A ten-year inventory of the Gaoligongshan in western Yunnan Province, China, yielded more than 1000 adult spider specimens belonging to the symphytognathoid families Theridiosomatidae, Mysmenidae, Anapidae, and Symphytognathidae. These specimens belong to 36 species, all newly described here. In the Theridiosomatidae: Epeirotypus dalong n. sp., Ogulnius barbandrewsi n. sp., Baalzebub nemesis n. sp., Theridiosoma diwang n. sp., Theridiosoma shuangbi n. sp., Zoma dibaiyin n. sp., Wendilgarda muji n. sp., Coddingtonia euryopoides n. gen., n. sp.; in the Mysmenidae: Mysmena changouzi n. sp., Mysmena jinlong n. sp., Mysmena bizi n. sp., Mysmena goudao n. sp., Mysmena haban n. sp., Mysmena shibali n. sp., Simaoa yaojia n. gen., n. sp., Simaoa kavanaugh n. sp., Simaoa maku n. sp., Simaoa bianjing n. sp., Gaoligonga changya n. gen., n. sp., Gaoligonga zhusun n. sp., Mosu nujiang n. gen., n. sp., Mosu huogou n. sp., Chanea suukyii n. gen., n. sp., Maymena paquini n. sp., Maymena kehen n. sp.; in the Anapidae: Gaiziapis zhizhuba n. gen., n. sp.; in the Symphytognathidae: Patu jidanweishi n. sp., Patu qiqi n. sp., Patu xiaoxiao n. sp., Crassignatha pianma n. sp., Crassignatha yinzhi n. sp., Crassignatha quanqu n. sp., Crassignatha yamu n. sp., Crassignatha ertou n. sp., Crassignatha gudu n. sp., Crassignatha longtou n. sp. The first species of Zoma Saaristo, 1996 (previously monotypic, known from the Seychelles) and Maymena Gertsch, 1960 (previously known from the Americas) are reported from China. The genus Crassignatha Wunderlich, 1995 (previously known from a single male from Malaysia) is represented by seven new Chinese species and is transferred to Symphytognathidae. The first Epeirotypus O. Pickard-Cambridge, 1894 species from beyond the Neotropics is described, although the presence of the genus in Asia was previously noted. Notes on morphological characters exhibited by this fauna and implications for the limits and diagnosis of some symphytognathoid families are given. Dichotomous keys to species are provided. Quantitative biodiversity analysis suggests a high degree of endemism for symphytognathoids in the Gaoligongshan.