyssoidea Kolenati, 1859
●●●●●●●●●●●●●● Dermanyssidae Kolenati, 1859
Genus Dermanyssus Dugès, 1834
Dermanyssus gallinae (DeGeer, 1778)
Geographic distribution. Worldwide (
Natural hosts. Birds. Zoonotic on humans as incidental hosts (
Route of infection. Contact with infected birds (
Site in human host. Skin, ear (
Vectored pathogens. None.
Genus Liponyssoides Hirst, 1913
Liponyssoides sanguineus (Hirst, 1914)
Geographic distribution. Worldwide (
Natural hosts. Rodents. Zoonotic on humans as incidental hosts (
Route of infection. Contact with and living among infected rodents (
Site in human host. Skin (
Vectored organism. Rickettsia akari (rickettsialpox) (
●●●●●●●●●●●●●● Laelapidae Berlese, 1892
Genus Laelaps Koch, 1836
Laelaps echidnina Berlese, 1887
Geographic distribution. Worldwide (
Natural hosts. Rodents, primarily rats (Rattus). Zoonotic on humans as incidental hosts (
Route of infection. Contact with and living among infected rodents (
Site in human host. Skin (
Vectored pathogens. None.
●●●●●●●●●●●●●● Macronyssidae Oudemans, 1936
Genus Ophionyssus Mégnin, 1884
Ophionyssus natricis (Gervais, 1844)
Geographic distribution. Worldwide (
Natural hosts. Reptiles, primarily snakes, also lizards. Zoonotic on humans as incidental hosts (
Route of infection. Contact with infected reptiles (
Site in human host. Skin (
Vectored pathogens. None.
Genus Ornithonyssus Sambon, 1928
Ornithonysus bacoti (Hirst, 1913)
Geographic distribution. Tropics and subtropics worldwide (
Natural hosts. Rodents, primarily rats (Rattus). Zoonotic on humans as incidental hosts (
Route of infection. Contact with and living among infected rodents (
Site in human host. Skin (
Vectored pathogens. None.
Ornithonyssus bursa (Berlese, 1888)
Geographic distribution. Tropics and subtropics worldwide (
Natural hosts. Birds. Zoonotic on humans as incidental hosts (
Route of infection. Contact with and living among infected birds (
Site in human host. Skin (
Vectored pathogens. None.
Ornithonyssus sylviarum (Canestrini & Fanzago, 1877)
Geographic distribution. Worldwide (
Natural hosts. Birds. Zoonotic on humans as incidental hosts (
Route of infection. Contact with and living among infected birds (
Site in human host. Skin (
Vectored pathogens. None.
●●●●●●● Mandibulata Snodgrass, 1938
●●●●●●●● Pancrustacea Zrzavý & Štys, 1997
Tetraconata Dohle, 2001
●●●●●●●●● Crustacea Brünnich, 1772
●●●●●●●●●● Maxillopoda Dahl, 1956
●●●●●●●●●●● Pentastomida Diesing, 1836
●●●●●●●●●●● Porocephalidae Sambon, 1922
Genus Armillifer Sambon, 1922
Armillifer agkistrodontis Self & Kuntz, 1966
Geographic distribution. China (
Natural hosts. Intermediate hosts are rodents. Definitive hosts are snakes. Zoonotic in humans as dead-end hosts (
Route of infection. Ingestion of infected intermediate or reservoir host (
Site in human host. Disseminated infection, including the mesenteries, peritoneum, lungs (
Armillifer armillatus Wyman, 1845
Geographic distribution. Central and western Africa (Christoffersen and Assis 2013;
Natural hosts. Intermediate hosts are various mammals. Definitive hosts are pythons. Zoonotic in humans as dead-end hosts (Christoffersen and Assis 2013;
Route of infection. Ingestion of infected intermediate or reservoir host (
Site in human host. Disseminated infection, including the mesenteries, peritoneum, lungs, brain, eye. (
Armillifer grandis Hett, 1915
Geographic distribution. Central and western Africa (Christoffersen and Assis 2013;
Natural hosts. Intermediate hosts are rodents. Definitive hosts are viperid snakes. Zoonotic in humans as dead-end hosts (Christoffersen and Assis 2013;
Route of infection. Ingestion of infected intermediate or reservoir host (
Site in human host. Disseminated infection, including the mesenteries, peritoneum, lungs, brain, and eye (
Armillifer moniliformis (Diesing, 1835)
Geographic distribution. Southeast Asia (Christoffersen and Assis 2013;
Natural hosts. Intermediate hosts are various mammals. Definitive hosts are snakes. Zoonotic in humans as dead-end hosts (Christoffersen and Assis 2013;
Route of infection. Ingestion of infected intermediate or reservoir host (
Site in human host. Disseminated infection, including the mesenteries, peritoneum, lungs, liver (
Genus Porocephalus Humboldt, 1811
Porocephalus crotali (Humboldt, 1808)
Geographic distribution. New World (
Natural hosts. Intermediate hosts are small mammals, including rodents, monkeys. Definitive hosts are snakes, primarily rattlesnakes (Crotalus). Zoonotic in humans as dead-end hosts (
Route of infection. Ingestion of infected intermediate or reservoir host (
Site in human host. Disseminated infection, including the mesenteries, peritoneum, lungs (
Porocephalus subuliferum (Leuckart, 1860)
Geographic distribution. Africa (
Natural hosts. Intermediate and definitive hosts are snakes. Zoonotic in humans as dead-end hosts (
Route of infection. Ingestion of infected intermediate host (
Site in human host. Viscera (
Porocephalus taiwana Qui et al., 2005
Geographic distribution. Southeast Asia (
Natural hosts. Intermediate hosts are unknown. Definitive hosts are snakes. Zoonotic in humans as dead-end hosts (Christoffersen and Assis 2013).
Route of infection. Ingestion of infected intermediate or reservoir host (
Site in human host. Disseminated disease, including greater omentum, small intestine, liver, lungs (
●●●●●●●●●●● Linguatulidae Haldeman, 1851
Genus Linguatula Fröhlich, 1789
Linguatula serrata Fröhlich, 1789
Geographic distribution. Worldwide (Christoffersen and Assis 2013).
Natural hosts. Intermediate hosts are sheep, bovids, rodents. Definitive hosts are felids and canids. Zoonotic in humans as dead-end hosts (Christoffersen and Assis 2013).
Route of infection. Ingestion of infected intermediate or reservoir host (
Site in human host. Disseminated infection, including the mesenteries, peritoneum, lungs, eyes (
●●●●●●●●●●● Raillietiellidae Sambon, 1922
Genus Raillietiella Sambon in Vaney & Sambon, 1910
Geographic distribution. Worldwide (Christoffersen and Assis 2013).
Natural hosts. Intermediate hosts are insects. Definitive hosts are reptiles and amphibians. Zoonotic in humans as dead-end hosts (Christoffersen and Assis 2013).
Route of infection. Ingestion of infected intermediate or reservoir host (
Site in human host. Disseminated infection, including the mesenteries, peritoneum, lungs (
Notes. Raillietiella isolates from human hosts have not been characterized at the species level. Cases of R. hemidactyli Hett, 1934 and R. gehyrae Bovien, 1927 from Vietnam were not confirmed morphologically (
●●●●●●●●●●● Sebekidae Sambon, 1922
Genus Leiperia Sambon, 1922
Leiperia cincinallis Sambon, in Vaney and Sambon 1910
Geographic distribution. Africa (Christoffersen and Assis 2013).
Natural hosts. Intermediate hosts are freshwater fish. Definitive hosts are crocodiles and turtles. Zoonotic in humans as dead-end hosts (Christoffersen and Assis 2013).
Route of infection. Presumably ngestion of infected intermediate or paratenic host.
Site in human host. Intestine (?) (
Notes. Leiperia cincinallis has been reported from the stool of a European woman in Zaire (
Genus Sebekia Sambon, 1922
Geographic distribution. Australia, South America, Southeast Asia, southern Africa (Christoffersen and Assis 2013).
Natural hosts. Intermediate hosts are freshwater fish. Definitive hosts are crocodiles and snakes (Christoffersen and Assis 2013).
Route of infection. Presumably by ingestion of infected intermediate or paratenic host.
Site in human host. Skin (
Notes. A single human case of Sebekia, manifesting as dermatitis in a woman in Costa Rica (
●●●●●●●●● Hexapoda Latreille, 1825
●●●●●●●●●● Insecta Linnaeus, 1758
●●●●●●●●●●● Hemiptera Linnaeus, 1758
●●●●●●●●●●●● Reduviidae Latreille, 1807
Genus Meccus Stål, 1859
Meccus pallidipennis (Stål, 1872)
Geographic distribution. Mexico (
Natural hosts. Various mammals. Zoonotic on humans (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. Trypanosoma cruzi (Chagas Disease, American trypanosomiasis) (
Genus Panstrongylus Berg, 1879
Panstrongylus geniculatus (Latreille, 1811)
Geographic distribution. Central and South America (
Natural hosts. Armadillos. Zoonotic on humans (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Panstrongylus megistus (Burmeister, 1835)
Geographic distribution. Argentina, Bolivia, Brazil, Paraguay, Uruguay (
Natural hosts. Various mammals. Zoonotic on humans (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. Trypanosoma cruzi (Chagas disease, American trypanosomiasis) (
Genus Paratriatoma Barber, 1938
Paratriatoma hirsuta Barber, 1938
Geographic distribution. Southwestern USA, Mexico (
Natural hosts. Rodents. Zoonotic on humans (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Genus Rhodnius Stål, 1859
Rhodnius prolixus Stål, 1859
Geographic distribution. Central and South America (
Natural hosts. Various mammals. Zoonotic on humans (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. Trypanosoma cruzi (Chagas disease, American trypanosomiasis) (
Genus Triatoma Laporte de Castelnau, 1832
Triatoma brasiliensis Neiva, 1911
Geographic distribution. Brazil (
Natural hosts. Various mammals. Zoonotic on humans (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. Trypanosoma cruzi (Chagas disease, American trypanosomiasis) (
Triatoma dimidiata (Latrielle, 1811)
Geographic distribution. Central and South America (
Natural hosts. Various mammals. Zoonotic on humans (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. Trypanosoma cruzi (Chagas disease, American trypanosomiasis) (
Triatoma gerstaeckeri (Stål, 1859)
Geographic distribution. Southwestern USA, Mexico (
Natural hosts. Various mammals. Zoonotic on humans (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. None (T. gerstaeckeri has been found to be naturally infected with Trypanosoma cruzi but its role as a natural vector for human disease is not fully understood) (
Triatoma infestans (Klug in Meyen, 1834)
Geographic distribution. South America (
Natural hosts. Various mammals. Zoonotic on humans (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. Trypanosoma cruzi (Chagas disease, American trypanosomiasis) (
Triatoma lectularia (Stål, 1859)
Geographic distribution. Southern and southeastern USA, Mexico (
Natural hosts. Various mammals. Zoonotic on humans (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. None (T. lectularia has been found to be naturally infected with Trypanosoma cruzi but its role as a natural vector for human disease is not fully understood) (
Triatoma protracta (Uhler, 1894)
Geographic distribution. Southwestern USA, Mexico (
Natural hosts. Woodrats (Neotoma). Zoonotic on humans (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. None (T. protracta has been found to be naturally infected with Trypanosoma cruzi but its role as a natural vector for human disease is not fully understood) (
Triatoma pseudomaculata Correa & Espínola, 1964
Geographic distribution. Brazil (
Natural hosts. Various mammals. Zoonotic on humans (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. Trypanosoma cruzi (Chagas disease, American trypanosomiasis) (
Triatoma recurva (Stål, 1868)
Geographic distribution. Southwestern USA, Mexico (
Natural hosts. Rodents. Zoonotic on humans (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. None (T. recurva has been found to be naturally infected with Trypanosoma cruzi but its role as a natural vector for human disease is not fully understood) (
Triatoma rubida (Uhler, 1894)
Geographic distribution. Southwestern USA, Central America (
Natural hosts. Rodents. Zoonotic on humans (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. None (T. rubida has been found to be naturally infected with Trypanosoma cruzi but its role as a natural vector for human disease is not fully understood) (
Triatoma rubrofasciata (De Geer, 1773)
Geographic distribution. Eastern North America, Southeast Asia, Pacific Islands (
Natural hosts. Rodents. Zoonotic on humans (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. None; implicated in anaphylactic shock from bites (
Triatoma sanguisuga (LeConte, 1855)
Geographic distribution. Eastern United States (
Natural hosts. Several groups of mammals, birds, reptiles, and amphibians. Zoonotic on humans (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Triatoma sordida (Stål, 1859)
Geographic distribution. South America (
Natural hosts. Various mammals. Zoonotic on humans (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin
Vectored pathogens. Trypanosoma cruzi (Chagas Disease, American trypanosomiasis) (
●●●●●●●●●●●● Cimicidae Latreille, 1802
Genus Cimex Linnaeus, 1758
Cimex adjunctus Barber, 1939
Geographic distribution. Eastern North America (Goddard 2012).
Natural hosts. Bats. Zoonotic on humans as incidental hosts (Goddard 2012).
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Cimex hemipterus (Fabricius, 1802)
Geographic distribution. Circumtropical (
Natural hosts. Humans (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Cimex lectularius Linnaeus, 1758
Geographic distribution. Worldwide (
Natural hosts. Humans (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Cimex pilosellus (Horváth, 1910)
Geographic distribution. Western North America (Goddard 2012).
Natural hosts. Bats. Zoonotic on humans as incidental hosts (Goddard 2012).
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Cimex pipistrelli Jenyns, 1839
Geographic distribution. Europe and Central Asia (Goddard 2012).
Natural hosts. Bats. Zoonotic on humans as incidental hosts (Goddard 2012).
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Genus Leptocimex Roubaud, 1913
Leptocimex boueti (Brumpt, 1910)
Geographic distribution. Africa (
Natural hosts. Bats. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Genus Haematosiphon Champion, 1900
Haematosiphon inodora (Dugès, 1892)
Geographic distribution. North and Central America (
Natural hosts. Birds, primarily poultry. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Genus Hesperocimex List, 1925
Hesperocimex coloradensis List, 1925
Geographic distribution. North and Central America (
Natural hosts. Birds. Zoonotic on humans as incidental hosts (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. None.
Genus Oeciacus Stål, 1873
Oeciacus vicarius Horváth, 1912
Geographic distribution. North America (
Natural hosts. Birds, primarily chimney swifts (Chaetura). Zoonotic on humans as incidental hosts (
Route of infection. Exposure to nymphs and adults in the environment.
Site in human host. Skin.
Vectored pathogens. None.
●●●●●●●●●●● Psocodea Hennig, 1966
Anoplura Leach, 1815
Phthiraptera Haeckel, 1896
●●●●●●●●●●●● Pediculidae Leach, 1817
Genus Pediculus Linnaeus, 1758
Pediculus humanus capitis De Geer, 1778
Geographic distribution. Worldwide (
Natural hosts. Humans (
Route of infection. Direct person-to-person contact, contaminated fomites (
Site in human host. Hair shafts, commonly on the scalp (
Vectored pathogens. None.
Pediculus humanus humanus Linnaeus, 1758
Pediculus corporis De Geer, 1778
Geographic distribution. Worldwide (
Natural hosts. Humans (
Route of infection. Direct person-to-person contact, contaminated fomites (
Site in human host. Skin; P. h. humanus primarily lives off the human host and only migrates over to feed (
Vectored pathogens. Rickettsia prowazekii (epidemic typhus), Bartonella quintana (trench fever), Borrelia recurrentis (louse-borne relapsing fever) (
●●●●●●●●●●●● Pthiridae Ewing, 1929
Genus Pthirus Leach, 1815
Phthirus, misspelling
Pthirus pubis (Linnaeus, 1758)
Geographic distribution. Worldwide (
Natural hosts. Humans (
Route of infection. Direct person-to-person contact (
Site in human host. Hair shafts, usually coarse hair (pubic hair, eyebrows, eye lashes, facial hair) (
Vectored pathogens. None.
●●●●●●●●●●● Coleoptera Linnaeus, 1758
●●●●●●●●●●●● Ptinidae Latreille, 1802
Genus Stegobium Motschulsky, 1860
Stegobium paniceum (Linnaeus, 1758)
Geographic distribution. Worldwide (
Natural hosts. None; causes facultative canthariasis (infestation with beetles) in humans (
Route of infection. Contamination from the environment (
Site in human host. Skin (
Vectored pathogens. None.
Notes. This species was reported from the skin of a patient with lupus after treatment for facultative myiasis caused by Lucilia sericata (
Genus Trogoderma Dejean, 1821
Geographic distribution. Worldwide (
Natural hosts. None; causes facultative canthariasis in humans (
Route of infection. Contamination from the environment (
Site in human host. Skin (
Vectored pathogens. None
Notes. A member of this genus was reported from the skin of a patient with lupus after treatment for facultative myiasis caused by Lucilia sericata (
●●●●●●●●●●●● Tenebrionidae Latreille, 1802
Genus Tenebrio Linnaeus, 1758
Tenebrio molitor Linnaeus, 1758
Geographic distribution. Worldwide (
Natural hosts. None; causes facultative canthariasis in humans (Rodriguez-Morales 2018).
Route of infection. Contamination from the environment (Rodriguez-Morales 2018).
Site in human host. Skin ulcer (Rodriguez-Morales 2018).
Vectored pathogens. None.
Notes. Tenebrio molitor is a cosmopolitan pest of stored grains and other foodstuffs. A larva of T. molitor was discovered in a skin ulcer of an AIDS patient in rural Colombia (Rodriguez-Morales 2018). This case represents facultative canthariasis. Previous reports of T. molitor from the human intestinal tract (
●●●●●●●●●●● Siphonaptera Latreille, 1824
●●●●●●●●●●●● Heteropsyllidae Baker, 1904
Genus Tunga Jarocki, 1838
Tunga penetrans (Linnaeus, 1758)
Geographic distribution. Central and South America, Caribbean, Africa, Madagascar, Central Asia (
Natural hosts. Many mammals. Zoonotic on humans (
Route of infection. Contact with contaminated soil (e.g., walking barefoot) (
Site in human host. Subcutaneous, especially on the bottom of feet and between toes (
Vectored pathogens. None.
Tunga trimamillata Pampiglione et al., 2002
Geographic distribution. South America (Peru, Bolivia, Brazil) (
Natural hosts. Mammals, primarily goats, cattle, pigs. Zoonotic on humans (
Route of infection. Contact with contaminated soil (e.g., walking barefoot) (
Site in human host. Subcutaneous, especially on the bottom of feet and between toes (
Vectored pathogens. None.
●●●●●●●●●●●● Ceratophyllidae Dampf, 1908
Genus Nodopsyllus Jordan, 1933
Nodopsyllus fasciatus (Bosc, 1800)
Geographic distribution. Worldwide (
Natural hosts. Rodents. Zoonotic on humans (
Route of infection. Exposure to adults in the environment.
Site in human host. Skin.
Vectored pathogens. Hymenolepis nana (dwarf tapeworm disease), H. diminuta (rate tapeworm disease), Yersinia pestis (plague) (
Genus Oropsylla Wagner & Ioff, 1926
Oropsylla montana (Baker, 1895)
Geographic distribution. Western North America (
Natural hosts. Rodents, primarily prairie dogs and ground squirrels. Zoonotic on humans (
Route of infection. Exposure to adults in the environment.
Site in human host. Skin.
Vectored pathogens. Yersinia pestis (plague) (
●●●●●●●●●●●● Pulicidae Billberg, 1820
Genus Ctenocephalides Stiles & Collins, 1930
Ctenocephalides canis (Curtis, 1826)
Geographic distribution. Worldwide (
Natural hosts. Wild and domestic canids and felids. Zoonotic on humans (
Route of infection. Exposure to adults in the environment.
Site in human host. skin.
Vectored pathogens. Dipylidium caninum (dog tapeworm disease), Hymenolepis nana (dwarf tapeworm disease), H. diminuta (rat tapeworm disease) (
Ctenocephalides felis (Bouché, 1835)
Geographic distribution. Worldwide (
Natural hosts. Wild and domestic canids and felids. Zoonotic on humans (
Route of infection. Exposure to adults in the environment.
Site in human host. skin.
Vectored pathogens. Dipylidium caninum (dog tapeworm disease), Hymenolepis nana (dwarf tapeworm disease), H. diminuta (rate tapeworm disease), Bartonella henselae (cat-scratch disease), Rickettsia felis (feline rickettsiae), Acanthocheilonema reconditum (ocular filariasis) (
Genus Echidnophaga Olliff, 1886
Echidnophaga gallinacea (Westwood, 1875)
Geographic distribution. Worldwide (
Natural hosts. Many birds and mammals. Zoonotic on humans (
Route of infection. Exposure to adults in the environment; exposure to infected birds (
Site in human host. Skin.
Vectored pathogens. None.
Genus Synopsyllus Wagner & Roubaud, 1932
Synopsyllus fonquerniei Wagner & Roubaud, 1932
Geographic distribution. Madagascar (
Natural hosts. Rats. Zoonotic on humans (
Route of infection. Exposure to adults in the environment.
Site in human host. Skin.
Vectored pathogens. Yersinia pestis (plague) (
Genus Pulex Linnaeus, 1758
Pulex irritans Linnaeus, 1758
Geographic distribution. Worldwide (
Natural hosts. Many mammals, including humans (
Route of infection. Exposure to adults in the environment.
Site in human host. Skin.
Vectored pathogens. Dipylidium caninum (dog tapeworm disease), Hymenolepis nana (dwarf tapeworm disease), H. diminuta (rate tapeworm disease) (
Genus Xenopsylla Glinkiewicz, 1907
Xenopsylla brasiliensis (Baker, 1904)
Geographic distribution. Africa, South America, India (
Natural hosts. Rats. Zoonotic on humans (
Route of infection. Exposure to adults in the environment.
Site in human host: Skin.
Vectored pathogens. Yersinia pestis (plague) (
Xenopsylla cheopis (Rothschild, 1903)
Geographic distribution. Worldwide (
Natural hosts. Mammals, primarily rodents (rats). Zoonotic on humans (
Route of infection. Exposure to adults in the environment.
Site in human host. Skin.
Vectored pathogens. Yersinia pestis (plague), Rickettsia typhi (murine (epidemic) typhus) (
●●●●●●●●●●● Diptera Linnaeus, 1758
●●●●●●●●●●●● Phoridae Curtis, 1833
Genus Megaselia Róndani, 1856
Megaselia scalaris Loew, 1866
Geographic distribution. Worldwide (
Natural hosts. None, agent of facultative and incidental myiasis in humans (
Route of infection. Oviposition on pre-existing wounds (
Site in human host. Soft tissues, pre-existing wounds (
Notes. Although this species is known to cause facultative myiasis is pre-existing wounds of soft tissues and the upper respiratory tract (
●●●●●●●●●●●● Muscidae Latreille, 1802
Genus Musca Linnaeus, 1758
Musca domestica Linnaeus, 1758
Musca nebulo Fabricius, 1794
Musca hottentota Robineau-Desvoidy, 1830
Musca frontalis Macquart, 1843
Musca senegalensis Macquart, 1843
Musca santae-helenae Macquart, 1848
Musca gymnosomea Róndani, 1862
Musca niveisquama Thomson, 1869
Musca curviforceps Saccà & Rivosechi, 1956
Geographic distribution. Worldwide (
Natural hosts. None, agent of facultative and incidental myiasis in humans (
Route of infection. Oviposition on pre-existing wounds (
Site in human host. Skin, soft tissues, pre-existing wounds (
●●●●●●●●●●●● Fanniidae Schnabl & Dziedzicki, 1911
Genus Fannia Robineau-Desvoidy, 1830
Fannia canicularis (Linnaeus, 1761)
Geographic distribution. Worldwide (
Natural hosts. None, agent of facultative and incidental myiasis in humans (
Route of infection. Oviposition on pre-existing wounds (
Site in human host. Soft tissues, pre-existing wounds (
●●●●●●●●●●●● Calliphoridae Brauer & Bergenstamm, 1889
Genus Auchmeromyia Brauer & Bergenstamm, 1891
Auchmeromyia senegalensis Macquart, 1851
Geographic distribution. Sub-Saharan Africa, Cape Verde Islands (
Natural hosts. Several mammals, including humans (
Route of infection. Exposure to larvae in the environment (
Site in human host. Skin (sanguinivorous) (
Genus Calliphora Robineau-Desvoidy, 1820
Calliphora hilli Patton, 1925
Geographic distribution. Australia (
Natural hosts. None; causes facultative myiasis in humans (
Route of infection. Oviposition on pre-existing wounds (
Site in human host. Eye (
Calliphora vicina Robineau-Desvoidy, 1830
Geographic distribution. Worldwide (
Natural hosts. None; causes facultative myiasis in humans (
Route of infection. Oviposition on pre-existing wounds (
Site in human host. Skin, soft tissues, pre-existing wounds (
Genus Cochliomyia Townsend, 1915
Cochliomyia hominovorax (Coquerel, 1858)
Geographic distribution. Central and South America, Caribbean (
Natural hosts. Most mammals, including humans (
Route of infection. Oviposition on pre-existing wounds, ears, nose, oral cavity (
Site in human hose. Skin, soft tissues, pre-existing wounds, ears, nose, oral cavity (
Genus Chrysomya Robineau-Desvoidy, 1830
Chrysomya albiceps (Wiedemann, 1819)
Geographic distribution. Worldwide (
Natural hosts. None; causes facultative myiasis in humans and sheep (
Route of infection. Oviposition on pre-existing wounds (
Site in human host. Skin, soft tissues, pre-existing wounds (
Chrysomya bezziana (Villeneuve, 1914)
Geographic distribution. India, Arabian Peninsula, Indonesia, Philippines, New Guinea (
Natural hosts. Sheep. Zoonotic on humans as incidental hosts (
Route of infection. Oviposition on pre-existing wounds (
Site in human host. Skin, soft tissues, pre-existing wounds (
Chrysomya megacephala (Fabricius, 1794)
Geographic distribution. Worldwide (
Natural hosts. None; causes facultative myiasis in humans and other mammals (
Route of infection. Oviposition on pre-existing wounds (
Site in human host. Skin, soft tissues, pre-existing wounds (
Chrysomya rufifacies (Macquart, 1842)
Geographic distribution. Worldwide (
Natural hosts. None; causes facultative myiasis in humans and other mammals (
Route of infection. Oviposition on pre-existing wounds (
Site in human host. Skin, soft tissues, pre-existing wounds (
Genus Cordylobia Gruenberg, 1903
Cordylobia anthropophaga Blanchard, 1872
Geographic distribution. East, Central, and West Africa (
Natural hosts. Mammals, including rodents, monkeys, ruminants, and humans (
Route of infection. Exposure to first-instar larvae on fomites (soil, air-drying laundry) (
Site in human host. Skin (
Cordylobia rodhaini Gedoelst, 1910
Geographic distribution. Tropical Africa (
Natural hosts. Mammals, primarily rodents. Zoonotic on humans (
Route of infection. Exposure to larvae on fomites (soil, air-drying laundry) (
Site in human host. Skin (
Genus Lucilia Robineau-Desvoidy, 1830
Lucilia cuprina (Wiedemann, 1830)
Geographic distribution. Nearly worldwide, more common in warm climates (
Natural hosts. None, causes facultative myiasis in sheep and humans (
Route of infection. Oviposition on pre-existing wounds (
Site in human host. Skin, soft tissues, pre-existing wounds (
Lucilia sericata (Meigan, 1826)
Geographic distribution. Europe, North, Central, and South America (
Natural hosts. None, causes facultative myiasis in sheep and humans (
Route of infection. Oviposition on pre-existing wounds (
Site in human host. Skin, soft tissues, pre-existing wounds (
Vectored pathogens. Wohlfahrtiimonas chitiniclastica, Ignatzschineria indica (
Genus Phormia Robineau-Desvoidy, 1830
Phormia regina (Meigen, 1826)
Geographic distribution. Northern Hemisphere (
Natural hosts. None, causes facultative myiasis in humans (
Route of infection. Oviposition on pre-existing wounds (
Site in human host. Skin, soft tissues, pre-existing wounds (
Genus Protophormia Townsend, 1908
Protophormia terraenovae Robineau-Desvoidy, 1830
Geographic distribution. Northern Hemisphere (
Natural hosts. None, causes facultative myiasis in humans (
Route of infection. Oviposition on pre-existing wounds (
Site in human host. Skin, soft tissues, pre-existing wounds (
●●●●●●●●●●●● Sarcophagidae Macquart, 1834
Genus Peckia Robineau-Desvoidy, 1830
Peckia lambens (Wiedemann, 1830)
Geographic distribution. Central and South America, Caribbean (
Natural hosts. None; cause facultative myiasis in humans (
Route of infection. Oviposition on pre-existing wounds (
Site in human host. Skin and soft tissues (
Genus Sarcophaga Meigen, 1826
Sarcophaga dux Thomson, 1869
Geographic distribution. Worldwide (
Natural hosts. None, causes facultative myiasis in humans (
Route of infection. Oviposition on pre-existing wounds, ear (
Site in human host. Ear, skin and soft tissues (
Sarcophaga peregrina (Robineau-Desvoidy, 1830)
Sarcophaga fucicauda Böttcher, 1912
Sarcophaga hutsoni Parker, 1923
Sarcophaga meriana Zumpt, 1951
Geographic distribution. Asia, Africa, Australia, New Zealand (
Natural hosts. None, causes facultative myiasis in humans (
Route of infection. Oviposition on pre-existing wounds, ear, eye (
Site in human host. Nose, oral cavity, eye (
Sarcophaga pernix Harris, 1789
Musca haemorrhoidalis Fallén, 1817
Geographic distribution. Europe, Asia, North Africa (
Natural hosts. None, causes facultative myiasis in humans (
Route of infection. Oviposition on pre-existing wounds, ear (
Site in human host. Ear, skin and soft tissues (
Sarcophaga ruficornis (Fabricius, 1794)
Geographic distribution. Worldwide (
Natural hosts. None, causes facultative myiasis in humans (
Route of infection. Oviposition on pre-existing wounds (
Site in human host. Skin and soft tissues (
Sarcophaga septentrionalis (Rohdendorf, 1937)
Geographic distribution. East Asia (
Natural hosts. None; causes facultative myiasis in humans (
Route of infection. Oviposition on pre-existing wounds (
Site in human host. Oral cavity (
Genus Wohlfahrtia Brauer & von Bergenstamm, 1889
Wohlfahrtia magnifica (Schiner, 1861)
Geographic distribution. Mediterranean Europe, North Africa, Central and Southeast Asia, Russia (
Natural hosts. Mammals and birds, including sheep, cattle, poultry, and humans (
Route of infection. Larviposition on wounds, tissues (
Site in human host. Skin, soft tissues, pre-existing wounds, oral cavity, ears (
Vectored pathogens. Wohlfahrtiimonas chitiniclastica, Ignatzschineria indica (
Wohlfahrtia opaca (Coquillett, 1897)
Geographic distribution. Western North America (
Natural hosts. Wild and domestic canids and felids, rabbits, mustelids. Zoonotic in human as incidental hosts (
Route of infection. Larviposition on wounds, tissues (
Site in human host. Skin and soft tissues, pre-existing wounds (
Wohlfahrtia vigil (Walker, 1849)
Geographic distribution. Eastern North America, southern Europe, Russia, Pakistan (
Natural hosts. Wild and domestic canids and felids, rabbits, mustelids. Zoonotic in human as incidental hosts (
Route of infection. Larviposition on wounds, tissues (
Site in human host. Skin and soft tissues, pre-existing wounds (
●●●●●●●●●●●● Oestridae Leach, 1815
Genus Alouattamyia Townsend, 1931
Allouattamyia baeri (Shannon & Green, 1926)
Geographic distribution. South America (
Natural hosts. Non-human primates. Zoonotic in human as incidental hosts (
Route of infection. Exposure to first-instar larvae in the environment (
Site in human host. Upper respiratory tract (
Genus Dermatobia Brauer, 1860
Dermatobia hominis (Linnaeus in Pallas, 1781)
Geographic distribution. Central and South America, Caribbean (
Natural hosts. Many mammals, including humans, and birds; vectored by mosquitoes and ticks (
Route of infection. Bite of a mosquito or tick, the phoretic host for D. hominis eggs (
Site in human host. Skin (
Genus Cuterebra Clark, 1815
Geographic distribution. North and Central America (
Natural hosts. Rodents and lagomorphs; cats and other mammals can serve as reservoir hosts. Zoonotic in human as incidental hosts (
Route of infection. Exposure to first-instar larvae in contaminated soil, litter, etc.
Site in human host. Skin (second-instar, third-instar larvae), viscera and lungs (third-instar larvae) (
Notes. Cases of human infestation with Cuterebra are usually not identified to the species level.
Genus Gasterophilus Leach, 1817
Geographic distribution. Worldwide (
Natural hosts. Horses, zebras, elephants, rhinoceroses. Zoonotic in human as incidental hosts (
Route of infection. Oviposition on skin and mucus membranes (
Site in human host. Skin, eye, oral cavity (
Notes. Cases of human infestation with Gasterophilus are usually not identified to the species level.
Genus Hypoderma Latreille, 1818
Hypoderma bovis (Linnaeus, 1758)
Geographic distribution. North America, Europe, Asia, Africa (
Natural hosts. Wild and domestic ruminants. Zoonotic in human as incidental hosts (
Route of infection. Oviposition on hair or skin, or possibly direct contact with first-instar larvae on infected animals (
Site in human host. Skin (
Hypoderma lineatum (Viller, 1789)
Geographic distribution. North America, Europe, Asia, Africa (
Natural hosts. Wild and domestic ruminants. Zoonotic in human as incidental hosts (
Route of infection. Oviposition on hair or skin, or possibly direct contact with first-instar larvae on infected animals (
Site in human host. Skin (
Hypoderma tarandi (Linnaeus, 1758)
Geographic distribution. Northern North America, Northern Eurasia (
Natural hosts. Caribou. Zoonotic in human as incidental hosts (
Route of infection. Oviposition on hair, skin, or mucus membranes, or possibly direct contact with first-instar larvae on infected animals (
Site in human host. Skin, eyes, oral cavity (
Genus Oestrus Linnaeus, 1758
Oestrus ovis Linnaeus, 1758
Geographic distribution. Worldwide (
Natural hosts. Sheep, goats, other ruminants. Zoonotic in human as incidental hosts (
Route of infection. Larviposition on eyes and mucus membranes (
Site in human host. Eye, throat (
●●●●● Nematoda Diesking, 1861
●●●●●● Dorylaimia Inglis, 1983
●●●●●●● Dioctophymatida Baylis & Daubney, 1926
●●●●●●●● Dioctophymidae Railliet, 1915
Genus Dioctoyphyme Collet-Meygret, 1802
Dioctophyma, misspelling
Dioctophyme renale (Goeze, 1782)
Geographic distribution. Worldwide (
Natural hosts. First intermediate hosts are annelids. Second intermediate and paratenic hosts are primarily freshwater fish and amphibians. Definitive hosts are carnivores, including mustelids and canids. Zoonotic in humans, harboring L3 larvae or adults (
Route of infection. Ingestion of L3 larvae in undercooked paratenic hosts (
Site in human host. Subcutaneous (L3 larvae), kidneys (adults) (
Genus Eustrongylides Jägerskiöld, 1909
Geographic distribution. Worldwide (
Natural hosts. First intermediate hosts are aquatic annelids. The second intermediate hosts are fish; fish, amphibians, and reptiles can serve as paratenic hosts. Definitive hosts are birds. Zoonotic in humans as dead-end hosts harboring L3 or L4 larvae (
Route of Infection. Ingestion of L3 or precocious L4 larvae in infected intermediate or paratenic hosts (
Site in human host. Skin, Abdominal and peritoneal cavities, possible ectopic migration to other parts of the body (
Notes. There about 20 described species of Eustrongylides. Human cases with larval Eustrongylides have been reported from North America and East Africa and have not been characterized at the species level.
●●●●●●● Trichinellida Hall, 1916
Trichocephalida Spasski, 1954
●●●●●●●● Anatrichosomatidae Yamaguti, 1961
Genus Anatrichosoma Smith & Chitwood, 1954
Geographic distribution. Worldwide (
Natural hosts. The life cycle is not completely understood, and it is not known if there are more than one host. Definitive hosts include non-human primates, tree shrews, rodents, marsupials. Zoonotic in humans as incidental hosts (
Route of infection. Unknown, possible ingestion of embryonated eggs or unknown intermediate host (
Site in human host. Skin and soft tissues, oral mucosa (
Notes. Human cases of anatrichosomiasis have been diagnosed by histopathology. Because Anatrichosoma spp. have not been described morphologically by histopathology, it is not currently possible to characterize human isolates at the species level. Given the morphology and epidemiology, cases from the human oral cavity from Mexico and the United States are probably attributable to A. buccalis Pence & Little, 1972 (
●●●●●●●● Capillariidae Railliet, 1915
Genus Calodium Dujardin, 1845
Calodium hepaticum (Bancroft, 1893)
Geographic distribution. Worldwide (
Natural hosts. Rodents. Zoonotic in humans as incidental hosts (
Route of infection. Ingestion of embryonated eggs on soil-contaminated fomites (
Site in human host. Liver (
Notes. Eggs of C. hepaticum detected in human stool probably represent spurious passage and not true infection.
Genus Eucoleus Dujardin, 1845
Eucoleus aerophilus (Creplin, 1839)
Geographic distribution. Worldwide (
Natural hosts. Paratenic hosts are earthworms. Definitive hosts are carnivores. Zoonotic in humans as incidental hosts (
Route of infection. Ingestion of embryonated eggs or paratenic hosts (
Site in human host. Lungs (
Genus Paracapillaria Chitwood et al., 1968
Paracapillaria philippinensis (Velasquez et al., 1968)
Geographic distribution. Southeast Asia, Philippines, Egypt, South America (
Natural hosts. Intermediate hosts are freshwater fish. Definitive hosts are humans, fish-eating birds (
Route of infection. Ingestion of L1 larvae in infected intermediate host (
Site in human host. Small intestine (
●●●●●●●● Trichinellidae Ward, 1907
Genus Trichinella Railliet, 1895
Trichinella britovi Pozio et al., 1992
Trichinella strain T3
Geographic distribution. Europe, North America, Asia, West Africa (
Natural hosts. Mammals. Zoonotic in humans (
Route of infection. Ingestion of L1 larvae in infected hosts; common sources of human infection are wild and domestic pigs, horses, foxes, jackals (
Site in human host. Small intestine (adults), skeletal muscle (L1 larvae) (
Trichinella murelli Pozio & La Rosa, 2000
Trichinella strain T5
Geographic distribution. North America (
Natural hosts. Mammals, primarily carnivores. Zoonotic in humans (
Route of infection. Ingestion of L1 larvae in infected hosts; common sources of human are bears and horses (
Site in human host. Small intestine (adults), skeletal muscle (L1 larvae) (
Trichinella nativa Britov & Boev, 1972
Trichinella strain T2
Geographic distribution. Circumboreal (
Natural hosts. Mammals, primarily carnivores. Zoonotic in humans (
Route of infection. Ingestion of L1 larvae in infected hosts; common sources of human infection are bears and walrus (
Site in human host. Small intestine (adults), skeletal muscle (L1 larvae) (
Trichinella nelsoni Britov & Boev, 1972
Trichinella strain T7
Geographic distribution. Europe, North America, Asia, West Africa (
Natural hosts. Mammals. Zoonotic in humans (
Route of infection. Ingestion of L1 larvae in infected hosts; common sources of human infection are wild and domestic pigs, horses, foxes, jackals (
Site in human host. Small intestine (adults), skeletal muscle (L1 larvae) (
Trichinella papuae Pozio et al., 1999
Geographic distribution. Papua New Guinea, Thailand (
Natural hosts. Mammals (primarily pigs), saltwater crocodiles. Zoonotic in humans (
Route of infection. Ingestion of L1 larvae in infected hosts; common sources of human infection are wild and domestic pigs (
Site in human host. Small intestine (adults), skeletal muscle (L1 larvae) (
Trichinella pseudospiralis Garkavi, 1972
Trichinella strain T4
Geographic distribution. Worldwide (
Natural hosts. Mammals and birds. Zoonotic in humans (
Route of infection. Ingestion of L1 larvae in infected hosts; common sources of human infection are wild and domestic pigs (
Site in human host. Small intestine (adults), skeletal muscle (L1 larvae) (
Trichinella spiralis (Owen, 1835)
Trichinella strain T1
Geographic distribution. Worldwide (
Natural hosts. Mammals. Zoonotic in humans (
Route of infection. Ingestion of L1 larvae in infected hosts; common sources of human infection are wild and domestic pigs (
Site in human host. Small intestine (adults), skeletal muscle (L1 larvae) (
Trichinella Strain T6
Geographic distribution. Northern and montane North America (
Natural hosts. Mammals, primarily carnivores. Zoonotic in humans (
Route of infection. Ingestion of L1 larvae in infected hosts; common sources of human infection are bears, wild felids (
Site in human host. Small intestine (adults), skeletal muscle (L1 larvae) (
●●●●●●● Muspiceida Bain & Chabaud, 1959
●●●●●●●● Robertdollfusidae Chabaud & Campana, 1950
Genus Haycocknema Spratt et al., 1999
Haycocknema perplexum Spratt et al., 1999
Geographic distribution. Australia (
Natural hosts. Unknown, presumed zoonotic in humans (
Route of infection. Unknown, presumed ingestion of larvae in natural hosts (
Site in human host. Skeletal muscle (
●●●●●●●● Trichuridae Ransom, 1911
Genus Trichuris Roederer, 1761
Trichuris trichiura (Linnaeus, 1771)
Geographic distribution. Worldwide (
Natural hosts. Humans (
Route of infection. Ingestion of embryonated eggs in fecally contaminated food, water, fomites (
Site in human host. Large intestine (
Notes. The zoonotic potential of T. trichiura is not well understood and is unclear whether there are multiple species infecting humans or whether other animals can harbor T. trichiura and serve as reservoir hosts for human infection (
Trichuris vulpis Froelich, 1789
Geographic distribution. Worldwide (
Natural hosts. Wild and domestic canids. Zoonotic in humans (
Route of infection. Ingestion of embryonated eggs (
Site in human host. Large intestine (
Notes. Fully-embryonated eggs of T. vulpis in human stool specimens may also represent spurious passage and not true infection.
●●●●●● Chromadoria Inglis, 1983
●●●●●●● Spururina Railliet & Henry, 1915
●●●●●●●● Ascaridida DeLay & Blaxter, 2002
●●●●●●●●● Anisakidae Skrjabin & Karokhin, 1945
Genus Anisakis Dujardin, 1845
Geographic distribution. Worldwide; human infection more common in coastal areas (
Natural hosts. First intermediate hosts are marine microcrustaceans. Paratenic hosts are marine fish and squid. Definitive hosts are fish-eating mammals, primarily cetaceans and pinnipeds. Zoonotic in humans as dead-end hosts harboring L3 larvae (
Route of infection. Ingestion of L3 larvae in infected paratenic hosts (
Site in human host. Stomach, esophagus, oral cavity, large intestine; ectopic colonization of peritoneal cavity, mesenteries, omentum, mesocolic lymph nodes, spleen, pleural cavity, and parametrium (
Notes. While most human cases have been attributed to members of A. simplex sensu lato (including A. simplex (Rudolphi, 1809), A. pegreffii (Campana-Rouget & Biocca, 1955), and A. berlandi Mattiucci et al. 2014) or A. physeteris (Baylis, 1923), reliable identification human isolates at the species level is difficult and seldom performed due to a lack of species-level morphologic features of the L3 larvae (the stage found in human host) and the lack of a reliable sequencing library for molecular analysis (
Genus Contracaecum Railliet & Henry, 1912
Geographic distribution. Worldwide; human infection more common on coastal areas (
Natural hosts. First intermediate hosts are marine microcrustaceans. Paratenic hosts are marine fish and squid. Definitive hosts are fish-eating mammals, primarily cetaceans and pinnipeds, and birds. Zoonotic in humans as dead-end hosts harboring L3 larvae (
Route of infection. Ingestion of L3 larvae in infected paratenic hosts (
Site in human host. Stomach, esophagus, oral cavity, large intestine; ectopic colonization of various organs possible (
Notes. It is not currently possible to reliably identify human isolates of Contracaecum at the species level due to a lack of species-level morphologic features of the L3 larvae (the stage found in human host) and the lack of a reliable sequencing library for molecular analysis.
Genus Pseudoterranova Mozgovoi, 1951
Phocanema Myers, 1959
Geographic distribution. Worldwide; human infection more common on coastal areas (
Natural hosts. First intermediate hosts are marine microcrustaceans. Paratenic hosts are marine fish and squid. Definitive hosts are fish-eating mammals, primarily cetaceans and pinnipeds. Zoonotic in humans as dead-end hosts harboring L3 larvae (
Route of infection. Ingestion of L3 larvae in infected paratenic hosts (
Site in human host. Stomach, esophagus, oral cavity, large intestine; ectopic colonization of peritoneal cavity, mesenteries, omentum, mesocolic lymph nodes, spleen, pleural cavity, and parametrium (
Notes. While many human cases have been attributed to the P. decepiens (Krabbe, 1878) complex, reliable identification human isolates at the species level is difficult and seldom performed due to a lack of species-level morphologic features of the L3 larvae (the stage found in human host) and the lack of a reliable sequencing library for molecular analysis.
●●●●●●●●● Ascarididae Baird, 1853
Genus Ascaris Linnaeus, 1758
Ascaris lumbricoides Linnaeus, 1758
Ascaris suum (Goeze, 1782)
Geographic distribution. Worldwide (
Natural hosts. Pigs. Zoonotic in humans (
Route of infection. Ingestion of embryonated eggs in fecally contaminated food, water, fomites (
Site in human host. Lungs (L3 larvae); Small intestine (adults), with ectopic colonization of liver, spleen, gall bladder (
Notes. The relationship between A. lumbricoides and A. suum is unresolved. While there are genetic differences among Ascaris isolates throughout the world, it is unclear whether such differences represent more than one species with a common ancestor, multiple colonization events between pigs and humans in different geographical areas, or there is one species with geographic variations (
Genus Baylisascaris Sprent, 1968
Baylisascaris procyonis (Stefanski & Zarnowski, 1951)
Geographic distribution. North and Central America, introduced to Europe and Asia (
Natural hosts. Raccoons and other procyonids; dogs can serve as reservoir hosts. Zoonotic in humans as dead-end hosts harboring L3 larvae (
Route of infection. Ingestion of embryonated eggs in food, water, fomites contaminated with raccoon feces; possibly also ingestion of paratenic hosts (
Site in human host. Brain, eye, liver, lungs (
Genus Lagochilascaris Leiper, 1909
Lagochilascaris minor Leiper, 1909
Geographic distribution. Central and South America (
Natural hosts. Unknown. It has been prosed rodents are intermediate hosts and carnivores are definitive hosts, with humans serving as incidental definitive hosts (
Route of infection. Unknown, presumed to be ingestion of larvae in infected intermediate or paratenic hosts, possibly ingestion of embryonated eggs (
Site in human host. Disseminated infection; common sites of infection are subcutaneous, ear, tonsils, nasal sinuses, and mastoid (
Genus Toxocara Stiles, 1905
Toxocara canis (Werner, 1792)
Geographic distribution. Worldwide (
Natural hosts. Wild and domestic canids. Zoonotic in humans as dead-end hosts harboring L3 larvae (
Route of infection. Ingestion of embryonated eggs in food, water, fomites contaminated with canid feces (
Site in human host. Disseminated infection; common sites of infection are liver, eye, CNS, and lungs (
Toxocara cati Schrank, 1788
Toxocara mystax (Zeder, 1800)
Geographic distribution. Worldwide (
Natural hosts. Wild and domestic felids. Zoonotic in humans as dead-end hosts harboring L3 larvae (
Route of infection. Ingestion of embryonated eggs in food, water, fomites contaminated with felid feces (
Site in human host. Disseminated infection; common sites of infection are liver, eye, CNS, and lungs (
●●●●●●●● Oxyurida Weinland, 1858
●●●●●●●●● Oxyuridae Cobbold, 1864
Genus Enterobius Baird, 1853
Enterobius vermicularis (Linnaeus, 1758)
Enterobius gregorii Hugot, 1983
Geographic distribution. Worldwide (
Natural hosts. Humans (
Route of infection. Ingestion of embryonated eggs on contaminated fomites (
Site in human host. Cecum, large intestine, appendix; ectopic colonization of female urogenital tract (
Genus Syphacia Seurat, 1916
Syphacia oblevata (Rudolphi, 1802)
Geographic distribution. Worldwide (
Natural hosts. Rodents (
Route of infection. Presumed ingestion of embryonated eggs on contaminated fomites (
Site in human host. Large intestine (
●●●●●●●● Spirudida De Ley & Blaxter, 2002
●●●●●●●●● Filarioidea Chabaoud & Anderson, 1959
●●●●●●●●●● Onchocercidae Chabaud & Anderson, 1959
Genus Acanthocheilonema Cobbold, 1870
Acanthocheilonema reconditum (Grassi, 1889)
Geographic distribution. Worldwide (
Natural hosts. Vector intermediate hosts are fleas and lice, primarily the cat flea (Ctenocephalides felis). Definitive hosts are canids. Zoonotic in humans (
Route of infection. Introduction of L3 larvae via the bite of an infected flea (
Site in human host. Eyes (
Notes. Several cases of Acanthocheilonema-like nematodes recovered from human eyes have been reported, though not identified further (
Genus Breinlia Yorke & Maplestone, 1926
Breinlia annulipapillata (Johnston & Mawson, 1938)
Geographic distribution. Australia (
Natural hosts. Vector intermediate hosts are mosquitoes, although the full range of competent genera is not known. Definitive hosts are kangaroos and wallabies. Zoonotic in humans (
Route of infection. Introduction of L3 larvae via the bite of an infected mosquito (
Site in human host. Eye (
Genus Brugia Buckley, 1960
Brugia malayi (Brug, 1927)
Geographic distribution. Southeast Asia, including Philippines, Malaysia, Indonesia, South Korea, Vietnam, India (
Natural hosts. Vector intermediate hosts are mosquitoes, primarily in the genera Aedes and Mansonia. Definitive hosts are humans (
Route of infection. Introduction of L3 larvae via the bite of an infected mosquito (
Site in human host. Lymphatic system (
Brugia timori Partono et al., 1977
Geographic distribution. Lesser Sunda Archipelago, including the islands of Timor, Sumba, Lembata, Pentar, Alor (
Natural hosts. Vector intermediate hosts are mosquitoes in the genus Anopheles. Definitive hosts are humans (
Route of infection. Introduction of L3 larvae via the bite of an infected mosquito (
Site in human host. Lymphatic system (
Unassigned Brugia species:
American Brugia spp.
Geographic distribution. North, Central, and South America (
Natural hosts. Unknown. Vector intermediate hosts are presumed to be mosquitoes. Possible definitive hosts include raccoons, rabbits, and felids. Presumed zoonotic in humans (
Route of infection. Introduction of L3 larvae via the bite of an infected mosquito (
Site in human host. Lymphatic system (
Notes. Several cases of zoonotic Brugia spp. have reported in the Americas. The precise identification of the causal agents is not known due to limited information on the morphologic features observed on histopath. Human infection in North America has been tentatively attributed to B. beaveri Ash & Little, 1964 or B. lepori Eberhard, 1984 (
Genus Dirofilaria Railliet & Henry, 1911
Subgenus Dirofilaria Railliet & Henry, 1911
Dirofilaria (D.) immitis (Leidy, 1856)
Filaria magalhaesi Blanchard, 1896
Dirofilaria nasuae Mazza, 1926
Dirofilaria pongoi Vogel & Vogelsang, 1930
Dirofilaria louisianensis Faust et al., 1941
Geographic distribution. Worldwide (
Natural hosts. Vector intermediate hosts are mosquitoes. Definitive hosts are primarily wild and domestic canids. Zoonotic in humans (
Route of infection. Introduction of L3 larvae via the bite of an infected mosquito (
Site in human host. Heart, pulmonary vessels (
Dirofilaria (D.) spectans Freitas & Lint, 1949
Geographic distribution. South America (
Natural hosts. Vector intermediate hosts are presumed to be mosquitoes. Definitive hosts is the giant river otter (Pteronura brasiliensis). Zoonotic in humans (
Route of infection. Introduction of L3 larvae via the bite of an infected mosquito (
Site in human host. Digital artery (
Notes. Few features can separate D. spectans from D. immitis, thus the validity of the species and its involvement in human infections remain in question.
Subgenus Nochtiella Faust, 1937
Dirofilaria (N.) repens Railliet & Henry, 1911
Filaria confunctivae Addario, 1885, in part
Geographic distribution. Europe, Africa, Asia (
Natural hosts. Vector intermediate hosts are mosquitoes. Definitive hosts are carnivores, primarily wild and domestic canids, also felids. Zoonotic in humans (
Route of infection. Introduction of L3 larvae via the bite of an infected mosquito (
Site in human host. Skin; ectopic migration to the eye (
Dirofilaria (N.) striata (Molin, 1858)
Geographic distribution. North, Central, and South America (
Natural hosts. Vector intermediate hosts are mosquitoes. Definitive hosts are wild felids. Zoonotic in humans (
Route of infection. Introduction of L3 larvae via the bite of an infected mosquito (
Site in human host. Eye (
Dirofilaria (N.) subdermata (Monnig, 1924)
Geographic distribution. North America (
Natural hosts. Vector intermediate hosts are mosquitoes. Definitive hosts are porcupines. Zoonotic in humans (
Route of infection. Introduction of L3 larvae via the bite of an infected mosquito (
Site in human host. Skin (
Notes. Features available in transverse histologic sections are unable to reliably distinguish D. subdermata from D. ursi; therefore, specimens recovered from human cases are generally reported as “D. ursi-like”.
Dirofilaria (N.) tenuis Chandler, 1942
Filaria confunctivae Addario, 1885, in part
Geographic distribution. North America (
Natural hosts. Vector intermediate hosts are mosquitoes. Definitive hosts are primarily raccoons. Zoonotic in humans (
Route of infection. Introduction of L3 larvae via the bite of an infected mosquito (
Site in human host. Skin; ectopic migration to the eyes (
Dirofilaria (N.) ursi Yamaguti, 1941
Geographic distribution. North America, Russia, Japan (
Natural hosts. Vector intermediate hosts are black flies in the genus Simulium. Definitive hosts are bears. Zoonotic in humans (
Route of infection. Introduction of L3 larvae via the bite of an infected black fly (
Site in human host. Skin (
Notes. Features available in transverse histologic sections are unable to reliably distinguish D. subdermata from D. ursi; therefore, specimens recovered from human cases are generally reported as “D. ursi-like”.
Dirofilaria , incertae sedis:
Dirofilaria sp. Genotype Hong Kong
Dirofilaria hongkongensis
Geographic distribution. Southeast Asia (
Natural hosts. Vector intermediate hosts are unknown. Definitive hosts are canids. Zoonotic in humans (
Route of infection. Presumably via the introduction of L3 larvae via the bite of an infected vector.
Site in human host. Skin (
Notes. Dirofilaria honkongensis was described from dogs and humans in Hong Kong based on molecular characterization (
Genus Dunnifilaria Mullin & Balastingam, 1973
Geographic distribution. Mexico, Southeast Asia (
Natural hosts. Vector intermediate hosts are unknown. Definitive hosts are rodents. Zoonotic in humans (
Route of Infection. Presumed introduction of L3 larvae via the bite of an infected vector.
Site in human host. Eye (
Notes. The single human case was reported from the eye of a patient in Malaysia (
Genus Loa Stiles, 1905
Loa loa (Cobbold, 1864)
Geographic distribution. West-central Africa (
Natural hosts. Vector intermediate hosts are deer flies in the genus Chrysops. Definitive hosts are humans (
Route of infection. Introduction of L3 larvae via the bite of an infected deer fly (
Site in human host. Skin; ectopic migration to the eyes (
Notes. Cases of L. loa in non-travelers outside of endemic areas should be considered as possible misidentifications. There are many case reports of L. loa from India, many of which appear to represent misidentifications of Dirofilaria (prob. D. repens).
Genus Mansonella Faust, 1929
Mansonella ozzardi Manson, 1897
Geographic distribution. Central and South America, Caribbean (
Natural hosts. Vector intermediate hosts are biting midges (genus Culicoides) and black flies (genus Simulium). Definitive hosts are humans (
Route of infection. Introduction of L3 larvae via the bite of an infected arthropod vector (
Site in human host. Skin (
Mansonella perstans (Manson, 1891)
Dipetalonema berghei Chardome & Peel, 1951
Geographic distribution. Africa, South America, Caribbean (
Natural hosts. Vector intermediate hosts are biting midges in the genus Culicoides. Definitive hosts are humans (
Route of infection. Introduction of L3 larvae via the bite of an infected Culicoides biting midge (
Site in human host. Peritoneal cavity, pleural cavity, pericardium, mesenteries (
Mansonella streptocerca (MacFie & Corson, 1922)
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Vector intermediate hosts are biting midges in the genus Culicoides. Definitive hosts are humans, non-human primates (
Route of infection. Introduction of L3 larvae via the bite of an infected Culicoides biting midge (
Site in human host. Skin (
Genus Meningonema Orihel & Esslinger, 1973
Meningonema peruzzii Orihel & Esslinger, 1973
Geographic distribution. Africa (
Natural hosts. Vector intermediate hosts are unknown. Definitive hosts are monkeys. Zoonotic in humans (
Route of infection. Introduction of L3 larvae via the bite of an infected arthropod vector (
Site in human host. CNS (
Genus Molinema Freitas & Lint, 1939
Geographic distribution. North, Central, and South America (
Natural hosts. Vector intermediate hosts are mosquitoes. Definitive hosts are rodents. Zoonotic in humans (
Route of infection. Introduction of L3 larvae via the bite of an infected mosquito (
Site in human host. Eyes (
Notes. Human cases of Molinema are rare. Cases from the northwestern United States are believed to be attributed to either M. arbuta (Highby, 1943), a parasite of porcupines, or M. sprenti (Anderson, 1953), a parasites of beaver (
Genus Onchocerca Diesing, 1841
Onchocerca cervicalis Railliet & Henry, 1910
Geographic distribution. Worldwide (
Natural hosts. Vector intermediate hosts are biting midges in the genus Culicoides. Definitive hosts are horses and other equids. Zoonotic in humans (
Route of infection. Introduction of L3 larvae via the bite of an infected black fly (
Site in human host. Skin, eyes (Burr et al. 1998;
Onchocerca dewittei japonica Uni et al., 2001
Geographic distribution. Japan (
Natural hosts. Vector intermediate hosts are black flies in the genus Simulium. Definitive hosts are wild pigs. Zoonotic in humans (
Route of infection. Introduction of L3 larvae via the bite of an infected black fly (
Site in human host. Skin (
Onchocerca gutturosa (Neumann, 1919)
Geographic distribution. Africa, Europe, Asia, Australia (
Natural hosts. Vector intermediate hosts are biting midges in the genus Culicoides. Definitive hosts are cattle. Zoonotic in humans (
Route of infection. Introduction of L3 larvae via the bite of an infected black fly (
Site in human host. Skin (
Onchocerca jakutensis (Gubanov, 1964)
Geographic distribution. Europe, Asia (
Natural hosts. Vector intermediate hosts are black flies in the genus Simulium. Definitive hosts are deer. Zoonotic in humans (
Route of infection. Introduction of L3 larvae via the bite of an infected black fly (
Site in human host. Skin, eyes (
Onchocerca lupi Rodonaja, 1967
Geographic distribution. Europe, Asia, North America (
Natural hosts. Putative vector intermediate hosts are black flies in the genus Simulium. Definitive hosts are wild and domestic canids and felids. Zoonotic in humans (
Route of infection. Introduction of L3 larvae via the bite of an infected black fly (
Site in human host. Skin, skeletal muscle, cervical nodules (
Onchocerca volvulus (Leuckart, 1893)
Geographic distribution. Sub-Saharan Africa, Yemen, Central and South America (
Natural hosts. Vector intermediate hosts are black flies in the genus Simulium. Definitive hosts are humans (
Route of infection. Introduction of L3 larvae via the bite of an infected black fly (
Site in human host. Skin, subcutaneous nodules (
Genus Pelecitus Railliet & Henry, 1910
Geographic distribution. Worldwide (
Natural hosts. Vector intermediate hosts are various avian live, mosquitoes, and tabanid flies. Definitive hosts are birds, lagomorphs, and marsupials. Zoonotic in humans (
Route of infection. Introduction of L3 larva via the bite of an infected mosquito (
Site in human host. Eyes (
Notes. The single case of human infection with Pelecitus was from Brazil and was not identified to the species level (
Genus Wuchereria Da Silva Araujo, 1877
Wuchereria bancrofti (Cobbold, 1877)
Wuchereria pacifica Manson-Bahr, 1941
Geographic distribution. Circumtropical, including South America, Caribbean, Africa, Asia, and Pacific Islands (
Natural hosts. Vector intermediate hosts are mosquitoes, including the genera Aedes, Anopheles, and Culex. Definitive hosts are humans (
Route of infection. Introduction of L3 larvae via the bite of an infected mosquito (
Site in human host. Lymphatic system (
●●●●●●●●●● Setariidae Skrjabin & Shikhobalova, 1945
Genus Setaria Viborg, 1795
Setaria equina (Abildgaard, 1789)
Geographic distribution. Worldwide (
Natural hosts. Vector intermediate hosts are believed to be mosquitoes in the genera Aedes or Culex. Definitive hosts are horses and other equids. Zoonotic in humans (
Route of infection. Introduction of L3 larvae via the bite of an infected mosquito (
Site in human host. Eyes (
Setaria labiatopapillosa (Allessandrini, 1838)
Geographic distribution. Worldwide (
Natural hosts. Vector intermediate hosts are believed to be mosquitoes in the genus Aedes. Definitive hosts are bovids. Zoonotic in humans (
Route of infection. Introduction of L3 larvae via the bite of an infected mosquito (
Site in human host. Eyes (
Filaroidea, incertae sedis:
“Microfilaria” bolivarensis (Godoy et al., 1980)
Geographic distribution. Venezuela (
Natural hosts. Unknown; presumed to be zoonotic in humans (
Route of infection. Presumed introduction of L3 larvae via the bite of an infected arthropod vector.
Site in human host. Unknown, only described from microfilariae in blood (
“Microfilaria” rodhaini (Peel & Chardome, 1946)
Geographic distribution. Gabon (
Natural hosts. Vector intermediate hosts unknown. Definitive hosts presumed to be bonobos and chimpanzees. Zoonotic in humans (
Route of infection. Presumed introduction of L3 larvae via the bite of an infected arthropod vector
Site in human host. Unknown, only described from microfilariae in blood (
“Microfilaria” semiclarum (Fain, 1974)
Geographic distribution. Democratic Republic of Congo (
Natural hosts. Unknown; presumed to be zoonotic in humans (
Route of infection. Presumed introduction of L3 larvae via the bite of an infected arthropod vector.
Site in human host. Unknown, only described from microfilariae in blood (
●●●●●●●●●● Spiruroidea Oerley, 1885
●●●●●●●●●●● Gongylonematidae Sobolev, 1949
Genus Gongylonema Molin, 1857
Gongylonema pulchrum Molin, 1857
Geographic distribution. Worldwide (
Natural hosts. Intermediate hosts are insects, primarily coprophagous beetles and cockroaches. Definitive hosts are mammals, including ruminants, carnivores, insectivores, lagomorphs. Zoonotic in humans (
Route of infection. Ingestion of L3 larvae in infected insects (
Site in human host. Oral mucosa (
●●●●●●●●●●● Gnathostomatidae Railliet, 1895
Genus Gnathostoma Owen, 1837
Gnathostoma binucleatum (Almeyda-Artigas, 1991)
Geographic distribution. Central and South America (
Natural hosts. First intermediate hosts are freshwater copepods. Second intermediate hosts are freshwater fish, amphibians, birds, rodents, and reptiles can serve as paratenic hosts. Definitive hosts are wild and domestic felids and canids. Zoonotic in humans as dead-end hosts harboring L3 larvae (
Route of infection. Ingestion of L3 larvae in infected intermediate or paratenic hosts (
Site in human host. Skin, heart, intestinal tract, ears, eyes, CNS (
Gnathostoma doloresi (Tubangui, 1925)
Geographic distribution. Southeast Asia, Japan (
Natural hosts. First intermediate hosts are freshwater copepods. Second intermediate hosts are freshwater fish. Amphibians, birds, rodents, and reptiles can serve as paratenic hosts. Definitive hosts are wild and domestic pigs. Zoonotic in humans as dead-end hosts harboring L3 larvae (
Route of infection. Ingestion of L3 larvae in infected intermediate or paratenic hosts (
Site in human host. Skin, heart, intestinal tract, ears, eyes, CNS (
Gnathostoma hispidum (Fedtschenko, 1872)
Geographic distribution. Southeast Asia, India, Australia (
Natural hosts. First intermediate hosts are freshwater copepods. Second intermediate hosts are freshwater fish. Amphibians, birds, rodents, and reptiles can serve as paratenic hosts. Definitive hosts are wild and domestic pigs. Zoonotic in humans as dead-end hosts harboring L3 larvae (
Route of infection. Ingestion of L3 larvae in infected intermediate or paratenic hosts (
Site in human host. Skin, heart, intestinal tract, ears, eyes, CNS (
Gnathostoma malaysiae (Miyazaki & Dunn, 1965)
Geographic distribution. Southeast Asia (
Natural hosts. First intermediate hosts are freshwater copepods. Second intermediate hosts are freshwater fish. Amphibians, birds, rodents, and reptiles can serve as paratenic hosts. Definitive hosts are rodents, including rats. Zoonotic in humans as dead-end hosts harboring L3 larvae (
Route of infection. Ingestion of L3 larvae in infected intermediate or paratenic hosts (
Site in human host. Skin (
Notes. The single case report of G. malaysiae in humans was reported from two Japanese fisherman who described eating raw freshwater shrimp in Myanmar. The species-level identification was considered presumptive (
Gnathostoma nipponicum Yamaguti, 1941
Geographic distribution. Japan, Korea, China (
Natural hosts. First intermediate hosts are freshwater copepods. Second intermediate hosts are freshwater fish. Amphibians, birds, rodents, and reptiles can serve as paratenic hosts. Definitive hosts are weasels and minks. Zoonotic in humans as dead-end hosts harboring L3 larvae (
Route of infection. Ingestion of L3 larvae in infected intermediate or paratenic hosts (
Site in human host. Skin, heart, intestinal tract, ears, eyes, CNS (
Gnathostoma spinigerum Levinsen, 1889
Geographic distribution. Southeast Asia, southern Africa, Madagascar, Australia (
Natural hosts. First intermediate hosts are freshwater copepods. Second intermediate hosts are freshwater fish. Amphibians, birds, rodents, and reptiles can serve as paratenic hosts. Definitive hosts are wild and domestic canids and felids. Zoonotic in humans as dead-end hosts harboring L3 larvae (
Route of infection. Ingestion of L3 larvae in infected intermediate or paratenic hosts (
Site in human host. Skin, heart, intestinal tract, ears, eyes, CNS (
●●●●●●●●●● Camallanida Travassos, 1920
●●●●●●●●●●● Dracunculidae Stiles, 1907
Genus Dracunculus Reichard, 1759
Dracunculus medinensis (Linnaeus, 1758)
Geographic distribution. Focal areas in sub-Saharan Africa, including Chad, Angola, and South Sudan (
Natural hosts. Intermediate hosts are freshwater copepods; freshwater fish and amphibians can serve as paratenic or transport hosts. Definitive hosts are humans; canids, felids, and non-human primates can serve as reservoir hosts (
Route of infection. Ingestion of L3 larvae in infected copepods or paratenic hosts (
Site in human host. Subcutaneous tissues (
Notes.
Reports of D. medinensis infections acquired outside of historically endemic zones and/or in zones where eradication has been well-established are highly likely to represent misidentifications with other nematodes. In limited instances, these represent genuine infections with other unknown Dracunculus spp. (
Dracunculus sp.
Geographic distribution. Vietnam (
Natural hosts. Unknown; presumed zoonotic in humans (
Route of infection. Unknown; presumed ingestion of intermediate or reservoir host.
Site in human host. Subcutaneous abscesses (
Notes. There is a single report of human infection with a non-medinensis Dracunculus species from Vietnam. Genetically it is most similar to D. insignis (Leidy, 1858) and D. lutrae Crichton et Beverley-Burton, 1973, parasites of carnivores (
Spiruroidea, incertae sedis:
Spirurina Type X
Geographic distribution. Japan (
Natural hosts. Intermediate or paratenic hosts are marine squid and fish. Definitive hosts unknown. Zoonotic in humans (
Route of infection. Presumed ingestion of L3 larvae in undercooked squid or fish (
Site in human host. Skin, eyes, ileum (
Notes. Around 50 infections with Spirurina type X larvae have been identified in humans who have consumed various seafood items, particularly small squid species. Molecular studies tentatively identified similar type X larvae as those of Crassicauda giliakiana Skrjaban & Andreeva, 1934, a nematode of Baird’s beaked whale (Berardius bairdii) (
●●●●●●●●●● Thelazioidea Skrjabin, 1915
●●●●●●●●●●● Thelaziidae Skrjabin, 1915
Genus Oxyspirura Dräsche in Stossich, 1897
Geographic distribution. Worldwide (
Natural hosts. Intermediate hosts are arthropods. Definitive hosts are birds and non-human primates. Zoonotic in humans as dead-end hosts harboring L3 larvae (
Route of Infection. Ingestion of infected arthropod intermediate host (
Site in human host. Skin (
Notes. Oxyspirura has been reported as a cause of pruritic cutaneous larval migrans in a patient in Vietnam, but the specimen was not characterized at the species level (
Genus Rictularia Froelich, 1802
Geographic distribution. Worldwide (
Natural hosts. Arthropods are intermediate hosts. A wide range of mammals serve as definitive hosts. Zoonotic in humans (
Route of infection. Presumed ingestion of L3 larvae in infected intermediate hosts.
Site in human host. Appendix (
Notes. The single human case of infection with Rictularia was reported from a patient in New York postmortem (
Genus Thelazia Bosc in Blainville 1819
Thelazia californiensis Price, 1930
Geographic distribution. Western North America (
Natural hosts. Vector intermediate hosts are flies in the genus Fannia. Definitive hosts are mammals, including wild and domestic carnivores, deer, sheep, and lagomorphs. Zoonotic in humans (
Route of infection. Deposition of L3 larvae on the eye by vector fly (
Site in human host. Eye (
Thelazia callipaeda Railliet & Henry, 1910
Geographic distribution. Europe, Asia (
Natural hosts. Vector intermediate hosts are flies in the families Drosophilidae, primarily the genus Phortica. Definitive hosts are mammals, primarily carnivores and lagomorphs. Zoonotic in humans (
Route of infection. Deposition of L3 larvae on the eye by vector fly (
Site in human host. Eye (
Thelazia gulosa (Railliet & Henry, 1910)
Geographic distribution. North America, Europe, Central Asia, Australia (
Natural hosts. Vector intermediate hosts are muscid flies in the genus Musca. Definitive hosts are ungulates, primarily cattle. Zoonotic in humans (
Route of infection. Deposition of L3 larvae on the eye by vector fly (
Site in human host. Eye (
●●●●●●●●● Physalopteroidea Railliet, 1893
●●●●●●●●●● Physalopteridae Railliet, 1893
Genus Physaloptera Rudolfi, 1819
Physaloptera caucasica (von Linstow, 1902)
Geographic distribution. Africa, Asia (
Natural hosts. Intermediate hosts are insects, especially crickets, cockroaches, and beetles. Definitive hosts are non-human primates. Zoonotic in humans (
Route of infection. Presumed ingestion of L3 larvae in infected insects (
Site in human host. Gastrointestinal tract (
Notes. This species is often placed in the genus Abbreviata Travassos, 1926. Eggs consistent with Physaloptera spp. have been recovered from human coprolites in archaeological sites across the world, but species identity has not been established in paleoparasitological cases (
●●●●●●● Rhabditina Chitwood, 1933
●●●●●●●● Rhabditida Orley, 1880
●●●●●●●●● Rhabditidae Orley, 1880
Genus Diploscapter Cobb, 1913
Diploscapter coronata (Cobb, 1893)
Geographic distribution. Worldwide (
Natural hosts. None (environmental); humans are incidental hosts (
Route of infection. Unknown, presumed ingestion of L3 larvae on contaminated produce (
Site in human host. Gastrointestinal tract (
Genus Halicephalobus Timm, 1956
Halicephalobus gingivalis (Stephanski, 1954)
Micronema deletrix Anderson & Bemrick, 1965
Geographic distribution. Worldwide (
Natural hosts. None (environmental); humans are incidental hosts (
Route of infection. Unknown, presumed inoculation of L3 larvae into wounds or mucus membranes; organ transplantation (
Site in human host. Disseminated infection with predilection for CNS (
Genus Pelodera Schneider, 1866
Pelodera strongyloides (Schneider, 1860)
Geographic distribution. Worldwide (
Natural hosts. None (environmental); humans are incidental hosts (
Route of infection. Unknown, presumed direct penetration of skin by L3 larvae or possibly inoculation into wounds (
Site in human host. Skin (
Genus Rhabditis Dujardin, 1845
Geographic distribution. Worldwide (
Natural hosts. None (environmental); humans are incidental hosts (
Route of infection. Unknown, presumed inoculation of L3 larvae into wounds or mucus membranes (
Site in human host. Small intestine, urogenital tract, ear (
Notes. Human cases of Rhabditis are not usually characterized at the species level. There have been cases specifically attributed to R. axei (Cobbold, 1884) from China (
●●●●●●●●● Strongyloididae Chitwood & McIntosh, 1934
Genus Strongyloides Grassi, 1879
Strongyloides fuellborni fuellborni von Linstow, 1905
Geographic distribution. Africa, Southeast Asia (
Natural hosts. Non-human primates. Zoonotic in humans (
Route of infection. Penetration of the skin by L3 larvae (
Site in human host. Small intestine, disseminated infection in immunocompromised hosts, including to the lung, skin, kidneys, and brain (
Strongyloides fuellborni kellyi
Geographic distribution. Papua New Guinea (
Natural hosts. Non-human primates. Zoonotic in humans (
Route of infection. Penetration of the skin by L3 larvae (
Site in human host. Small intestine, disseminated infection in immunocompromised hosts, including to the lung, skin, kidneys, and brain (
Strongyloides myopotami Artigas & Pacheco, 1933
Geographic distribution. South America, North America, Europe, Africa, Asia (
Natural hosts. Nutria. Zoonotic in humans as a dead-end host (
Route of infection. Penetration of skin by L3 larvae (
Site in human host. Skin (
Notes. Strongyloides myopotami causes a short-lived dermatologic reaction in human skin, commonly referred to as ‘nutria itch’ or ‘marsh itch’. The parasite cannot survive in the human host and does not migrate beyond the dermis (
Strongyloides procyonis Little, 1966
Geographic distribution. North America, Asia (
Natural hosts. Raccoons. Zoonotic in humans as a dead-end host (
Route of infection. Penetration of skin by L3 larvae (
Site in human host. Skin (
Notes. Strongyloides procyonis causes a short-lived dermatologic reaction in human skin, commonly referred to as ‘swimmer’s itch’ or ‘marsh itch’. The parasite cannot survive in the human host and does not migrate beyond the dermis (
Strongyloides stercoralis Bavay, 1876
Geographic distribution. Worldwide (
Natural hosts. Humans; dogs may serve as reservoir hosts (
Route of infection. Penetration of the skin by L3 larvae; organ transplantation (
Site in human host. Small intestine, disseminated infection in immunocompromised hosts, including to the lung, skin, kidneys, and brain (
●●●●●●●● Strongylida Molin, 1861
●●●●●●●●● Chabertiidae Popova, 1952
Genus Oesophagostomum Molin, 1861
Oesophagostomum aculaetum (von Linstow, 1879)
Geographic distribution. Southeast Asia, Japan (
Natural hosts. Non-human primates. Zoonotic in humans (
Route of infection. Ingestion of L3 larvae on plants (
Site in human host. Large intestine (
Oesophagostomum bifurcum (Creplin, 1849)
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Non-human primates. Zoonotic in humans (
Route of infection. Ingestion of L3 larvae on plants (
Site in human host. Large intestine (
Oesophagostomum stephanostomum Stossich, 1904
Geographic distribution. Sub-Saharan Africa, Brazil (
Natural hosts. Non-human primates. Zoonotic in humans (
Route of infection. Ingestion of L3 larvae on plants (
Site in human host. Large intestine (
●●●●●●●●● Strongylidae Baird, 1853
Genus Ternidens Railliet & Henry, 1909
Ternidens deminutus (Railliet & Henry, 1905)
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Non-human primates. Zoonotic in humans (
Route of infection. Unknown; presumed ingestion of L3 larvae on contaminated food or fomites, or ingestion of L3 in arthropod intermediate or paratenic hosts (
Site in human host. Large intestine (
●●●●●●●●● Syngamidae Leiper, 1912
Genus Mammomonogamus Ryzhikovk, 1948
Mammomonogamus laryngeus Ryzhikovk, 1948
Geographic distribution. Circumtropical (
Natural hosts. Mammals, including ruminants and felids. Annelids, mollusks, and arthropods may serve as paratenic hosts. Zoonotic in humans (
Route of infection. Unknown, presumed to be from ingestion of embryonated eggs or larvae, or the consumption of a paratenic host (
Site in human host. Bronchial tree (
●●●●●●●●● Ancylostomatidae Looss, 1905
Genus Ancylostoma Dubini, 1843
Ancylostoma braziliense Gomes de Faria, 1910
Geographic distribution. Southern United States, Central and South America, southern Africa, Southeast Asia (
Natural hosts. Wild and domestic canids and felids. Zoonotic in humans as a dead-end host (
Route of infection. Penetration of skin by L3 larvae (
Site in human host. Skin (
Ancylostoma caninum (Ercolani, 1859)
Geographic distribution. Worldwide (
Natural hosts. Wild and domestic canids and felids. Zoonotic in humans (
Route of infection. Penetration of skin by L3 larvae (
Site in human host. Skin, rarely small intestine (
Ancylostoma ceylanicum Looss, 1911
Geographic distribution. Southeast Asia, Australia, Middle East (
Natural hosts. Wild and domestic canids and felids. Zoonotic in humans (
Route of infection. Penetration of skin by L3 larvae (
Site in human host. Small intestine (
Ancylostoma duodenale (Dubini, 1843)
Geographic distribution. Worldwide in tropics and subtropics; host spots of endemicity for human infection are China, India, Egypt, northern Australia, Latin America (
Natural hosts. Mammals, including humans, dogs, cats (
Route of infection. Penetration of skin by L3 larvae (
Site in human host. Small intestine (
Genus Bunostomum Railliet, 1902
Bunostomum phlebotomum (Railliet, 1900)
Geographic distribution. Worldwide (
Natural hosts. Bovids. Zoonotic in humans as a dead-end host (
Route of infection. Penetration of skin by L3 larvae (
Site in human host. Skin (
Genus Necator Stiles, 1903
Necator americanus (Stiles, 1902)
Geographic distribution. Worldwide in tropics and subtropics; hot spots of endemicity for human infection are southern China, southern India, Southeast Asia, sub-Saharan Africa, Latin America, southeastern USA (
Natural hosts. Humans (
Route of infection. Penetration of skin by L3 larvae (
Site in human host. Small intestine (
Necator gorillae Noda & Yamada, 1964
Geographic distribution. Sub-Saharan Africa (
Natural hosts. Gorillas, chimpanzees. Zoonotic in humans (
Route of infection. Penetration of skin by L3 larvae (
Site in human host. Small intestine (
Genus Uncinaria Frölich, 1789
Uncinaria stenocephala (Railliet, 1884)
Geographic distribution. Temperate and subarctic regions of the Northern Hemisphere (
Natural hosts. Carnivores, including wild and domestic canids and felids. Zoonotic in humans as a dead-end host (
Route of infection. Penetration of skin by L3 larvae (
Site in human host. Skin (
●●●●●●●●● Trichostrongylidae Leiper, 1912
Genus Haemonchus Cobb, 1989
Haemonchus contortus (Rudolphi, 1802)
Geographic distribution. Worldwide (
Natural hosts. Many ruminants. Zoonotic in humans (
Route of infection. Ingestion of L3 larvae on contaminated plants and produce (
Site in human host. Small intestine (
Genus Marshallagia Orloff, 1933
Marshallagia marshalli (Ransom, 1907)
Geographic distribution. Worldwide (
Natural hosts. Many ruminants. Zoonotic in humans (
Route of infection. Ingestion of L3 larvae on contaminated plants and produce (
Site in human host. Small intestine (
Genus Nematodirus Ransom, 1907
Nematodirus abnormalis (May, 1920)
Geographic distribution. Worldwide (
Natural hosts. Primarily sheep. Zoonotic in humans (
Route of infection. Ingestion of L3 larvae on contaminated plants and produce (
Site in human host. Small intestine (
Genus Ostertagia Ransom, 1907
Ostertagia ostertagi (Stiles, 1892)
Geographic distribution. Worldwide (
Natural hosts. Primarily bovids; also sheep, goats, equids, and other ruminants. Zoonotic in humans (
Route of infection. Ingestion of L3 larvae on contaminated plants and produce (
Site in human host. Small intestine (
Genus Teladorsagia Andreeva & Satubaldin, 1953
Teladorsagia circumcincta (Stadelman, 1894)
Geographic distribution. Temperate climates (
Natural hosts. Primarily sheep, also goats; zoonotic in humans (
Route of infection. Ingestion of L3 larvae on plants and produce (
Site in human host. Small intestine (
Genus Trichostrongylus Looss, 1905
Trichostrongylus axei (Cobbold, 1879)
Geographic distribution. Worldwide (
Natural hosts. Ungulates, primarily cattle, sheep, goats, and horses. Zoonotic in humans (
Route of infection. Ingestion of L3 larvae on plants and produce (
Site in human host. Small intestine (
Trichostrongylus capricola Ransom, 1907
Geographic distribution. Worldwide (
Natural hosts. Ungulates, primarily cattle, sheep, and goats. Zoonotic in humans (
Route of infection. Ingestion of L3 larvae on plants and produce (
Site in human host. Small intestine (
Trichostrongylus colubriformis (Giles, 1892)
Geographic distribution. Worldwide; predominate in the Middle East (
Natural hosts. Ungulates, primarily cattle, sheep, and goats. Zoonotic in humans (
Route of infection. Ingestion of L3 larvae on plants and produce (
Site in human host. Small intestine (
Trichostrongylus longispicularis Gordon, 1933
Trichostrongylus lerouxi Biocca et al., 1974
Geographic distribution. Worldwide (excluding Africa) (
Natural hosts. Ungulates, primarily cattle, sheep, and goats. Zoonotic in humans (
Route of infection. Ingestion of L3 larvae on plants and produce (
Site in human host. Small intestine (
Trichostrongylus orientalis Jimbo, 1914
Geographic distribution. Southeast Asia, Japan (
Natural hosts. Ungulates, including cattle, sheep, goats, and horses. Zoonotic in humans (
Route of infection. Ingestion of L3 larvae on plants and produce (
Site in human host. Small intestine (
Trichostrongylus vitrinus Looss, 1905
Geographic distribution. Worldwide (
Natural hosts. Ungulates, including sheep, goats. Zoonotic in humans (
Route of infection. Ingestion of L3 larvae on plants and produce (
Site in human host. Small intestine (
●●●●●●●●● Angiostrongylidae Boehm & Gebauer, 1934
Genus Angiostrongylus Kamensky, 1905
Angiostrongylus cantonensis (Chen, 1935)
Geographic distribution. Asia, South Pacific, Hawaii, Caribbean, Africa, southern United States, Central and South America (
Natural hosts. Intermediate hosts are terrestrial mollusks. Paratenic hosts include reptiles, amphibians, planarians. Definitive hosts are rodents, primarily rats (Rattus) and cotton rats (Sigmodon). Zoonotic in humans as a dead-end host harboring L4 larvae and young adults (
Route of infection. Ingestion of L3 larvae in infected mollusks or paratenic hosts (
Site in human host. CNS (
Angiostrongylus costaricensis Morera & Cespedes, 1971
Geographic distribution. Southern United States, Central and South America (Romero-Alegria 2014).
Natural hosts. Intermediate hosts are terrestrial mollusks. Definitive hosts are rodents. Zoonotic in humans (Romero-Alegria 2014).
Route of infection. Ingestion of L3 larvae in infected mollusks or contaminated produce (Romero-Alegria 2014).
Site in human host. Mesenteric blood vessels (Romero-Alegria 2014).
Angiostrongylus malaysiensis Bhaibulaya & Cross, 1971
Angiostrongylus cantonensis Malaysia strain
Geographic distribution. Southeast Asia (
Natural hosts. Intermediate hosts are terrestrial mollusks. Paratenic hosts include reptiles, amphibians, planarians. Definitive hosts are rodents, primarily rats. Apparently zoonotic in humans as a dead-end host harboring larvae (
Route of infection. Ingestion of L3 larvae in infected mollusks or paratenic hosts (
Site in human host. CNS (
●●●●●●●●● Metastrongylidae Leiper, 1909
Genus Metastrongylus Molin, 1861
Metastrongylus elongatus Dujardin, 1845
Strongylus apri Gmelin, 1790
Geographic distribution. Worldwide (
Natural hosts. Intermediate hosts are earthworms. Definitive hosts are wild and domestic pigs. Zoonotic in humans (
Route of infection. Presumed ingestion of L3 larvae in infected earthwormsv
Site in human host. Lungs (
Metastrongylus salmi Gedoelst, 1923
Geographic distribution. Worldwide (
Natural hosts. Wild and domestic swine are definitive hosts; one incidental infections in reported in a human (
Route of infection. Presumed ingestion of L3 larvae in infected earthworms.
Site in human host. Lungs (
The following genera and species have been previously reported as human parasites. They are excluded from the above checklist because it is not believed they can cause parasitic infection in the human host, are based on demonstrable misidentifications, confirmation of identification is required, or because of taxonomic changes. The organisms are listed in alphabetical order.
Agamomermis
spp. Members of the genus Agamomermis are mermithid nematodes that are free-living as adults but infect insects as larvae. Human cases are believed to represent spurious passage following accidental ingestion of worms in contaminated food or water (
Amblyomma argentinae
Neumann, 1905. This Neotropical tick was recorded as a human parasite under its synonym A. testudinis (Conil, 1877) (Doss 1974), but that record is believed to be in error (
Amblyomma auricularium
(Conil, 1878). This Neotropical tick is a parasite of several groups of mammals and birds. Records of this species from humans are believed to represent misidentifications, primarily of A. parvum (
Amblyomma calcaris
Nakatsudi, 1942. This tick was described from a human in China (
Amblyomma compressum
(Macalister, 1872). This African tick species is a parasite of mammals, especially pangolins and rodents, birds, and reptiles. Records of this species from unknown locations in Africa (
Amblyomma geayi
Neumann, 1899. This tick is a parasite of various mammals and birds in Central and South America. A record of this species from a human (
Amblyomma helvolum
Koch, 1844. This Southeast Asian tick is primarily a parasite of reptiles, and occasionally mammals. Records of this species feeding on humans (Doss 1974) is based on an earlier publication that stated the ticks were merely crawling on humans (Audy 1960). To date, there are no records of A. helvolum feeding on humans (
Amblyomma macfarlandi
Kierans et al., 1973. This tick is a parasite of tortoises on the Galapagos Islands. The single record from a human (
Amblyomma pomposum
Dönitz, 1909. This African tick is a parasite of several groups of mammals and birds. Records from humans require confirmation (
Amblyomma sylvaticum
(De Geer, 1778). This tick is a parasite of reptiles in South Africa. Records of this species from humans are believed to represent misidentifications (
Amblyomma usingeri
Keirans et al., 1973. This tick is a parasite of tortoises on the Galapagos Islands. The single record from a human (
Amphimermis elegans
(Hagmeier, 1912). Amphimermis elegans is an Asian mermithid nematode parasitic on orthopteran insects. A human case (as Mermis) reportedly recovered from urine probably represents pseudoparasitism or contamination of the toilet by the insect host (
Androlaelaps casalis
(Berlese, 1887). This laelapid mite is a predator on other mites and insects. It was reported as a cause of human dermatitis in Israel (
Anisopus sp. Anisopodid flies are commonly called wood gnats or window gnats. They have been implicated in intestinal and urogenital myiasis (
Bertiella satyri
Blanchard, 1891. This cestode was originally described from orangutans. Reports from humans (
Caccobius vulcanus
(Fabricius, 1801). Caccobius vulcanus is a Palearctic coprophagous scarab beetles that has been implicated as a cause of scarabiasis in India (as C. mutans Sharp, 1875) (
Clogmia albipunctata
(Williston, 1893). Clogmia albipunctata is a psychodid fly with a nearly worldwide distribution. This species has been implicated as a cause of urogenital (
Crasodactylus punctatus
Guérin-Méneville, 1847. This carabid beetle was reported from the ear of two patients in Oman (misspelled as Crasydactylus punctatus) (
Cryptostrongylus pulmoni
. The name Cryptostrongylus pulomoni is a provisional name given to suspect helminths associated with chronic fatigue syndrome (
Cyclocephala borealis
Arrow, 1911. This scarab beetle was implicated in a large-scale infestation of the ears of Boy Scouts in Pennsylvania, USA (
Dermacentor cruentus
Koch, 1844. This European tick was listed as a human parasite based on the original description (Doss 1974), but there is no indication in the original description it was observed feeding on humans (
Dermacentor halli
McIntosh, 1931. This tick is a parasite of various mammals in North and Central America. Records from humans require confirmation (
Dermacentor taiwanensis
Sugmito, 1935. This tick is a parasite of various mammals in China, Vietnam, and Taiwan. Records of this species from humans are believed to represent misidentifications (
Dibothriocephalus alascense
(Rausch & Rausch, 1956). This species was originally described from a domestic dog in the Yukon-Kuskokwim Delta of Canada. A single human case of this species was reported from an Eskimo in Alaska (
Diphyllobothrium cameroni
Rausch, 1969. This species was originally described from the Hawaiian monk seal (Neomonachus schauinslandi) and has been recorded twice from humans in Japan (Kamo H. 1986), but the records are considered doubtful (
Diphyllobothrium elegans
(Krabbe, 1865). This is a parasite of seals and has been described once from a human in Japan (Kamo H. 1986), but the record is considered doubtful (
Diphyllobothrium orcini
Hatsushika & Shirouzu, 1990. This species was described from killer whales. There are two records from humans from Japan (Kifune 2000; Nakazawa 1992), but those records are considered doubtful (
Diphyllobothrium scoticum
(Rennie & Reid, 1912). This species was described from the leopard seal (Hydrurga leptonyx) and has been recorded once from a human in Japan (Fukumoto 1988), but that record is considered doubtful (
Drosophila melanogaster
Meigen, 1830. This common ‘fruit fly’ has been infrequently reported as a cause of nasal and ocular myiasis (
Dryomyza formosa
(Wiedemann, 1830). This dryomyzid fly was reported as a cause of gastrointestinal myiasis in a patient from Japan suffering from delusional parasitosis. Larvae were observed in fresh stool and it was speculated they represent spurious passage following accidental ingestion of the larvae (
Emys orbicularis (Linnaeus, 1758). Emys orbicularis is the Latin name of the European pond turtle. This name was used in the 23rd edition of “Manson’s Tropical Diseases” (Farrar 2014) as a species of leech that parasitizes humans. This probably represents an editorial error and may have been intended to refer to a leech that normally parasitizes the turtle.
Eristalis tenax
(Linnaeus, 1758). This syrphid fly is frequently implicated in causing intestinal or urogenital myiasis (
Euparyphium spp. Members of this genus of echinostome flukes has been recorded from humans in Laos (
Fannia scalaris
(Fabricius, 1794). This fly was reported as a cause of urogenital myiasis in 1975 (
Gordius
spp. A number of “gordiid worms” or “horsehair worms”, including Gordius, have been recovered from humans (typically in vomitus) (
Haemaphysalis cinnabarina
Koch, 1844. Records of this Brazilian tick from humans refer to H. chordeilis (
Haemaphysalis kashmirensis
Hoogstraal & Varma, 1962. This tick is a parasite of mammals and reptiles in India and Pakistan. Records from humans require confirmation (
Haemaphysalis muhsamae
Santos Dias, 1954. This tick is a parasite of birds in Africa. Records of this species from humans require confirmation due to the morphologic challenges in identifying this species (
Haemaphysalis proxima
Aragão, 1911. This species has been recorded from humans in Colombia. There is no formal description for this species and the name is considered nomen nudum (
Haemaphysalis warburtoni
Nuttall, 1912. This tick is a parasite of bovids and rodents in India, Nepal, and China. Records from humans may be based on misidentifications and require confirmation (
Hyalomma franchinii
Tonelli-Rondelli, 1932. This tick is a parasite of mammals and reptiles in North Africa and the Middle East. Records from humans are based on misidentifications of H. excavatum and H. marginatum (
Hyalomma impressum
Koch, 1844. This tick is a parasite of various mammals and birds from sub-Saharan Africa. This species has been recorded from a human in South Africa (
Hyalomma plubeum
(Panzer, 1795). This name is currently considered incertae sedis, and records of H. plumbeum from humans currently pertain to H. marginatum (
Hermetia spp. Larvae of these soldier flies have been implicated in cases of intestinal and furuncular myiasis (
Ixodes affinis
Neumann, 1899. This North and Central American tick is primarily a parasite of a wide variety of mammals, including carnivores, marsupials, and ungulates. The species is difficult to identify morphologically and past records of this species from humans are believed to be misidentifications (
Ixodes humanus
Koch, 1844. This species was described from a human in Brazil, however the identity of the species is not fully understood and it may be synonymous with a member of the genus Amblyomma (
Ixodes jellisoni
Cooley & Kohls, 1938. This is a North American tick found on rodents and carnivores. Records of this species from humans are believed to be misidentifications (
Ixodes laysanensis
Wilson, 1964. This tick is a bird parasite in Hawaii. Records of this species feed in humans (Doss 1974) are based on an earlier record that reported the tick crawling, and not feeding, on humans. To date, there is no evidence I. laysanensis feeds on humans (
Ixodes loricatus
Neumann, 1899. This tick is a parasite of marsupials and rodents in South America. Records from humans in Brazil (Serra-Freire 2011) require confirmation and are provisionally excluded as a parasite of humans (
Ixodes luciae
Sénevet, 1940. This species is a Neotropical tick of various mammals, especially marsupials and rodents. The single record of this species on a human from Argentina (Ivancovich 1992) is believed to be based on a misidentification (
Ixodes molestus
James, 1923. This species was described as attacking humans in the USA, but the name is currently regarded as nomen dubium (
Ixodes simplex
Neumann, 1906. Records of this broadly-distributed Old World tick species of bats on humans from Japan cannot be confirmed and may be based on misidentifications (
Ixodes trichosuri
Roberts, 1960. This tick species is a parasite of marsupials and rodents in Australia. Records of this parasite infecting humans (
Lasioderma serricorne
(Fabricius, 1792). Lasioderma serricorne is a cosmopolitan pest of dried, organic materials, including tobacco, cereals and other grains, dried fruit, and dried animal products. It was been reported as cause of canthariasis in infants in China (
Ligula spp. Ligula species are diphyllobothriid parasites of fish-eating birds. There are two reports from humans, initially reported under the names Diplogonophorus brauni Leon, 1907 and Braunia jassyensis Leon, 1908. These records are believed to represent misidentifications (
Lophomonas blattarum
Stein, 1860. There are many case reports in the literature of L. blattarum being isolated from human respiratory specimens. These all appear to be misidentifications of ciliocytophthoria, a condition whereby detached, motile epithelial cells are observed in clinical specimens (
Maladera castanea
(Arrow, 1913). This scarab beetle was implicated in a large-scale infestation of the ears of Boy Scouts in Pennsylvania, USA (as Autoserica castanea) (
Melophagus ovinus
(Linnaeus, 1758). Commonly called the ‘sheep ked’, M. ovinus is a cosmopolitan parasite of domestic sheep (Ovus aries), as well as wild ungulates, rabbits, and wild and domestic canids. It has been reported as parasitizing humans (
Musca nebulo
Fabricius, 1794. This species was reported as cause of oral myiasis in India (
Muscina spp. Flies in the genus Muscina have repeatedly been reported as causing intestinal myiasis following the recovery of fly larvae in stool (
Onthophagus bifasciatus
(Fabricius, 1781). Onthophagus bifasciatus is a Palearctic dung beetle that has been implicated as a causative agent of scarabiasis in India (
Onthophagus unifasciatus
(Schaller, 1783). Onthophagus unifasciatus is a Palearctic dung beetle that has been implicated as a causative agent of scarabiasis in Sri Lanka (
Palpoda scutellaris
(Fabricius, 1805). This is a species of syrphid fly from Central and northern South America. It was reported as the cause of human intestinal myiasis in Costa Rica (
Parachordodes spp. A number of “gordiid worms” or “horsehair worms”, including Parachordodes, have been recovered from humans (typically in vomitus) (
Paragordius varius
(Leidy, 1851). A number of “gordiid worms” or “horsehair worms”, including Paragordius, have been recovered from humans (typically in vomitus) (
Pericoma spp. Pericoma is a genus of Psychodidae that has been implicated as a cause of urinary myiasis in India (
Piophila casei
(Linnaeus, 1758). This species, commonly called the ‘cheese fly’, has been infrequently reported as a cause of intestinal or urogenital myiasis (
Psychoda albipennis
Zetterstedt, 1850. This psychodid has been implicated as an agent of urogenital myiasis (
Psychoda alternata
Say, 1824. This psychodid has been implicated as an agent of urogenital myiasis (
Psychoda sexpunctata
Curtis, 1839. This psychodid has been implicated as a source of gasterointestinal myiasis (
Rhipicentor bicornis
Nutall & Warburton, 1908. This tick is a parasite of various mammals in sub-Saharan Africa. This species was recorded as a parasite on humans (Doss 1974), however that record is based on a misunderstanding that a tick observed in a human dwelling meant it feeds on humans. To date, there are no records of R. bicornis feeding on humans (
Sappinia diploidea
(Hartmann & Naegler, 1908). The first case of human infection with a member of the genus Sappinia was reported to have been caused by S. diploidea based on morphologic criteria (
Scarites sulcatus
Olivier, 1795. Scarites sulcatus is a Palearctic ground beetle that has been implicated as a cause of genital canthariasis (
Scenopinus spp. Members of this genus of flies have been implicated in urogenital myiasis (Thompson et al. 1970). Larvae of Scenopinus are predators on the larvae of other insects. The presence of Scenopinus larvae in clinical specimens is probably incidental.
Trichophrya piscium
Bütschli, 1899. This freshwater fish pathogen was reported was reported from sinus aspirates of a patient in Iraq (
Tyroglyphus longior
(Gervais, 1844). This grain mite has been implicated in intestinal acariasis by the finding of mites in the stool of two patients with generalized intestinal complaints (
Tyroglyphus putrescentiae
(Schrank, 1781). This grain and mold mite has been implicated as a cause of intestinal acariasis (
Urbanorum
. The name ‘Urbanorum’ has been given to usual objects observed in stool specimens. Most cases have been reported from Central and South America (
The authors would like to thank Dr. Sina Adl for reviewing the manuscript prior to submission.
Disclaimer: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.